A5100785772- Animal Virus Infections Studies
- Virus-based gene therapy research
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Insect-Plant Interactions and Control
- Tuberculosis Research and Epidemiology
- Microbial infections and disease research
- Hymenoptera taxonomy and phylogeny
- Plant and animal studies
- Aquaculture disease management and microbiota
- Virology and Viral Diseases
- Herpesvirus Infections and Treatments
- Crop Yield and Soil Fertility
- Viral Infectious Diseases and Gene Expression in Insects
- MicroRNA in disease regulation
- Pneumocystis jirovecii pneumonia detection and treatment
- Plant Parasitism and Resistance
- Metabolomics and Mass Spectrometry Studies
- Ginseng Biological Effects and Applications
- Silicon and Solar Cell Technologies
- Insect Pest Control Strategies
- Plant Virus Research Studies
- Complement system in diseases
- Plant Stress Responses and Tolerance
- Erythrocyte Function and Pathophysiology
University of Virginia
2025
Traditional Chinese Medicine Hospital of Kunshan
2024
Shanghai University of Traditional Chinese Medicine
2024
Chinese Academy of Agricultural Sciences
2013-2023
Harbin Veterinary Research Institute
2013-2023
Fujian Agriculture and Forestry University
2001-2021
Ministry of Education of the People's Republic of China
2021
Zhejiang University
2014-2020
Pudong New Area People's Hospital
2019
Shangluo University
2010-2018
Drought stress has become an increasingly serious environmental issue that influences the growth and production of watermelon. Previous studies found arbuscular mycorrhizal (AM) colonization improved fruit yield water use efficiency (WUE) watermelon grown under stress; however, exact mechanisms remain unknown. In this study, effects Glomus versiforme symbiosis on growth, physio-biochemical attributes, stress-responsive gene expressions seedlings well-watered drought conditions were...
Background Porcine circovirus type 2 (PCV2) is considered to be the primary causative agent of postweaning multisystemic wasting syndrome (PMWS), which has become a serious economic problem for swine industry worldwide. The major genotypes, PCV2a and PCV2b, are highly prevalent in pig population present However, another newly emerging PCV2b genotype mutant, mutation its ORF2-encoded capsid protein, been sporadically China, as well other countries. It therefore important determine relative...
Abstract Cardiovascular diseases (CVDs) continue to drive global mortality rates, underscoring an urgent need for advancements in healthcare solutions. The development of point‐of‐care (POC) devices that provide rapid diagnostic services near patients has garnered substantial attention, especially as traditional systems face challenges such delayed diagnoses, inadequate care, and rising medical costs. advancement machine learning techniques sparked considerable interest research engineering,...
This study aimed to discover the novel noninvasive biomarkers for diagnosis of pulmonary tuberculosis (TB). We applied iTRAQ 2D LC-MS/MS technique investigate protein profiles in patients with TB and other lung diseases. A total 34 differentially expressed proteins (24 upregulated ten downregulated proteins) were identified serum patients. Significant differences S100-A9 (S100A9), extracellular superoxide dismutase [Cu-Zn] (SOD3), matrix metalloproteinase 9 (MMP9) found between diseases by...
The epidemic of pulmonary tuberculosis (TB), especially multidrug-resistance (MDR-TB) presented a major challenge for TB treatment today.We performed iTRAQ labeling coupled with two-dimensional liquid chromatography-tandem mass spectrometry (2D LC-MS/MS) and Solexa sequencing among MDR-TB patients, drug-sensitive (DS-TB) healthy controls.A total 50 differentially expressed proteins 43 miRNAs (fold change >1.50 or <0.60, P<0.05) were identified in the patients compared to both DS-TB...
Rapid diagnosis of pulmonary tuberculosis is an effective measure to prevent the spread tuberculosis. However, grim fact that new, rapid, and safe methods for clinical are lacking. Moreover, although auto-lysosome critical in clearing Mycobacterium tuberculosis, pathological significance microRNAs, as biomarkers autophagosome maturation unclear. Here, these microRNAs were investigated by Solexa sequencing qPCR validation, a potential diagnostic model was established logistic regression....
