A5052811232- Nutrition and Health in Aging
- Frailty in Older Adults
- Heart Failure Treatment and Management
- Vestibular and auditory disorders
- Cardiovascular and exercise physiology
- Body Composition Measurement Techniques
- Hearing, Cochlea, Tinnitus, Genetics
- Health Systems, Economic Evaluations, Quality of Life
- Ear Surgery and Otitis Media
- Cardiovascular Function and Risk Factors
- Ophthalmology and Eye Disorders
- Hearing Loss and Rehabilitation
- Meningioma and schwannoma management
- Glaucoma and retinal disorders
- Hip and Femur Fractures
- Tracheal and airway disorders
- Balance, Gait, and Falls Prevention
- Dysphagia Assessment and Management
- Ear and Head Tumors
- Peripheral Artery Disease Management
- Cardiac Health and Mental Health
- Esophageal and GI Pathology
- Diagnosis and treatment of tuberculosis
- Blood Pressure and Hypertension Studies
- GDF15 and Related Biomarkers
Sakakibara Hospital
2015-2025
Izumi City General Hospital
2021-2024
Kindai University
2004-2019
Hiroshima University
2019
University of Tsukuba
1979-2009
Kyoto Katsura Hospital
2009
Kyoto University
2009
Kanazawa Institute of Technology
2009
Nara Institute of Science and Technology
2009
Fukui Prefectural Hospital
1961-1995
Abstract Aims Sarcopenia, one of the extracardiac factors for reduced functional capacity and poor outcome in heart failure (HF), may act differently between HF with preserved ejection fraction (HFpEF) (HFrEF). We sought to investigate impact sarcopenia on mortality HFpEF HFrEF. Methods results performed a post hoc analysis multicentre prospective cohort study, including 942 consecutive older (age ≥65 years) hospitalized patients: 475 (ejection ≥45%, age 81 ± 7 years, 48.8% men) 467 HFrEF...
Abstract Background The purpose of this study was to clarify the prevalence, association with frailty and exercise capacity, prognostic implication sarcopenic obesity in patients heart failure. Methods present included 779 older adults hospitalized failure (median age: 81 years; 57.4% men). Sarcopenia diagnosed based on guidelines by Asian Working Group for Sarcopenia. Obesity defined as percentage body fat mass (FM) obtained bioelectrical impedance analysis. FM cut-off points were 38% women...
Background Frailty is conceptualized as an accumulation of deficits in multiple areas and strongly associated with the prognosis heart failure (HF). However, social domain frailty less well investigated. We prospectively evaluated clinical characteristics prognostic impact (SF) elderly patients HF. Methods Results FRAGILE-HF (prevalence value physical geriatric hospitalized for failure) a multicenter, prospective cohort study focusing on HF aged ≥65 years. defined SF by Makizako's 5 items,...
Although evidence suggests that cognitive decline and physical frailty in elderly patients with heart failure (HF) are associated prognosis, the impact of concurrent impairment, is, frailty, on prognosis has yet to be fully investigated. The current study sought investigate prevalence prognostic HF.This is a sub-analysis FRAGILE-HF, prospective multicentre observational involving aged ≥65 years hospitalized for HF. Fried criteria Mini-Cog were used diagnose respectively. association between...
Cachexia substantially impacts the prognosis of patients with heart failure (HF); however, there is no standard method for cachexia diagnosis. This study aimed to investigate association Evans's criteria, consisting multiple assessments, HF in older adults.This a secondary analysis data from FRAGILE-HF study, prospective multicentre cohort that enrolled consecutive hospitalized aged ≥65 years HF. Patients were divided into two groups: and non-cachexia groups. was defined according criteria...
Although frailty is strongly associated with mortality in patients heart failure (HF), the risk of which specific cause death being complicated unclear. We aimed to clarify association between multidomain and causes elderly hospitalized HF.
