A5032440061- Particle physics theoretical and experimental studies
- Quantum Chromodynamics and Particle Interactions
- High-Energy Particle Collisions Research
- Neutrino Physics Research
- Medical Imaging Techniques and Applications
- Dark Matter and Cosmic Phenomena
- Black Holes and Theoretical Physics
- Particle Detector Development and Performance
- Particle Accelerators and Free-Electron Lasers
- Radiation Detection and Scintillator Technologies
- Atomic and Subatomic Physics Research
- Superconducting Materials and Applications
- Radiation Therapy and Dosimetry
- Computational Physics and Python Applications
- Advanced Radiotherapy Techniques
- Advanced X-ray and CT Imaging
- Advanced MRI Techniques and Applications
- Stochastic processes and statistical mechanics
- Nuclear physics research studies
- Magnetic confinement fusion research
- Advanced NMR Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Particle accelerators and beam dynamics
- Cosmology and Gravitation Theories
- Distributed and Parallel Computing Systems
Centre National de la Recherche Scientifique
2013-2024
Université Paris-Saclay
2015-2024
Inserm
2017-2024
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2015-2024
Laboratoire d’Imagerie Biomédicale
2022-2024
Institut d'Imagerie Biomédicale
2015-2024
CEA Paris-Saclay
2016-2024
CEA Grenoble
2023
CEA Cadarache
2023
Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé
2017-2019
Interaction cross sections and charged pion spectra in p+C interactions at 31 GeV/c were measured with the large acceptance NA61/SHINE spectrometer CERN SPS. These data are required to improve predictions of neutrino flux for T2K long baseline oscillation experiment Japan. A set collected during first run 2007 an isotropic graphite target a thickness 4% nuclear interaction length was used analysis. The inelastic production 257.2 +- 1.9 8.9 mb 229.3 9.0 mb, respectively. Inclusive negatively...
Spectra of positively charged kaons in p+C interactions at 31 GeV/c were measured with the NA61/SHINE spectrometer CERN SPS. The analysis is based on full set data collected 2007 a graphite target thickness 4% nuclear interaction length. Interaction cross sections and pion spectra already using same data. These new measurements combination published ones are required to improve predictions neutrino flux for T2K long baseline oscillation experiment Japan. In particular, knowledge kaon...
SPECT quantification is important for dosimetry in targeted radionuclide therapy (TRT) and the calibration of images a crucial stage image quantification. The current standardized protocol (MIRD 23) uses phantom acquisitions to derive global factor specific conditions. It thus requires every clinical protocols. We proposed an alternative complementary image-based method that allows determine adapted each patient, radionuclide, acquisition may also be used as additional independent...
This article presents a physics-informed deep learning method for the quantitative estimation of spatial coordinates gamma interactions within monolithic scintillator, with focus on Positron Emission Tomography (PET) imaging. A Density Neural Network approach is designed to estimate 2-dimensional photon interaction in fast lead tungstate (PbWO4) scintillator detector. We introduce custom loss function inherent uncertainties associated reconstruction process and incorporate physical...
The CaLIPSO project aims to develop a high precision brain-scanning PET device with time-of-flight capability. proposed uses an innovative liquid, the TriMethyl Bismuth, as detection medium. It detects simultaneously ionization and optical signals from 511 keV gamma conversion. In this paper we present design, Monte Carlo simulation, tests results for prototype. prototype demonstrated ability detect efficiently low number of photons produced by relativistic electron conversion through...
The foreseen CaLIPSO positron emission tomography (PET) scanner is dedicated to brain imaging. With its new detection technology, it expected yield simultaneously a fine spatial resolution of about 1 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> , and low image noise thanks time-of-flight with coincidence resolving time 150 ps. In this paper, we present the results GATE Monte Carlo simulations full PET "cube" geometry. estimated...