Rapid and efficient methods for the determination of cured tuberculosis (TB) are lacking. A total 85 differentially expressed serum proteins were identified by iTRAQ labeling coupled with two-dimensional liquid chromatography-tandem mass spectrometry (2D LC-MS/MS) analysis (fold change >1.50 or <0.60, P < 0.05). We validated albumin (ALB), Rho GDP-dissociation inhibitor 2 (ARHGDIB), complement 3 (C3), ficolin-2 (FCN2), apolipoprotein (a) (LPA) using enzyme-linked immunosorbent assay (ELISA)...
Continuous cropping of watermelon (Citrullus lanatus L.) can lead to reduced yield and quality. We aimed determine the effects cattle manure addition rotation with green garlic improve reduce disease incidence in examine on biological chemical characteristics soil. Field experiments were performed during 2012–2014 land previously under two years continuous northwest China. examined three treatment combinations: rotation, application before planting, combined crop rotation. Watermelon...
ABSTRACT Apoptosis is an essential strategy of host defense responses and used by viruses to maintain their life cycles. However, the apoptotic signals involved in virus replication are poorly known. In present study, we report molecular mechanism induction viral protein ORF4, a newly identified porcine circovirus type 2 (PCV2). detection revealed not only that activity caspase-3 -9 increased PCV2-infected ORF4-transfected cells but also cytochrome c release from mitochondria cytosol...
The genome of porcine circovirus type 2 (PCV2) contains two major open reading frames, which have been shown to encode the virus capsid and replication-associated proteins. protein is a structural virus; it can be suitable target antigen for detecting PCV2-specific antibodies monitor PCV2 infection. To produce antigen, coding sequence was cloned into baculovirus transfer vector, recombinant (rC) expressed as combined fusion in frame with C-terminal peptide six histidines. affinity-purified...
Abstract Background Porcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent of porcine (PRRS) circovirus type 2 (PCV2) associated with postweaning multisystemic wasting (PMWS) in pigs. Coinfection highly pathogenic PRRSV (HP-PRRSV) PCV2 field has recently become extensive some Asian countries. A synergistic pathogenicity between infections previously been reported. However, consequences sequential infection pigs these two viruses are unknown. Methods Thirty...
Soil water movement is a critical consideration for crop yield in straw-integrated fields. This study used an indoor soil column experiment to determine infiltration and evaporation characteristics three forms of direct soils (straw mulching, straw mixing inter-layering). Straw mulching covering the land surface with straw. top 10 cm soil. Then inter-layering placing at 20 depth. There are generally good correlations among mulch integration methods p &lt; 0.05, average errors/biases...
The aim of this study was to discover novel biomarkers for pulmonary tuberculosis (TB). Differentially expressed proteins in the serum patients with TB were screened and identified by iTRAQ-two dimensional liquid chromatography tandem mass spectrometry analysis. A total 79 abnormal discovered compared healthy controls. Of these, significant differences observed 47 abnormally between or pneumonia chronic obstructive disease (COPD). Patients (n = 136) exhibited significantly higher levels...
Porcine circovirus type 2 (PCV2) is an important pathogen in swine herds, and its infection of pigs has caused severe economic losses to the pig industry worldwide. The capsid protein PCV2 only structural that associated with immunity. Here, we report a neutralizing monoclonal antibody (MAb), MAb 3A5, binds intact virions PCV2a, PCV2b, PCV2d genotypes. 3A5 neutralized by blocking viral attachment PK15 cells. To further explore neutralization mechanism, resolved structure virion complex Fab...
Single nucleotide polymorphisms (SNPs) within precursor microRNAs (miRNAs) can affect miRNAs expression, and may be involved in the pathogenesis of pulmonary tuberculosis (TB). This study aimed to investigate potential associations between four miRNA SNPs (miR-146a C > G, miR-149 T C, miR-196a2 miR-499 C) susceptibility TB Chinese Uygur, Kazak, Southern Han populations. A case-control was performed on Uygur (n = 662), Kazak 612), 654) populations using PCR-PFLR method. The allele genotype...
Psyttalia incisi (Silvestri) is the dominant parasitoid against Bactrocera dorsalis (Hendel) in fruit-producing regions of southern China. Prior to a large-scale release, it important generate sufficient stockpile P. whilst considering how best maintain their quality and performance; cold storage an ideal method achieve these aims. In this study, impacts temperature duration on developmental parameters pupae at different age intervals were assessed. Then, four protocols chosen for further...