ABSTRACT Background The Asian Working Group for Cachexia (AWGC) proposed a new definition of cachexia; however, its impact on cachexia prevalence and overlaps with other conditions, such as sarcopenia malnutrition, are unclear. We investigated these aspects the prognostic value based AWGC mortality in older patients heart failure (HF). Methods This study was secondary analysis prospective multicentre cohort, namely, FRAGILE‐HF cohort study. Older (≥ 65 years) who had been hospitalized due to...
Abstract Aims The benefits of exercise in patients with heart failure are well documented. However, to date, the association between habits and prognosis is yet be evaluated. In this study, we investigated pre-hospital post-discharge older adult failure. Methods This post-hoc analysis utilised data from FRAGILE-HF which included 1,262 aged ≥ 65 years who required hospitalisation for decompensation. Exercise before were assessed through a three-question physical activity assessment tool....
Abstract Frailty is a common comorbidity associated with adverse events in patients heart failure, and early recognition key to improving its management. We hypothesized that the AST ALT ratio (AAR) could be marker of frailty failure. Data from FRAGILE-HF study were analyzed. A total 1327 aged ≥ 65 years hospitalized failure categorized into three groups based on their AAR at discharge: low (AAR < 1.16, n = 434); middle (1.16 ≤ 1.70, 487); high 406). The primary endpoint was one-year...
Abstract Aims Functional decline due to skeletal muscle abnormalities leads poor outcomes in patients with acute heart failure (AHF). The 6-minute walking test (6MWT) reliably evaluates functional capacity, but its technical difficulty for the elderly often limits benefits. Although Short Physical Performance Battery (SPPB) is a comprehensive measure of physical performance, role AHF remains unclear. This study aimed examine prognostic significance SPPB compared 6MWT hospitalized AHF....
Abstract Aims Frailty is highly prevalent and associated with poor prognoses in elderly patients heart failure (HF). However, the potential effects of physical frailty on benefits HF medications are unclear. We aimed to determine influence prognosis reduced mildly ejection fraction (HFr/mrEF). Methods results From combined database FRAGILE‐HF Kitasato cohorts, hospitalized a left ventricular < 50% age ≥ 65 years were analysed. Patients treated or without renin‐angiotensin‐aldosterone...
This study aimed to investigate the prevalence, clinical characteristics, and prognostic value of bendopnea in older patients hospitalized for heart failure.
Social factors encompass a broad spectrum of nonmedical factors, including objective (social isolation [SI]) and perceived (loneliness) conditions. Although social have attracted considerable research attention, information regarding their impact on patients with heart failure is scarce. We aimed to investigate the prognostic SI loneliness in older failure.
We used ocular vestibular evoked myogenic potentials to investigate the relationship between residual dizziness and utricular function following canalith repositioning procedure for benign paroxysmal positional vertigo.Ocular were measured in 44 patients (40 included analyses, four excluded) with successful results from procedure. The examined before treatment again one week after treatment. analyzed how various general factors related dizziness.Residual was not gender, affected side, age,...
There have been no investigations of the prevalence and clinical implications coexistence anaemia frailty in older patients hospitalized with heart failure (HF) despite their association adverse health outcomes. The present study was performed to determine prognostic value HF. We post hoc analysis consecutive HF ≥65 years old enrolled FRAGILE-HF, which prospective, multicentre, observational study. Anaemia defined as haemoglobin < 13 g/dL men <12 women, evaluated according Fried phenotype...
Abstract Aims Although aging is strongly associated with both heart failure and a decline in gait speed, definition of slowness incorporating an age‐related has yet to be developed. We aimed define event‐driven cut‐off for the relative speed against age‐adjusted reference values derived from general population evaluate its prognostic implications. Methods results Standardized (SGS) was defined as median stratified by age, sex, height 3777 elderly (age ≥ 65 years) individuals without history...
In heart failure (HF), inflammation is linked to malnutrition and impaired physical function. this study, we aimed assess how novel nutritional-inflammatory markers lymphocyte-to-C-reactive protein ratio (LCR) score (LCS) are associated with the nutritional status, function, prognosis of patients HF.