A5100337686- Cervical Cancer and HPV Research
- Reproductive tract infections research
- Reproductive System and Pregnancy
- Influenza Virus Research Studies
- Genital Health and Disease
- Bone fractures and treatments
- Hepatitis B Virus Studies
- Bladder and Urothelial Cancer Treatments
- Shoulder Injury and Treatment
- Endometrial and Cervical Cancer Treatments
- Acute Ischemic Stroke Management
- Shoulder and Clavicle Injuries
- Respiratory viral infections research
- Gut microbiota and health
- Urinary and Genital Oncology Studies
- Trauma Management and Diagnosis
- Reproductive Physiology in Livestock
- Adolescent Sexual and Reproductive Health
- Cancer-related molecular mechanisms research
- Helicobacter pylori-related gastroenterology studies
- Venous Thromboembolism Diagnosis and Management
- Adipokines, Inflammation, and Metabolic Diseases
- Pregnancy and preeclampsia studies
- Congenital Heart Disease Studies
- Pregnancy-related medical research
Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2025
Longhua Hospital Shanghai University of Traditional Chinese Medicine
2025
Shanghai University of Traditional Chinese Medicine
2025
Tianjin Medical University General Hospital
2015-2024
China-Japan Friendship Hospital
2009-2024
Jiangnan University
2019-2024
Lanzhou University Second Hospital
2024
Second Affiliated Hospital of Dalian Medical University
2019-2024
82th Hospital of Pla
2024
Lanzhou University
2024
The first case of 2009 pandemic influenza A (H1N1) virus infection in China was documented on May 10. Subsequently, persons with suspected cases and contacts those were tested. Persons whom confirmed hospitalized quarantined, some them closely observed for the purpose investigating nature duration disease.During June 2009, we 426 infected who quarantined 61 hospitals 20 provinces. Real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) testing used to confirm infection, clinical...
Background. Influenza A(H7N9) viruses isolated from humans show features suggesting partial adaptation to mammals. To provide insights into the pathogenesis of H7N9 virus infection, we compared risk factors, clinical presentation, and progression patients hospitalized with H7N9, H5N1, 2009 pandemic H1N1 (pH1N1) infections.
The heavy metal cadmium (Cd) is a contaminant widely distributed in the food chain. In present study, 8-week oral administration of probiotic strain, Lactobacillus plantarum CCFM8610, markedly decreased blood Cd levels volunteers. Further animal study showed that three L. strains administered orally exhibited significantly different effects on regulation bile acid (BA) metabolism and excretion mice. Among strains, CCFM8610 most significant enhancing hepatic BA synthesis, biliary glutathione...
Current uptake of HPV vaccination and screening in China is far below World Health Organization 2030 targets for cervical cancer elimination. We quantified health economic losses delaying large-scale implementation China.
To evaluate the diagnostic accuracy of 2011 International Federation for Cervical Pathology and Colposcopy (IFCPC) colposcopic terminology.The clinicopathological data 2262 patients who underwent colposcopy from September 2012 to 2016 were reviewed. The findings, impression, cervical histopathology analyzed. Correlations between variables evaluated using as gold standard.Colposcopic diagnosis matched biopsy in 1482 (65.5%), weighted kappa strength agreement was 0.480 (P<0.01). Colposcopic...
Patients with schizophrenia (SCZ) experience constipation at significantly higher rates compared the general population. This relationship suggests a potential genetic overlap between these two conditions. We analyzed genome-wide association study (GWAS) data for both SCZ and using five-part approach. The first second parts assessed overall local correlations methods such as linkage disequilibrium score regression (LDSC) heritability estimation from summary statistics (HESS). third part...
Qingwei San (QWS), one of classic Chinese Medicine prescripts, has been widely used to treat stomach heat syndrome which manifests oral ulcer (OU), periodontitis and upper gastrointestinal bleeding for seven hundred years. However, the therapeutic effects QWS on diabetic OU subjected are still ambiguous. In study, we investigated pharmacological mechanisms.The main components aqueous extract were analyzed by LC-MS, potential pathways targeting predicted network pharmacology. The db/db mice...
<b><i>Aims:</i></b> Aerobic vaginitis (AV) is a newly defined clinical entity which may interfere with women's reproductive health and have negative effects on pregnancy. This study was to identify the risk factors for AV. <b><i>Methods:</i></b> Participants in this case-control included healthy women All participants completed standardized questionnaire covering sociodemographic factors, sexual behaviors, personal hygiene habits behaviors....
The purpose of this study was to verify the value metagenomic next-generation sequencing (mNGS) in detecting pathogens causing acute spinal infection by reviewing results mNGS 114 patients.A total patients were included from our hospital. Samples (tissue/blood) sent for detection, and remaining samples microbiology laboratory pathogen culture, smear, histopathological analysis, other tests. Patients' medical records reviewed determine their rates time needed, guidance antibiotic treatment...
Objective: The distribution of human papillomavirus (HPV) genotypes varies by countries and regions.Data regarding HPV genotype for women with cervical intraepithelial neoplasia 2/3 (CIN2/3) are still limited.This study aimed to investigate the CIN2/3 in Shanxi province, China.Methods: Prior testing/genotyping resulted from histologic diagnosis were retrospectively collected between August 2011 2016.Results: A total 1387 a included this study.The average age was 45.7 years time period...
Influenza, an acute respiratory infection caused by influenza virus, is one of public concerns to human health. Epidemiologically, characterized a sudden outbreak and rapid transmission with varying epidemics, seasonality, high morbidity yet low case fatality (usually 0.003% 0.03% except for avian flu). The past 300 years has witnessed at least six global pandemics, including four in the 20th century -- three them originated China.
ABSTRACT Interleukin-18 (IL-18) is an important cytokine involved in innate and acquired immunity. In this study, we cloned the full-length chicken IL-18 (ChIL-18) gene from specific-pathogen-free (SPF) embryo spleen cells provided evidence that ChIL-18 a recombinant plasmid was successfully expressed DT40 cells. significantly enhanced gamma interferon (IFN-γ) mRNA expression splenocytes, which increased IFN-γ-induced nitric oxide (NO) synthesis by macrophages. The potential genetic adjuvant...
To identify factors for predicting residual or recurrent cervical intraepithelial neoplasia (CIN) after conization with negative margins. A total of 172 patients histologically verified high‐grade squamous lesions who underwent margins were recruited at the General Hospital Tianjin Medical University from December 2006 to January 2016. Follow‐up comprised clinical examination, a liquid‐based cytology test, human papillomavirus (HPV) DNA genotyping colposcopy assessment, and if indicated,...