Schohraya Spahis

ORCID: 0000-0003-4130-4994
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Diet, Metabolism, and Disease
  • Fatty Acid Research and Health
  • Liver Disease Diagnosis and Treatment
  • Metabolism, Diabetes, and Cancer
  • Cholesterol and Lipid Metabolism
  • Pancreatic function and diabetes
  • Diet and metabolism studies
  • Birth, Development, and Health
  • Nutrition and Health in Aging
  • Cancer, Lipids, and Metabolism
  • Endoplasmic Reticulum Stress and Disease
  • Lipid metabolism and disorders
  • Diabetes Treatment and Management
  • Digestive system and related health
  • Drug Transport and Resistance Mechanisms
  • Adipose Tissue and Metabolism
  • Phytochemicals and Antioxidant Activities
  • Infant Nutrition and Health
  • Child Nutrition and Water Access
  • Antioxidant Activity and Oxidative Stress
  • Clinical Nutrition and Gastroenterology
  • Peroxisome Proliferator-Activated Receptors
  • Attention Deficit Hyperactivity Disorder
  • Advanced Glycation End Products research
  • Inflammatory Bowel Disease

Université de Montréal
2016-2025

Centre Hospitalier Universitaire Sainte-Justine
2015-2024

Université Laval
2015-2022

Art Research Centre of the Slovak Academy of Sciences
2019

McGill University
2017

Université Claude Bernard Lyon 1
2017

Hôpital Edouard Herriot
2017

Hadassah Medical Center
2014

Canadian Nutrition Society
2007

Although several clinical trials have evaluated the impact of n-3 polyunsaturated fatty acid (PUFA) on patients with attention-deficit hyperactivity disorder (ADHD), changes in plasma PUFA composition were not always assessed following supplementation. Furthermore, no reports are available efficacy Canadian youth ADHD.To determine (FA) composition, and safety supplementation ADHD symptoms French primary school children.The Strengths Weaknesses Normal Behaviors (SWAN) Conners' questionnaires...

10.1093/pch/14.2.89 article EN Paediatrics & Child Health 2009-02-01

Cystic fibrosis (CF)-related diabetes (CFRD) has become a critical complication that seriously affects the clinical outcomes of CF patients. Although CFRD emerged as most common nonpulmonary CF, little is known about its etiopathogenesis. Additionally, whether oxidative stress (OxS), feature and diabetes, influences pathophysiology requires clarification. The main objective this study was to shed light on role cystic transmembrane conductance regulator (CFTR) in combination with OxS insulin...

10.1152/ajpendo.00333.2015 article EN AJP Endocrinology and Metabolism 2015-12-02

Background Arachidonic acid (AA; C20∶4 n-6) and docosahexaenoic (DHA; C22∶6 n-3) are important long-chain polyunsaturated fatty acids (LC-PUFA) in maintaining pancreatic beta-cell structure function. Newborns of gestational diabetic mothers more susceptible to the development type 2 diabetes adulthood. It is not known whether low circulating AA or DHA involved perinatally "programming" this susceptibility. This study aimed assess concentrations AA, other associated with fetal insulin...

10.1371/journal.pone.0085054 article EN cc-by PLoS ONE 2014-01-13

The role of AMPK in regulating energy storage and depletion remains unexplored the intestine. This study will to define its status, composition, regulation lipid function, as well examine impact insulin resistance type 2 diabetes on intestinal activation, sensitivity, metabolism. Caco-2/15 cells Psammomys obesus (P. obesus) animal models were experimented. We showed predominance AMPKα1 prevalence α1/β2/γ1 heterotrimer cells. activation by 5-aminoimidazole-4-carboxamide ribonucleoside...

10.1210/en.2013-1750 article EN Endocrinology 2014-01-14

Understanding the specific mechanisms of rare autosomal disorders has greatly expanded insights into complex processes regulating intestinal fat transport. Sar1B GTPase is one critical proteins governing chylomicron secretion by small intestine, and its mutations lead to retention disease, despite presence Sar1A paralog.The central aim this work examine cause-effect relationship between expression output determine whether obligatory for normal high-density lipoprotein biogenesis.The SAR1B...

10.1161/atvbaha.117.310121 article EN Arteriosclerosis Thrombosis and Vascular Biology 2017-10-06

Genetic defects in SAR1B GTPase inhibit chylomicron (CM) trafficking to the Golgi and result a huge intraenterocyte lipid accumulation with failure release CMs liposoluble vitamins into blood circulation. The central aim of this study is test hypothesis that deletion (SAR1B-/- ) disturbs enterocyte homeostasis (e.g., FA β-oxidation lipogenesis) while promoting oxidative stress inflammation. Another issue compare impact SAR1B-/- its paralogue SAR1A-/- combined /B-/- To address these critical...

10.1194/jlr.ra119000119 article EN cc-by Journal of Lipid Research 2019-08-13

COVID-19 represents a novel infectious disease induced by SARS-CoV-2. It has to date affected 24,240,000 individuals and killed 2,735,805 people worldwide. The highly virus attacks mainly the lung, causing fever, cough, fatigue in symptomatic patients, but also pneumonia severe cases. However, growing evidence highlights SARS-CoV-2-mediated extrarespiratory manifestations, namely, gastrointestinal (GI) hepatic complications. detection of 1) GI system (duodenum, colon, rectum, anal region,...

10.1152/ajpgi.00106.2021 article EN AJP Gastrointestinal and Liver Physiology 2021-05-19

Abstract Background Weight bias and stigmatization are highly prevalent in modern society, especially educational settings, such as universities. Despite extensive documentation of the adverse consequences on students’ daily functioning psychological health, there is limited literature regarding factors associated with weight its extent Quebec Objectives This exploratory study aims to assess prevalence experiences weight-related stigmatization, well examine their associations gender, health...

10.1186/s12889-025-21922-1 article EN cc-by BMC Public Health 2025-02-19

Metabolic syndrome (MetS) constitutes a spectrum of interconnected conditions comprising obesity, dyslipidemia, hypertension, and insulin resistance (IR). While singular, all-encompassing treatment for MetS remains elusive, an integrative approach involving tailored lifestyle modifications emerging functional food therapies holds promise in preventing its multifaceted manifestations. Our main objective was to scrutinize the efficacy cranberry proanthocyanidins (PAC, 200 mg/kg/day 12 weeks)...

10.3390/antiox14030268 article EN cc-by Antioxidants 2025-02-26

Gestational diabetes mellitus is a common complication of pregnancy. Long-chain polyunsaturated fatty acids (LCPUFA) are essential for fetal neurodevelopment. Docosahexaenoic acid (DHA) the predominant n-3 LCPUFA in brain and retina. Circulating absolute concentrations total n-6 LCPUFAs rise during normal It remains unclear whether gestational may affect circulating third trimester pregnancy - period rapid This study aimed to address this question.In prospective singleton cohort, fasting...

10.1111/dme.12978 article EN Diabetic Medicine 2015-10-03
Coming Soon ...