Hongmei Guo

ORCID: 0000-0003-4082-7363
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About
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Research Areas
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Sulfur-Based Synthesis Techniques
  • Radical Photochemical Reactions
  • Ophthalmology and Eye Disorders
  • Vestibular and auditory disorders
  • Speech Recognition and Synthesis
  • S100 Proteins and Annexins
  • Speech and Audio Processing
  • Glaucoma and retinal disorders
  • Supercapacitor Materials and Fabrication
  • Music and Audio Processing
  • Catalytic C–H Functionalization Methods
  • Synthesis and Catalytic Reactions
  • Neonatal Respiratory Health Research
  • Food composition and properties
  • Advanced Sensor and Energy Harvesting Materials
  • Oral microbiology and periodontitis research
  • Bone Tissue Engineering Materials
  • Radioactive element chemistry and processing
  • Advanced Photocatalysis Techniques
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Radioactive contamination and transfer
  • Radioactivity and Radon Measurements
  • Pediatric health and respiratory diseases

China Telecom (China)
2024-2025

China Telecom
2024-2025

National Institute for Radiological Protection
2023-2025

Shandong University
2018-2024

Wuhan University of Science and Technology
2024

Huazhong University of Science and Technology
2021-2024

Taiyuan University of Technology
2014-2024

Shanxi Academy of Medical Sciences
2023-2024

Shanxi Medical University
2023-2024

Nanjing Medical University
2024

Macrophage M1 polarization plays a pivotal role in inflammatory diseases. Progranulin (PGRN) has potential anti-inflammation action, however, the effect of PGRN on macrophage been poorly studied. Our study aimed to investigate lipopolysaccharide (LPS)-induced and clarify underlying mechanisms.RAW264.7 cells were polarized by LPS with or without recombinant (rPGRN) tumor necrosis factor alpha antibody (anti-TNF-α). A cell counting kit-8 assay (CCK-8), flow cytometry, Quantitative Real-Time...

10.1186/s12865-020-00355-y article EN cc-by BMC Immunology 2020-06-05

Abstract The delivery of alkyl radicals through photocatalytic deoxygenation primary alcohols under mild conditions is a so far unmet challenge. In this report, we present one-pot strategy for deoxygenative Giese reaction with electron-deficient alkenes, by using xanthate salts as alcohol-activating groups radical generation visible-light photoredox in the presence triphenylphosphine. convenient and high reactivity sequential C–S/C–O bond homolytic cleavage enable efficient primary,...

10.1038/s41467-021-25702-4 article EN cc-by Nature Communications 2021-09-10

A visible light-driven photocatalytic generation of sulfonamidyl radicals, and application to intramolecular alkene hydroamination, has been accomplished.

10.1039/c7cc09871e article EN Chemical Communications 2018-01-01

In this report, we identify xanthate salts as a unique class of visible-light-excitable alkyl radical precursors that act simultaneously strong photoreductants and sources. Upon direct photoexcitation anions, efficient deoxygenative alkenylation alkylation wide range primary, secondary, tertiary alcohols have been achieved via one-pot protocol, avoiding any photocatalysts. This method exhibits broad substrate scope good functional group tolerance, enabling late-stage functionalization...

10.1021/acs.orglett.2c00889 article EN Organic Letters 2022-04-25

Progranulin (PGRN), a multifunctional growth factor, plays indispensable roles in the regulation of cancer, inflammation, metabolic diseases, and neurodegenerative diseases. Nevertheless, its immune regulatory role periodontitis is insufficiently understood. This study attempts to explore effects PGRN on macrophage polarization microenvironment.

10.1186/s12967-024-05214-7 article EN cc-by Journal of Translational Medicine 2024-04-30

To investigate the association between triglyceride glucose (TyG) index and all-cause cause-specific mortality in middle age elderly population.A total of 9,254 participants with ≥ 45 years were enrolled from National Health Nutrition Examination Survey cycle 1999-2014. The TyG was determined as ln [fasting triglycerides (mg/dL) x fasting (mg/dL)/2]. Primary outcomes (cardiovascular diseases malignant neoplasms). levels risk explored Cox regression models. After a median follow-up 7.6 years,...

