Yanyan Zhang

ORCID: 0000-0003-3993-7792
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About
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Research Areas
  • Thyroid Cancer Diagnosis and Treatment
  • Cancer-related Molecular Pathways
  • Melanoma and MAPK Pathways
  • Growth Hormone and Insulin-like Growth Factors
  • Endometriosis Research and Treatment
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Cancer, Hypoxia, and Metabolism
  • Ovarian cancer diagnosis and treatment
  • Esophageal Cancer Research and Treatment
  • Cancer-related molecular mechanisms research
  • Air Quality Monitoring and Forecasting
  • Reproductive Biology and Fertility
  • Cardiovascular and exercise physiology
  • Radiomics and Machine Learning in Medical Imaging
  • Pancreatic and Hepatic Oncology Research
  • MRI in cancer diagnosis
  • Ovarian function and disorders
  • Mesenchymal stem cell research
  • Metabolism, Diabetes, and Cancer
  • Cancer Diagnosis and Treatment
  • Diet, Metabolism, and Disease
  • Thyroid Disorders and Treatments
  • Effects and risks of endocrine disrupting chemicals
  • Advanced Chemical Sensor Technologies
  • Lung Cancer Diagnosis and Treatment

Yangzhou University
2025

Beijing YouAn Hospital
2023

Capital Medical University
2023

Jiangjin Central Hospital
2022

Chongqing University
2022

First Hospital of Jilin University
2020

Jilin University
2020

First Hospital of Shanxi Medical University
2018

Shanxi Medical University
2018

First Affiliated Hospital of Zhengzhou University
2018

ABSTRACT Background Advances in imaging technology have enhanced the detection of pulmonary nodules. However, determining malignancy often requires invasive procedures or repeated radiation exposure, underscoring need for safer, noninvasive diagnostic alternatives. Analyzing exhaled volatile organic compounds (VOCs) shows promise, yet its effectiveness assessing nodules remains underexplored. Methods Employing a prospective study design from June 2023 to January 2024 at Affiliated Hospital...

10.1002/cam4.70545 article EN cc-by Cancer Medicine 2025-01-01

The polymorphisms of the tumor suppressor gene p53 have been extensively investigated in numerous malignant tumors, particularly carcinomas associated with human papillomavirus (HPV) infection. However, results remain controversial. To address a potential correlation between genotypes and risk esophageal squamous cell carcinoma (ESCC), we codon 72 polymorphism 435 patients ESCC 550 cancer-free subjects from same geographical region. Arg/Arg genotype was significantly increased cases compared...

10.1002/mc.20368 article EN Molecular Carcinogenesis 2007-10-04

Background Obesity is a risk factor for endometrial cancer (EC). However, it not known how insulin receptor isoform A (IR-A) and insulin-like growth 1 (IGF-1R), cognate receptors IGFs, respectively, regulate malignant behaviors of EC. In this study, we examined the biological effects IR-A/IGF-1R, explored downstream signaling cascades, assessed therapeutic potential targeting IR-A/IGF-1R in vivo.Methods The expression levels IR-A IGF-1R were by qRT-PCR Western blotting. Upon down-regulating...

10.1080/15384047.2018.1529096 article EN Cancer Biology & Therapy 2018-11-14

In previous studies, the B-Raf proto-oncogene, serine/threonine kinase (BRAF)V600E mutation has been identified in multiple malignant tumors. BRAFV600E revealed to contribute tumorigenesis by activation of phospho-mitogen-activated protein kinases (MAPKs) and their downstream Monopolar spindle 1 (Mps1), leading chromosome euploidy tumor development. present study, presence phospho-MAPK Mps1 161 thyroid carcinoma cases with complete clinical parameters was analyzed immunohistochemistry, BRAF...

10.3892/ol.2018.8561 article EN Oncology Letters 2018-04-24

Secondary malignancy of the thyroid occurs infrequently and mainly originates from malignant tumors kidney, gastrointestinal tract, lungs, breast, skin. The correct diagnosis is important but difficult. Importantly, there are major differences in treatment primary metastatic cancer, which has a significant impact on prognosis survival. Therefore, how to diagnose metastasis (TM) correctly before surgery concern for surgeons.We report 38-year-old woman who presented with palpable cervical...

10.12998/wjcc.v8.i4.838 article EN World Journal of Clinical Cases 2020-02-25

The present study aimed to detect serum levels of three phthalate esters in polycystic ovary syndrome (PCOS) patients and explore the association between these PCOS. Eighteen PCOS 16 age-matched women without or laparoscopy-proven endometriosis but with infertility related tubal defects pelvic adhesions were recruited into study. Serum (diethyl [DEP], dibutyl [DBP] diisooctyl [DEHP]) measured using high performance liquid chromatography. Results showed had significantly higher DEP DBP than...

10.5897/sre10.918 article EN Scientific Research and Essays 2011-03-31

Objective To explore the effect of 5-ethynyl-2'-deoxyuridine (EdU) -labeled adipose-derived stem cells (ADSCs) on lung colonization, TNF-α and IL-4 in rats induced by lipopolysaccharide (LPS) with acute injury. Methods Thirty male Sprague-Dawley (SD) were randomly divided into normal control group (n=10), LPS model LPS+ADSCs intervention (n=10). The ALI intraperitoneally injected 8 mg/kg LPS, 4 mL/kg physiological saline, intravenously 300 μL ADSCs tail vein after 30 minutes for...

10.3760/cma.j.issn.1671-0282.2018.11.010 article EN Zhonghua jizhen yixue zazhi 2018-11-10
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