We discuss a possible explanation of the structures observed in two-particle correlations nucleus-nucleus collisions. An anomalous evolution two-dimensional angular with centrality Au-Au collisions is at collision energies sNN=62 and 200 GeV RHIC definite transition points, related to centralities. New structures, elongated rapidity localized azimuth, appear above these critical centralities, which correspond same transverse particle density. In this report, we study phenomena using...
Gadolinium nanoparticles (Gd-NP) combined with radiotherapy are investigated for radiation dose enhancement in treatment. Indeed, NPs concentrated a tumor could enhance its radiosensitization. The noninvasive quantification of the NP concentration is crucial task treatment planning and post-treatment monitoring as it will determine absorbed dose. In this work, we evaluate achievable accuracy vivo SPECT-based Gd-NP organ on rats.Gd-NPs were labeled 111In radionuclide. SPECT images have been...
The Digitizer Unit plays an important role in modeling using Geant4 Application for Tomographic Emission (GATE), a Geant4-based platform used numerical simulations medical imaging and radiotherapy. It simulates the response of photodetection components sequence analytical semi-analytical models. was written first version GATE approximately 20 years ago. Since then, it has parts grown code that can be hardly maintained. Some were unused or duplicated; some functionalities not working anymore....
This article presents a physics-informed deep learning method for the quantitative estimation of spatial coordinates gamma interactions within monolithic scintillator, with focus on Positron Emission Tomography (PET) imaging. A Density Neural Network approach is designed to estimate 2-dimensional photon interaction in fast lead tungstate (PbWO4) scintillator detector. We introduce custom loss function inherent uncertainties associated reconstruction process and incorporate physical...
The GATE toolkit (GEANT4 Application for Tomographic Emission) is a GEANT4-based (GEometry ANd Tracking) platform Monte Carlo simulations in medical physics. applications can be divided into two main axes: radiation-based imaging and radiotherapy/dosimetry. accurate modeling of the first one crucial system design optimization as well development refinement image analysis algorithms. importance precise simulation second essential characterisation external beam radiotherapy (proton therapy...
The aim of the CaLIPSO project (French acronym for Liquid Ionization Calorimeter, Scintillation Position Organometallic) is to develop proof concept a new gamma detector Positron Emission Tomography (PET) scanner small animals and human brain imaging. objective achieve spatial resolution about 1 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> without losing efficiency with respect current PET systems. Moreover, excellent time...
Anomalous centrality evolution of two-particle angular correlations observed in Au-Au collisions at √ s NN = 62 and 200 GeV the onset ridge structures are considered model interacting quark-gluon strings.We assume that given energy nucleus-nucleus critical density may be reached specific centrality.In a string percolation this might treated equivalently to formation large cluster strings characterized by density, with size comparable whole area interaction two nuclei.This hypothesis allows...
Experimental data on the onset of a so-called anomalous J/psi suppression in PbPb collisions at SPS are considered framework string percolation model. This is observed certain collision centrality, characterized by number nucleons-participants (Npart) related to impact-parameter. Modified Bjorken formula calculations performed for local energy densities AA different impact-parameters and with detailed account latest available charged particles midrapidity. Finally we compare variations mean...
Detailed study of centrality dependence low-p_t manifestation so-called "near-side ridge" phenomenon is reported recently by STAR for all charged hadrons with p_t>0.15 GeV/c from AuAu collisions at 62 and 200 GeV RHIC[1]. It indicating the existence energy-dependent point where some sudden changes in correlation pattern are observed. In present work we use hypothesis string percolation phase transition description onset this ridge. One may assume that formation rather large "macroscopic"...
The foreseen CaLIPSO Positron Emission Tomography (PET) scanner is expected to yield simultaneously a fine image resolution, about 1 mm$^3$, and high contrast. In this paper we present results of simulations for the full PET with "cube" geometry. We quantify by resolution Noise Equivalent Count Rates compare them performance most efficient clinically used scanner, High-Resolution Research Tomograph Siemens. bring up issues reconstruction spatial resolution. also simulated brain images...