10.1186/s12877-022-03155-8 article EN cc-by BMC Geriatrics 2022-05-28

The rapid bioassay method for measuring actinides in human urine samples using ICP-MS/MS is suitable the assessment of internal exposure doses radiological and nuclear emergencies.

10.1039/d4ja00279b article EN Journal of Analytical Atomic Spectrometry 2025-01-01

10.1109/icassp49660.2025.10888193 article EN ICASSP 2022 - 2022 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP) 2025-03-12

Abstract An efficient and practical approach towards phosphine oxides phosphonates has been successfully developed through the desulfonative coupling of various sulfones with secondary phosphites. This protocol features simple experimental procedures under mild conditions (i. e., catalyst‐ oxidant‐free, room temperature open to air). By doing so, a variety alkynyl, alkenyl allyl or can be produced in generally good reaction efficiency selectivity (31 examples, up 98% yield). magnified image

10.1002/adsc.201700886 article EN Advanced Synthesis & Catalysis 2017-09-18

There has been a surge in the research on magnesium (Mg) alloys as promising selection for biomaterials application. However, foremost drawback, fast degradation of Mg limits its clinical use. In this study, series Sr-HA coatings with Sr content ranging between 10-100% were prepared alloys, order to control and enhance osteoblast response. Microstructure analysis indicated formation Ca10-x x (PO4)6(OH)2 thickness 28-35 μm. The results suggested that an increase led decreasing rate coated Mg....

10.1039/c9ra02210d article EN cc-by-nc RSC Advances 2019-01-01

A green solvent, high activity and selectivity present advantages of hydrogenation in supercritical conditions catalyzed by a Pd/M-AC catalyst.

10.1039/c5ra14284a article EN RSC Advances 2015-01-01

Single-crystalline NbSe<sub>2</sub>nanosheet arrays were synthesized<italic>via</italic>a CVD method. The based photodetectors show very high responsivity and external quantum efficiency to UV light.

10.1039/d0ce01140a article EN CrystEngComm 2020-01-01

This study aimed to investigate the prevalence of hyperhomocysteinemia (Hhcy) and its major determinants in Chinese urban population with new-onset hypertension.A total 574 adults (404 men 170 women) newly diagnosed primary hypertension were recruited from seven communities Nanjing, China. Data on lifestyle factors, such as physical activities, current smoking drinking status, dietary habits, familial factors collected interviews, laboratory examinations performed by well-trained personnel....

10.1080/10641963.2017.1403621 article EN Clinical and Experimental Hypertension 2017-11-27

A mild and general strategy for the direct generation of alkoxy radicals from simple aliphatic alcohols enabled by visible-light-induced photoredox/persistent radical cation dual catalysis is developed.

10.1039/d2qo00528j article EN Organic Chemistry Frontiers 2022-01-01

Summary The effects of superfine milling treatments on the thermal, pasting, morphological and structural characteristics common buckwheat starch were studied. results showed that could change structure granules. Superfine decreased relative crystallinity destroyed crystal particles starch. was 0.00% after 4 h ultrafine treatment. There is no obvious endothermic melting peak in After milling, light transmittance, swelling power solubility increased, while PV, TV FV values decreased....

10.1111/ijfs.14899 article EN International Journal of Food Science & Technology 2020-11-13

The regenerated silk fibroin is developed to soft graphene aerogels for application in stress sensor. resultant aerogel owns a low density of 14.1 mg cm −3 with high mass specific capacitance 128.4 F g −1 . When single serving as elastic medium, supercapacitive sensor established offer sensitivity 0.73 kPa ranging 0.01–10 kPa. In contract, the based on original just shows 0.04 Further, sensing stability optimized can retain 87% under constant pressure intensity 1 1000 cycles. effect be...

10.1149/1945-7111/ac34cb article EN Journal of The Electrochemical Society 2021-10-29
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