A5100680090- Advanced Image and Video Retrieval Techniques
- Video Surveillance and Tracking Methods
- Robotics and Sensor-Based Localization
- Immune Cell Function and Interaction
- Advanced Vision and Imaging
- Immune Response and Inflammation
- Video Analysis and Summarization
- Industrial Vision Systems and Defect Detection
- Image and Object Detection Techniques
- T-cell and B-cell Immunology
- Ocular Infections and Treatments
- Image Enhancement Techniques
- Chronic Lymphocytic Leukemia Research
- Visual Attention and Saliency Detection
- Lymphoma Diagnosis and Treatment
- Infrared Target Detection Methodologies
- Cancer-related Molecular Pathways
- Cellular transport and secretion
- Manufacturing Process and Optimization
- Xenotransplantation and immune response
- Aquaculture disease management and microbiota
- Antimicrobial Peptides and Activities
- Atherosclerosis and Cardiovascular Diseases
- Cancer, Lipids, and Metabolism
- Cell death mechanisms and regulation
Nanjing Drum Tower Hospital
2010-2025
Shanxi Medical University
2024
Shanghai Polytechnic University
2010-2024
Shaanxi Provincial People's Hospital
2024
Sichuan Normal University
2024
State Key Laboratory of Biotherapy
2023
Sichuan University
2021-2023
Jiangsu Province Hospital
2013-2022
Nanjing Medical University
2013-2022
Anhui Medical University
2022
In recent years, there has been an increasing number of related studies on exosomes. Most have focused exosomes derived from mammals, confirming the important role that play in cell communication. Plants, as a natural ingredient, plant-derived confirmed to similar structures and functions mammalian-derived Plant-derived exosome-like nanoparticles (PELNs) are lipid bilayer membrane nanovesicles containing bioactive constituents such miRNA, mRNA, protein, lipids obtained plant cells, can...
Abstract Pseudomonas aeruginosa , a common nosocomial pathogen, relies on siderophores to acquire iron, crucial for its survival in various environments and during host infections. However, understanding the molecular mechanisms of siderophore regulation remains incomplete. In this study, we found that BfmRS two-component system, previously associated with biofilm formation quorum sensing, is essential under high osmolality stress. Activated BfmR directly bound promoter regions pvd, fpv...
Fish cell cultures are becoming more widely used models for investigating molecular mechanisms of physiological response to environmental challenge. In this study, we derived two immortalized Mozambique tilapia (Oreochromis mossambicus) lines from brain (OmB) and lip epithelium (OmL), compared them a previously bulbus arteriosus (TmB) line. The OmB OmL were generated without or with Rho-associated kinase (ROCK) inhibitor/3T3 feeder layer supplementation. Although both approaches successful,...
Prunella vulgaris L. has been an important medicinal plant for the treatment of thyroid gland malfunction and mastitis in China over 2000 years. There is urgent need to select effective wavelengths greenhouse cultivation P. as light a very factor growth. Here, we described effects natural (control) UV solar exclusion on morphological physiological traits, secondary metabolites contents antioxidant activities vulgaris. The results showed that resulted remarkable alterations biomass traits;...
Currently, unresectable esophageal squamous cell carcinoma (ESCC) is primarily treated by chemoradiotherapy. However, the outcome has not improved significantly due to radioresistance of cancer cells. This study aimed determine radiosensitizing effect LCL161, a novel second mitochondrial-derived activator caspase (Smac) mimetic, in ESCC lines were with LCL161 or radiation, alone combination. Cell proliferation was detected MTT assay. Radiosensitization evaluated clonogenic survival apoptosis...
Survivin is overexpressed in cancer cells and plays a crucial role apoptosis evasion. YM155, small-molecule inhibitor of survivin, could enhance the cytotoxicity various DNA-damaging agents. Here, we evaluated radiosensitizaion potential YM155 human esophageal squamous cell carcinoma (ESCC).Cell viability was determined by CCK8 assay. The radiosensitization effect clonogenic survival progression tumor xenograft. Cell cycle flow cytometric analysis. Radiation-induced DNA double strand break...
