A5047292310- Schizophrenia research and treatment
- Mental Health and Psychiatry
- Mental Health Treatment and Access
- Psychosomatic Disorders and Their Treatments
- Neurobiology of Language and Bilingualism
- Functional Brain Connectivity Studies
- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Mental Health and Patient Involvement
- Epilepsy research and treatment
- Mental Health via Writing
- Neuroscience and Music Perception
- Stuttering Research and Treatment
- Mental Health Research Topics
- Obsessive-Compulsive Spectrum Disorders
- Child and Adolescent Psychosocial and Emotional Development
- Eating Disorders and Behaviors
- Language, Metaphor, and Cognition
- Language Development and Disorders
- Sleep and related disorders
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Sleep and Wakefulness Research
- Spanish Linguistics and Language Studies
- COVID-19 and Mental Health
- Family Support in Illness
Icahn School of Medicine at Mount Sinai
2019-2024
Long Island University
2022-2024
New York University
2018-2022
University School
2022
NYU Langone Health
2019
Epilepsy Foundation
2019
Abstract Slow oscillations and spindle activity during non-rapid eye movement sleep have been implicated in memory consolidation. Closed-loop acoustic stimulation has previously shown to enhance slow improve verbal associative memory. We assessed the effect of closed-loop a daytime nap on virtual reality spatial navigation task 12 healthy human subjects randomized within-subject crossover design. show robust enhancement oscillation sleep. However, no effects behavioral performance were...
Abstract Aberrant pauses are characteristic of schizophrenia and robustly associated with its negative symptoms. Here, we found that pause behavior was symptoms in individuals at clinical high risk (CHR) for psychosis, measures syntactic complexity—phrase length usage determiners introduce clauses—that previously showed this same CHR cohort to help comprise a classifier predicted psychosis. These findings suggest common impairment discourse planning verbal self-monitoring affects both speech...
Individuals at clinical high risk for psychosis (CHR) report a strong desire psychoeducation, and guidelines recommend psychoeducation in early care. Although several CHR models have been developed, additional research is needed to establish the effectiveness of these models. The goal this study was conduct pilot trial Brief Educational Guide Need (BEGIN). BEGIN brief structured intervention designed educate individuals on symptoms treatment options. We conducted feasibility 25 (60% female,
Abstract Direct recordings from the human brain have historically involved epilepsy patients undergoing invasive electroencephalography (iEEG) for surgery. However, these measurements are temporally limited and affected by clinical variables. The RNS System (NeuroPace, Inc.) is a chronic, closed-loop electrographic seizure detection stimulation system. When adapted investigators research, it facilitates cognitive testing in controlled ambulatory setting, with collected over months to years....
Abnormalities in the semantic and syntactic organization of speech have been reported individuals at clinical high-risk (CHR) for psychosis. The current study seeks to examine whether such abnormalities are associated with changes brain structure functional connectivity CHR individuals.Automated natural language processing analysis was applied samples obtained from 46 22 healthy individuals. Brain structural resting-state imaging data were also acquired all participants. Sparse canonical...
Abstract Aim There is concern that the provision of clinical high risk for psychosis (CHR) label stigmatizing. Prior research suggests people have nuanced reactions to feedback involving CHR label, including a positive experience receiving and improvement in negative emotions (e.g., shame), while also exhibiting concerns about self‐perception perceptions from others related label. The current pilot study aimed evaluate whether individuals at showed changes emotional stigma‐related...
Qualitative research can shed light on the subjective experiences of individuals at clinical high risk (CHR) for psychosis, complement quantitative research, broaden our understanding experiencing CHR, and inform intervention development. The aim this study was to explore life CHR through qualitative research.Participants were 37 (20 male, 17 female) aged 16-34 (Mage = 23.32 ± 5.26), 16 healthy controls (HCs; 7 9 18-34 25.37 4.05). data obtained open-ended interviews (30-45 min). No a priori...
Abstract Aim Identification of individuals with psychosis risk (PR) through screening and specialized assessment is becoming more widespread in an effort to promote early intervention improve recovery outcomes. PR report interest psychoeducation, though such interventions are currently lacking. Our goal was develop a structured psychoeducation grounded theory stakeholder feedback. Methods By following step‐by‐step development model, we identified relevant conceptual frameworks, developed the...
Abstract Many individuals with psychotic symptoms have less complex language than healthy individuals. Word etymology is a lexical feature that has not yet been studied in clinical populations, but among individuals, words of Old French origin are chosen over Germanic-origin to convey formality (e.g. “inquire” vs. “ask”). Differences complexity may relate differences etymological content speech. Here, we determined the proportion word use and Old-French-origin large cohort recent-onset...
Prior qualitative studies show that individuals with psychoticlike experiences express difficulties concerning their identity. However, previous work has studied at clinical high risk for psychosis (CHR) and first-episode (FEP) separately. Here, we compare the of CHR, FEP, healthy individuals.
Schizophrenia is characterized by disturbances in thought and language, often resulting reduced production complexity of speech, abnormal pauses; these language have been associated with negative symptoms (Cohen et al., 2016). Using clinical ratings, we others shown that both are evident prior to psychosis onset youths at high risk (CHR). Automated natural processing (NLP) analyses transcribed speech show reductions semantic coherence syntactic predict CHR individuals (Bedi 2015). In the...
Background The COVID-19 pandemic is expected to increase stress and mental health symptoms. We present the case of a young man at risk for psychosis who has paradoxically shown symptomatic functional improvement as result circumstances produced by COVID-19. These changes were unexpected given client's persistent struggles in year leading up outbreak United States expectation an exacerbation psychotic-like
Face processing deficits characterize schizophrenia, including in prodromal stages. Baseline face predict psychosis onset clinical high-risk (CHR) youths, specifically fear/anger (Corcoran, 2015). Here, we evaluate the predictive value for onset, of speed CHR youths. In a cohort 49 patients (of whom 7 later transitioned to psychosis), and 31 healthy controls, examined reaction times using UPenn battery, Emotion Recognition (ER-40; Kohler 2005), Discrimination (EMODIFF), Emotional Acuity...
Abstract Background Clinicians have long observed peculiarities in the use of figurative language by individuals with schizophrenia, as part larger expressive deficits. Natural processing has been used to predict psychosis onset (Bedi et al., 2015; Corcoran 2018), identifying classifiers such semantic coherence. Here we examine metaphor across spectrum. Methods Participant groups spectrum (healthy controls, clinical high risk for and schizophrenia) participated open-ended interviews lasting...