Naoki Nakano

ORCID: 0000-0003-4067-9233
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About
Contact & Profiles
Research Areas
  • Total Knee Arthroplasty Outcomes
  • Orthopaedic implants and arthroplasty
  • Orthopedic Infections and Treatments
  • Knee injuries and reconstruction techniques
  • Hip disorders and treatments
  • Shoulder Injury and Treatment
  • Lower Extremity Biomechanics and Pathologies
  • Bone fractures and treatments
  • Osteoarthritis Treatment and Mechanisms
  • Musculoskeletal synovial abnormalities and treatments
  • Mesenchymal stem cell research
  • Sports injuries and prevention
  • Orthopedic Surgery and Rehabilitation
  • Cardiac Valve Diseases and Treatments
  • Rheumatoid Arthritis Research and Therapies
  • Periodontal Regeneration and Treatments
  • Chronic Lymphocytic Leukemia Research
  • Diabetic Foot Ulcer Assessment and Management
  • Advanced materials and composites
  • Tendon Structure and Treatment
  • Stroke Rehabilitation and Recovery
  • Hip and Femur Fractures
  • Cancer-related gene regulation
  • Cervical and Thoracic Myelopathy
  • Chemokine receptors and signaling

Kobe University
2015-2025

Kobe University Hospital
2024

Kobe Institute Of Computing
2023-2024

John Wiley & Sons (United States)
2023

Kindai University
2014-2022

Harasanshin Hospital
2018-2021

Cambridge University Hospitals NHS Foundation Trust
2016-2020

Addenbrooke's Hospital
2016-2019

Panasonic (Japan)
2003

Nitobe Memorial Nakano General Hospital
1988

10.32098/mltj.03.2016.18 article EN Muscles Ligaments and Tendons Journal 2019-01-01

The anterior cruciate ligament (ACL) does not heal spontaneously after injury, and ACL patients of different ages respond differently to treatment. Although ACL-derived CD34-positive cells contribute bone-tendon healing reconstruction, the relationship between potential a patient's age is unknown.ACL-derived from young will have greater effect on maturation integration in an immunodeficient rat model reconstruction compared with derived older patients.Controlled laboratory study.Sixty...

10.1177/0363546514561436 article EN The American Journal of Sports Medicine 2015-01-02

Aims This study aimed to evaluate the accuracy of implant placement with robotic-arm assisted total hip arthroplasty (THA) in patients developmental dysplasia (DDH). Methods The analyzed a consecutive series 69 who underwent THA between September 2018 and December 2019. Of these, 30 had DDH were classified according Crowe type. Acetabular component alignment 3D positions measured using pre- postoperative CT data. absolute differences cup position compared non-DDH patients. Moreover, these...

10.1302/2046-3758.1010.bjr-2021-0095.r1 article EN cc-by-nc-nd Bone and Joint Research 2021-09-30

Abstract Aims Bone marrow mononuclear cells (BM-MNCs) are a rich source of hematopoietic stem that have been widely used in experimental therapies for patients with various diseases, including fractures. Activation angiogenesis is believed to be one the major modes action BM-MNCs; however, essential mechanism by which BM-MNCs activate remains elusive. This study aimed demonstrate promote bone healing enhancing through direct cell-to-cell interactions via gap junctions, addition previously...

10.1093/stmcls/sxae090 article EN other-oa Stem Cells 2025-01-23

This study examined the impact of preoperative Coronal Plane Alignment Knee (CPAK) classification on intraoperative soft tissue balance and postoperative clinical outcomes in patients undergoing modified kinematically aligned (mKA) mechanically (MA) total knee arthroplasty (TKA). A 90 knees treated with mKA-TKA 63 MA-TKA were classified based CPAK. After adjusting for confounding factors, balance, including varus/valgus joint component gap, range motion (ROM), 2011 Society Score (KSS),...

10.1055/a-2542-2583 article EN The Journal of Knee Surgery 2025-02-20

Rheumatoid arthritis (RA) involves synovial tissue proliferation, inflammation, and angiogenesis, contributes to joint destruction. Angiogenesis is a key therapeutic target for the treatment of RA, Janus kinase (JAK) inhibitors have emerged as promising therapy. In this study, we compared inhibitory effects five JAK inhibitors, including tofacitinib (TOF), baricitinib, peficitinib, upadacitinib, filgotinib, on interleukin (IL)-6-induced inflammation in RA tissues. All effectively suppressed...

10.1038/s41598-025-94894-2 article EN cc-by-nc-nd Scientific Reports 2025-03-21

Abstract Objectives This multicentre retrospective study aimed to evaluate differences in drug continuation rates and efficacy between first- second-line use of biological disease-modifying antirheumatic drugs (bDMARDs) Janus kinase inhibitors (JAKi) after failure the initial therapy real-world rheumatoid arthritis (RA) settings. Methods Data from an observational registry patients with RA Japan were analysed, encompassing 5,900 treatment courses (4,046 bDMARD/JAKi-naïve cases 1,854 s-line...

10.1093/rheumatology/keaf157 article EN Lara D. Veeken 2025-03-20

Abstract Introduction The amount of change in coronal alignment by unicompartmental knee arthroplasty (UKA) is important when considering its long-term results. This study investigated whether the mechanical hip-knee-ankle (mHKA) angle medial fixed-bearing UKA can be predicted based on arithmetic (aHKA) angle, an indicator bony nature that independent soft tissue balance. Materials and methods research involved 101 patients (125 knees) who underwent with spacer-block technique. Pre-...

10.1007/s00402-025-05892-y article EN cc-by Archives of Orthopaedic and Trauma Surgery 2025-04-26

This study aimed to examine the prosthetic orientations, limb alignment, intraoperative soft tissue balance, and early clinical outcomes associated with use of relatively new handheld robot technique compared those conventional alignment guide for bi-cruciate stabilized total knee arthroplasty (TKA).This retrospective cohort orientation 35 patients who underwent TKA using robotic assistance (robot group) a (control group). The coronal femoral component (FCA), tibial (TCA), hip-knee-ankle...

10.1007/s00264-023-05737-6 article EN cc-by International Orthopaedics 2023-03-17

No study has examined the possible factors associated with different characteristics of stem-like cells derived from anterior cruciate ligament (ACL) remnants. And purpose is to elucidate whether demographic are healing potential ACL remnants tissue. Thirty-six were harvested patients who received primary arthroscopic reconstruction. Interval injury surgery, age, sex, and combined meniscal or chondral injuries analyzed. Cells isolated remnant tissues their was evaluated by: 1)...

10.1186/s12891-015-0855-0 article EN cc-by BMC Musculoskeletal Disorders 2015-12-01
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