A5011639580- Viral gastroenteritis research and epidemiology
- Wnt/β-catenin signaling in development and cancer
- Brain Tumor Detection and Classification
- AI in cancer detection
- Advanced Combustion Engine Technologies
- Virus-based gene therapy research
- Cancer-related gene regulation
- Advanced Chemical Physics Studies
- Respiratory viral infections research
- Combustion and flame dynamics
- Spectroscopy and Laser Applications
- RNA Research and Splicing
- Combustion and Detonation Processes
- Developmental Biology and Gene Regulation
- Atmospheric chemistry and aerosols
- Gas Sensing Nanomaterials and Sensors
- Dementia and Cognitive Impairment Research
- Plasma Applications and Diagnostics
- Functional Brain Connectivity Studies
- Energetic Materials and Combustion
- Animal Virus Infections Studies
- Catalytic Processes in Materials Science
- Mercury impact and mitigation studies
- Ubiquitin and proteasome pathways
- Cancer, Hypoxia, and Metabolism
Fujian Medical University
2025
Shanghai Jiao Tong University
2018-2023
Shanghai University of Electric Power
2021-2023
State Key Laboratory of Mechanical System and Vibration
2022
Shanghai First People's Hospital
2018-2022
Center for Excellence in Molecular Cell Science
2021
Chinese Academy of Sciences
2003-2021
Guangdong Academy of Sciences
2019-2021
Institute of Microbiology
2019-2021
Kunming University of Science and Technology
2020-2021
Abstract Homeobox A10 (HOXA10) has been implicated critical for the promotion of carcinogenesis, but underlying mechanism between HOXA10 and malignant gastric cancer (GC) phenotype remains elusive. In present study, we analyzed validated that BCL2 expressions were elevated both at mRNA protein levels in GC tissues. Upregulated promoted cell proliferation with reduced apoptosis vitro accelerated tumor growth vivo. Bioinformatics analysis quantitative real‐time polymerase chain reaction...
Abstract The results of a cDNA array revealed that protocadherin gamma subfamily A, 9 (PCDHGA9) was significantly decreased in SGC-7901 gastric cancer (GC) cells compared with GES-1 normal and strongly associated the Wnt/β-catenin transforming growth factor-β (TGF-β)/Smad2/3 signaling pathway. As member cadherin family, PCDHGA9 functions both cell–cell adhesion nuclear signaling. However, its role tumorigenicity or metastasis has not been reported. In present study, we found GC tissues...
Gastric cancer (GC) is a very aggressive malignant tumor of the digestive system. Previous studies have shown that N-acetyltransferase 10 (NAT10) can regulate N4-acetylcytidine (ac4C) modification downstream mRNAs through certain pathways to promote progression various tumors. However, reports on regulatory effects NAT10 GC are rare. This study aimed explore potential mechanism by which regulated progression. Clinical samples were used correlation between expression and poor prognosis in...
Gastric cancer (GC) is one of the most common cancers causing a poor prognosis worldwide. HOXA13, as member homeobox (HOX) family, involved in regulation progression and has attracted increasing attention, potential novel target for anticancer strategies. However, significance HOXA13 GC remains unclear. This article aims to explore mechanism progression.Quantitative real-time PCR was carried out detect expression FN1 correlation between tissues. In vitro assays were conducted investigate...
Abstract Background Human noroviruses are one of the main causes foodborne illnesses and represent a serious public health concern. Rapid sensitive assays for human norovirus detection undoubtedly necessary clinical diagnosis, especially in regions without more sophisticated equipment. Method The rapid reverse transcription recombinase-aided amplification (RT-RAA) is fast, robust isothermal nucleic acid method based on enzyme reaction. This can complete sample at 39 °C 30 min. In this study,...
Tryptophan 2,3-dioxygenase (TDO), encoded by the gene TDO2, is an enzyme that catalyses first and rate-limiting step of tryptophan (Try) degradation in kynurenine (Kyn) pathway liver. Recently, TDO has been demonstrated to be expressed various human tumours, especially hepatocellular carcinoma (HCC). However, role HCC still not very clear. Here, we studied HCC.We overexpressed tissues significantly correlated with malignant phenotype characteristics, including tumour size, differentiation,...
HOXA13 is a transcription factor of the Homeobox (HOX) gene family, which highly evolutionarily conserved. upregulated and associated with oncogenic properties in some cancers. Here, we studied potential mechanism HOXA13-mediated proliferation metastasis gastric cancer (GC).Quantitative real-time PCR, Western blot, immunohistochemistry were used to detect expression levels GC. In vitro vivo assays performed investigate function GC cell proliferation, migration, invasion. RNA-Seq...
Abstract Cesium lead iodide (CsPbI 3 ) has attracted a great deal of attention as an absorption layer material for perovskite solar cells (PSCs) with high stability and suitable band gap (1.72 eV). In response to the problems defect‐induced nonradiative compounding voltage loss caused by common layer, strategies interfacial engineering, altering crystal equivalence, other modifications involve more complex processes higher fabrication costs. order simplify process save costs, this work...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTShock Tube Study of the Reaction between CH3 and H2H. J. Baeck, K. S. Shin, H. Yang, Z. Qin, V. Lissianski, W. C. Gardiner Jr.Cite this: Phys. Chem. 1995, 99, 43, 15925–15929Publication Date (Print):October 1, 1995Publication History Published online1 May 2002Published inissue 1 October 1995https://pubs.acs.org/doi/10.1021/j100043a034https://doi.org/10.1021/j100043a034research-articleACS PublicationsRequest reuse permissionsArticle...
Early detection, diagnosis and treatment of Alzheimer's Disease (AD) is currently the most effective way to delay progression disease. Among various neuroimaging techniques for AD, resting-state magnetic resonance imaging (rs-fMRI) able measure neurological activity brain non-invasively without radiation, has become an important tool studying neurodegenerative diseases. The functional network established by rs-fMRI data offers possibility quantitatively elucidate changes associated with...
Chemoresistance remains a major challenge in the therapy of gastric cancer (GC). The homeobox (HOX) gene family has gained attention carcinogenesis and chemoresistance. Here, this study aimed to explore mechanism HOXA13 GC chemoresistance.Quantitative real-time PCR (qRT-PCR) Western blot were used evaluate expression tissues. Kaplan-Meier plotter database was mined for prognosis analysis patients with different receiving 5-Fluorouracil (5-FU) therapy. effects on sensitivity cells 5-FU...
Human norovirus is regarded as the leading cause of epidemic acute gastroenteritis with GII.4 being predominant genotype during past decades. In winter 2014/2015, GII.17 Kawasaki 2014 emerged genotype, surpassing in several East Asian countries. Hence, influence host immunity response on continuous evolution different variants needs to be studied depth. Here, we relate inferences evolutionary mechanisms investigation cross-reactivity and cross-protection their respective antisera using...
Human norovirus is a common cause of acute gastroenteritis worldwide, and oysters have been found to be the main carriers for its spread. The lack efficient pre-treatment methods has major bottleneck limiting detection viruses in oysters. In this study, we established novel immunomagnetic enrichment method using polyamidoamine (PAMAM) dendrimer/SA-biotin-mediated cascade amplification reverse transcriptase quantitative real-time polymerase chain reaction (RT-qPCR) detection. We compared...