To study the expression of toll-like receptors (TLRs) in healthy corneas and with active or nonactive herpetic stromal keratitis (HSK).Eight HSK (including 5 3 cases) 8 were evaluated for TLR1-10 mRNA by reverse transcription-polymerase chain reaction (RT-PCR) relative real-time PCR. The proteins TLR2, 9 different groups, also compared immunofluorescence staining. data analyzed SPSS 11.5.TLR1-10 was expressed both corneas. In cornea, TLR1, 2, 3, 4, 6 higher, whereas TLR7, 8, lower to TLR 10....
The high-mobility group box 1 (HMGB1) protein plays an important role in a lot of biological behaviors, including DNA damage repair, gene transcription, cell replication, and death, its expression is higher many solid tumors tissues than their adjacent normal tissues, it always involved tumor proliferation, metastasis, therapeutic tolerance, poor prognosis. However, HMGB1 proliferation radioresistance esophageal squamous carcinoma (ESCC) remains poorly understood. In this study, the effect...
Vascular calcification is related to many diseases. Iron has a certain relationship with endothelial cells and vascular calcification. The purpose of this study was assess the effect iron overload on cell mechanisms through experiments.Human umbilical vein were treated different concentrations FeSO4 (50, 100, 150, 200 µM), deferoxamine (DFO) ferrostatin. Alkaline phosphatase activity, malondialdehyde (MDA) level, reactive oxygen species (ROS) lipid superoxidation after treatment assessed....
Skin and soft tissue infections are common because of exposure to aquatic environment, while severe caused by Aeromonas veronii rare.We report a case skin infection the left upper limb veronii. A 50-year-old Chinese woman, who had history cardiac disease type 2 diabetes mellitus, accidentally injured her thumb cutting fish. Early antibiotic therapy surgical debridement was performed before result bacterial culture came back. Whole-genome sequencing further confirm pathogen reveal drug...
The future of the endangered red panda (Ailurus fulgens) depends in part on development protective measures against infectious diseases. present study is a first step toward improved understanding diseases species' home regions. Serum samples obtained from 73 pandas 10 captive facilities southwest, east, and northeast China October to December 2004 were tested for antibodies nine common pathogens carnivores. Antibody titers canine distemper virus (CDV), parvovirus (CPV), adenovirus (CAV)...
Photothermal therapy (PTT) is a promising antitumor treatment that easy to implement, minimally invasive, and precisely controllable, evokes strong immunity. We believe thorough elucidation of its underlying immune mechanisms would contribute the rational design combination treatments with other strategies consequently potentiate clinical use. In this study, PTT using indocyanine green (ICG) induced STING-dependent type I interferon (IFN) production in macrophages (RAW264.7 bone...
Thermoelectric cooler has dynamic thermoelectric performance under complex environment. A model of is derived using small-signal linearization method. It shows that the one zero and two poles. The shown to vary with different operating condition. Based on average linear a cooler, temperature control system designed for cold end adaptive NN-PID algorithm. step response tests show controller satisfying steady performance. In room environment, time cooling down 10□ around 70s error very small....
Background: Psoriasis is a common immune-mediated hyperproliferative skin dysfunction with known genetic predisposition. Gene-gene interaction (e.g., between HLA-C and ERAP1) in the psoriasis context has been reported various populations. As ERAP1 recognized as susceptibility gene plays critical role antigen presentation, we performed this study to identify interactions other variants. Methods: We validated variants an independent cohort of 5,414 patients 5,556 controls. Multifactor...
This paper proposes a visual-infrared image registration method based on sparse representation using Scale Invariant Features Transform (SIFT) features. Firstly, obtain the inverse of infrared image, enhance visible and through Brightness Preserving Bi-Histogram Equalization (BPHE), extract SIFT feature points descriptors. Then, descriptors is represented by images, find initial matches l1 minimization. RANSAC adopted to filter out mismatches. Finally, optimize transform parameters an...