A5026062694- Spectroscopy Techniques in Biomedical and Chemical Research
- Molecular Biology Techniques and Applications
- Spectroscopy and Chemometric Analyses
- Thyroid Cancer Diagnosis and Treatment
- Uterine Myomas and Treatments
- Photodynamic Therapy Research Studies
- Nanoplatforms for cancer theranostics
- Metabolomics and Mass Spectrometry Studies
- Machine Learning in Bioinformatics
- Ubiquitin and proteasome pathways
- Hepatitis B Virus Studies
- Cervical Cancer and HPV Research
- Cancer-related Molecular Pathways
- Animal Virus Infections Studies
- Identification and Quantification in Food
- Cancer, Hypoxia, and Metabolism
- DNA Repair Mechanisms
- Infrared Thermography in Medicine
- Graphene and Nanomaterials Applications
- Bee Products Chemical Analysis
- Tannin, Tannase and Anticancer Activities
- Genetic factors in colorectal cancer
- Sexual Differentiation and Disorders
- Nanoparticles: synthesis and applications
- Bone Tissue Engineering Materials
Universidade do Vale do Paraíba
2016-2025
Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde
2023
University of Otago
2022
Instituto do Câncer do Estado de São Paulo
2022
University of Iowa
2017
Universidade Estadual Paulista (Unesp)
2004-2012
Universidade Estadual de Campinas (UNICAMP)
2001
Universidade de São Paulo
2001
Universidade Federal de São Paulo
2001
Open reading frame expressed sequences tags (ORESTES) differ from conventional ESTs by providing sequence data the central protein coding portion of transcripts. We generated a total 696,745 ORESTES 24 human tissues and used subset that correspond to set 15,095 full-length mRNAs as means assessing efficiency strategy its potential contribution definition transcriptome. estimate sampled over 80% all highly moderately expressed, between 40% 50% rarely genes. In our most thoroughly sequenced...
Breast carcinoma (BC) corresponds to 23 % of all cancers in women, with 1.38 million new cases and 460,000 deaths worldwide annually. Despite the significant advances identification molecular markers different modalities treatment for primary BC, ability predict its metastatic behavior is still limited. The purpose this study was identify novel associated distinct clinical outcomes a Brazilian cohort BC patients. We generated global gene expression profiles using tumor samples from 24...
Nanomaterials based on graphene oxide nanoribbons (GNR) and nanohydroxyapatite (nHAp) serve as attractive materials for bone tissue engineering. Herein, we evaluated the potential of nHAp/GNR toward in vitro analysis specific genes related to osteogenesis vivo regeneration using animal model. Three different concentrations composites were analyzed a cytotoxicity assay, osteogenic was determined by ALP, OPN, OCN, COL1, RUNX2 alkaline phosphatase assays. In neoformation well-established rat...
Approximately 70% of cervical carcinoma cases show the presence high-risk Human Papilloma Virus (HPV), especially HPV-16 and HPV-18, can be used to stratify high risk patients from low healthy. Currently, molecular biology techniques such as polymerase chain reaction (PCR) are identify virus in patient samples. While methodology is highly sensitive, it labor intensive time-consuming. Alternative techniques, vibrational spectroscopy, has been suggested a possible rapid alternative. Therefore,...
Abstract Thirty thyroid samples of normal and abnormal tissues were analyzed by infrared confocal Raman Spectroscopy. We studied the Amide I (1,720–1,580 cm −1 ) spectral region in order to determine different components proteins' secondary structure samples. Peak positions bands determined using second derivative Fourier self‐deconvolution spectra. obtained band areas corresponding β‐turn, 3 10 ‐helix, α‐helix, β‐sheet, β‐turns, side chains for spectra Gaussian fitting. Using spectra, we...
Nodal status is the most significant independent prognostic factor in breast cancer. Identification of molecular markers would allow stratification patients who require surgical assessment lymph nodes from large numbers for whom this procedure unnecessary, thus leading to a more accurate prognosis. However, up now, reported studies are preliminary and controversial, although hundreds have been assessed, few them used clinical practice treatment or prognosis The purpose present study was...
Uterine leiomyomas are common, benign, smooth muscle tumors representing a significant public health problem. The aim of this study was to investigate CYP17A1, CYP19, and androgen (AR) polymorphisms, their relative risks for uterine possible associations with clinical parameters.Uterine leiomyoma tissues blood samples were obtained from 87 patients, as peripheral 68 control women. Clinical data recorded in both groups. CYP17A1 (rs743572) polymorphism analyzed by PCR-RFLP, the CYP19 [TTTA](n)...
Introduction The colorectal cancer is a major health problem worldwide. Histology considered the gold standard for differential diagnosis. However, it depends on observer's experience, which can lead to discrepancies and poor results. Spectroscopic imaging by Fourier transform infrared (FTIR) technique that may be able improve diagnosis, because based biochemical differences of structural constituents tissue. Therefore, main goal this study was explore use FTIR in normal colon tissue,...