Mélissa Parny

ORCID: 0000-0003-4024-6585
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About
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Research Areas
  • Pesticide Exposure and Toxicity
  • Genomics, phytochemicals, and oxidative stress
  • Research on Leishmaniasis Studies
  • Essential Oils and Antimicrobial Activity
  • Reproductive System and Pregnancy
  • Probiotics and Fermented Foods
  • Muscle metabolism and nutrition
  • Immune cells in cancer
  • Glutathione Transferases and Polymorphisms
  • Complement system in diseases
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Adipose Tissue and Metabolism
  • Polysaccharides and Plant Cell Walls
  • Seaweed-derived Bioactive Compounds
  • Antimicrobial Peptides and Activities
  • Antifungal resistance and susceptibility
  • Protein Hydrolysis and Bioactive Peptides
  • Traditional and Medicinal Uses of Annonaceae
  • Cancer, Hypoxia, and Metabolism
  • Peroxisome Proliferator-Activated Receptors
  • Eosinophilic Esophagitis
  • Ethnobotanical and Medicinal Plants Studies
  • Eicosanoids and Hypertension Pharmacology
  • Mosquito-borne diseases and control

Université Toulouse III - Paul Sabatier
2020-2024

Inserm
2015-2024

Centre National de la Recherche Scientifique
2023-2024

Université de Toulouse
2021-2023

École Nationale Vétérinaire de Toulouse
2023

RESTORE
2023

Pharmacochimie et Pharmacologie pour le Développement
2020-2022

Institut de Recherche pour le Développement
2020-2022

Centre Universitaire Jean-François-Champollion
2020

Lille Inflammation Research International Center
2019

Abstract Obesity and type 2 diabetes are becoming a global sociobiomedical burden. Beige adipocytes emerging as key inducible actors putative relevant therapeutic targets for improving metabolic health. However, in vitro models of human beige adipose tissue currently lacking hinder research into this cell biotherapy development. Unlike traditional bottom‐up engineering approaches that aim to generate building blocks, here scalable system is proposed pre‐vascularized functional organoids...

10.1002/advs.202301499 article EN cc-by Advanced Science 2023-09-20

Particular interest is now given to the potential of dietary supplements as alternative non-pharmacological approaches in intestinal inflammation handling. In this aim, study evaluates efficiency fish collagen peptides, Naticol®Gut, on colonic inflammation.Wild type and Mannose receptor-deficient myeloid lineage C57BL/6 mice were administered with Dextran Sodium Sulfate (DSS), DSS, Naticol®Gut or only water for 4 8 days. Inflammatory status was evaluated by establishing macroscopic...

10.1007/s00394-021-02787-7 article EN cc-by European Journal of Nutrition 2022-01-08

Background Ovarian adenocarcinoma (OVAD) frequently metastasizes to the peritoneal cavity and manifests by formation of ascites, which constitutes a tumor-promoting microenvironment. In cavity, two developmentally, phenotypically functionally distinct macrophage subsets, immunocompetent large macrophages (LPM) immunosuppressive small (SPM), coexist. Because peroxisome proliferator-activated receptor γ (PPARγ) is critical factor participating in differentiation cooperates with CCAAT/enhancer...

10.1136/jitc-2023-007031 article EN cc-by-nc Journal for ImmunoTherapy of Cancer 2023-08-01

Platelets play an important role in the innate immune response. During candidaemia, circulating fungal polysaccharides, including chitin, are released into bloodstream and can interact with platelets induce modulation of platelet activities. However chitin has not been investigated. The aims present study were to assess effect on activation, adhesion, aggregation receptor expression their impact host defence against Candida albicans. pre-treated different concentrations (10‒200 µg/mL)...

10.3389/fcimb.2019.00383 article EN cc-by Frontiers in Cellular and Infection Microbiology 2019-11-12

The disparity of harvesting locations can influence the chemical composition a plant species, which could affect its quality and bioactivity. Terminalia albida is widely used in traditional Guinean medicine whose activity against malaria has been validated vitro murine models. present work investigated antimalarial properties two samples T. collected from different Guinea.

10.1186/s12906-021-03231-3 article EN cc-by BMC Complementary Medicine and Therapies 2021-02-15

Abstract Macrophages are the main effector cells during Leishmania infection. They contribute to detection and elimination of spp. may also promote parasite resilience. Here, we report that activation transcription factor Nrf2 in macrophages plays a pivotal role progression infantum infection by controlling inflammation redox balance macrophages. We highlight involvement NOX2/ROS axis early subsequently PGE2/EP2r signalling sustainment upon L. Moreover, establish macrophage-driven...

10.1101/2023.09.15.557964 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2023-09-18
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