A5046053994- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracerebral and Subarachnoid Hemorrhage Research
- Stroke Rehabilitation and Recovery
- Medical Imaging Techniques and Applications
- Venous Thromboembolism Diagnosis and Management
- Peripheral Neuropathies and Disorders
- Autoimmune Neurological Disorders and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Spinal Hematomas and Complications
- Vascular Malformations Diagnosis and Treatment
- Spinal Dysraphism and Malformations
- Herpesvirus Infections and Treatments
- Barrier Structure and Function Studies
- Glioma Diagnosis and Treatment
- Neurosurgical Procedures and Complications
- Cervical and Thoracic Myelopathy
- Advanced X-ray and CT Imaging
- Brain Metastases and Treatment
- Infectious Diseases and Tuberculosis
- MRI in cancer diagnosis
- Cardiac Imaging and Diagnostics
- Intracranial Aneurysms: Treatment and Complications
- Hepatocellular Carcinoma Treatment and Prognosis
Université Claude Bernard Lyon 1
2018-2024
Inserm
2022-2024
Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé
2022-2024
Centre National de la Recherche Scientifique
2019-2024
Hospices Civils de Lyon
2018-2024
Hôpital Pierre Wertheimer
2021-2024
Olea Medical (France)
2023
Hôpital Lyon Sud
2022
Lyon College
2022
Automation and Process Engineering Laboratory
2019
The aim of this study was to investigate the relationship between baseline blood-brain barrier (BBB) permeability and kinetics circulating inflammatory markers in a cohort acute ischemic stroke (AIS) patients treated with mechanical thrombectomy.
After radiochemotherapy, 30% of patients with early worsening MRI experience pseudoprogression (Psp) which is not distinguishable from progression (EP). We aimed to assess the diagnostic value radiomics in suspected EP or Psp.Radiomics features (RF) 76 (53 and 23 Psp) retrospectively identified were extracted conventional based on four volumes-of-interest. Subjects randomly assigned into training validation groups. Classification model (EP versus consisted a random forest algorithm after...
Purpose The aim of this study was to determine the minimum acquisition time without decreasing lesion detectability bone SPECT using a whole-body cadmium-zinc-telluride camera. Methods Patients referred for were retrospectively included. 30 patients reframed from native data (16 s/projection) produce 10-, 5-, and 3-s/projection sets. A “critical” time/projection defined as that below which quality becomes insufficient interpretation, determined by 3 reviewers 4-point scale (0 = 1 average, 2...
Abstract We evaluated the reproducibility of 123 I-ioflupane ( I-FP-CIT) SPECT with shorter scan times using a CZT camera. One hundred ninety-nine I-FP-CIT scans obtained standard time (30 minutes) were truncated to provide 24-, 18-, and 15-minute study simulations. Striatal binding ratios automatically calculated remained stable for all series. At 15 minutes, only 10 398 striata (2.5%) showed statistically significant different striatal compared reference These series reviewed by 2...
<h3>BACKGROUND AND PURPOSE:</h3> Early identification of the etiology spontaneous acute intracerebral hemorrhage is essential for appropriate management. This study aimed to develop an imaging model identify cavernoma-related hematomas. <h3>MATERIALS METHODS:</h3> Patients 1–55 years age with (≤7 days) were included. Two neuroradiologists reviewed CT and MR data assessed characteristics hematomas, including their shape (spherical/ovoid or not), regular irregular margins, associated...
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare immune-mediated neuropathy for which there no clearly identified risk factor. The present study variants in the FBXO38 gene three familial cases of CIDP with response to corticosteroids generations incomplete penetrance, and an unrelated fourth case diffuse nerve hypertrophy. may be involved regulation immunity mediated by CD8 T cells, have important role pathophysiology, through PD1 degradation. Considering these...
Abstract Background Herpes simplex virus encephalitis (HSE) frequently triggers secondary anti- N -methyl- d -aspartate receptor (NMDARE), but markers predicting the occurrence of this entity (HSE-NMDARE) are lacking. Methods We conducted a retrospective description patients with HSE-NMDARE diagnosed between July 2014 and August 2022 compared them to both regular forms HSE NMDARE. Results Among 375 NMDARE, 13 were included. The median age was 19 years (0.5–73), 4/13 (31%) children < 4...
The objective of this study was to assess the relationship between blood biomarkers inflammation and lesion growth within penumbra in acute ischemic stroke (AIS) patients treated with mechanical thrombectomy (MT).The HIBISCUS-STROKE cohort enrolled admitted Lyon Stroke Center for an anterior circulation AIS MT after brain MRI assessment. Lesion assessed on day 6 using a voxel-based nonlinear coregistration method dichotomized into low high according median value. C-reactive protein,...
Embolic stroke of undetermined source (ESUS) accounts for up to 25% ischemic strokes. Identification biomarkers that could improve the prediction subtype and subsequently prevention still remains a major issue.The HIBISCUS-STROKE cohort includes patients with large vessel occlusion treated mechanical thrombectomy following admission magnetic resonance imaging. Presence length susceptibility sign (SVS) were assessed by gradient-recalled echo T2*-weighted Matrix metalloproteinase-9 (MMP-9) was...
To evaluate the performance of three MR perfusion software packages (A: RAPID; B: OleaSphere; and C: Philips) in predicting final infarct volume (FIV).This cohort study included patients treated with mechanical thrombectomy following an admission MRI undergoing a follow-up MRI. Admission MRIs were post-processed by to quantify ischemic core deficit (PDV). Automatic package outputs (uncorrected volumes) collected corrected expert. Successful revascularization was defined as modified...
Abstract Purpose Iodine 123-radiolabeled 2β-carbomethoxy-3β-(4-iodophenyl)- N -(3-fluoropropyl) nortropane ( 123 I-FP-CIT) SPECT can be performed to distinguish degenerative forms of movement disorders/parkinsonism/tremor from other entities such as idiopathic tremor or drug-induced parkinsonism. For equivocal cases, semi-quantification and comparison reference values are a necessary addition visual interpretation I-FP-CIT scans. To overcome the challenges multi-center recruitment scanning...
Gadolinium nanoparticles (Gd-NP) combined with radiotherapy are investigated for radiation dose enhancement in treatment. Indeed, NPs concentrated a tumor could enhance its radiosensitization. The noninvasive quantification of the NP concentration is crucial task treatment planning and post-treatment monitoring as it will determine absorbed dose. In this work, we evaluate achievable accuracy vivo SPECT-based Gd-NP organ on rats.Gd-NPs were labeled 111In radionuclide. SPECT images have been...