A5101832848- Advanced X-ray Imaging Techniques
- Advanced biosensing and bioanalysis techniques
- X-ray Spectroscopy and Fluorescence Analysis
- Cancer Cells and Metastasis
- Advanced X-ray and CT Imaging
- Cancer Genomics and Diagnostics
- Advanced Electron Microscopy Techniques and Applications
- 3D Printing in Biomedical Research
- Amyotrophic Lateral Sclerosis Research
- Crystallography and Radiation Phenomena
- Microfluidic and Bio-sensing Technologies
- Nanoparticle-Based Drug Delivery
- RNA Interference and Gene Delivery
- Electrospun Nanofibers in Biomedical Applications
- DNA and Nucleic Acid Chemistry
- Neurogenetic and Muscular Disorders Research
- Medical Imaging Techniques and Applications
- Tribology and Lubrication Engineering
- Congenital heart defects research
- Digital Holography and Microscopy
- Nuclear Physics and Applications
- Hepatitis B Virus Studies
- Hydraulic and Pneumatic Systems
- Parkinson's Disease Mechanisms and Treatments
- Gear and Bearing Dynamics Analysis
JBS Science (United States)
2021-2025
Suzhou Institute of Nano-tech and Nano-bionics
2016-2025
Chinese Academy of Sciences
2016-2025
Harbin Institute of Technology
2015-2025
Ningbo University
2025
Northeast Forestry University
2025
Children's Hospital of Chongqing Medical University
2021-2025
Chongqing Medical University
2021-2025
National Clinical Research
2025
Hefei University of Technology
2016-2025
Phase sensitive X-ray imaging methods can provide substantially increased contrast over conventional absorption-based and therefore new otherwise inaccessible information. The use of gratings as optical elements in hard phase overcomes some the problems that have impaired wider radiography tomography. So far, to separate information from other contributions detected with a grating interferometer, phase-stepping approach has been considered, which implies acquisition multiple radiographic...
Single-hole hollow polymer microspheres (see Figure) have been synthesized through the direct polymerization and cross-linking reactions occurring at surface of carboxyl-capping polystyrene colloids, followed by removal core particles. The molecular imprinting these single-hole towards specific high-capacity uptake target species opens new routes to promising applications.
Protein contact map prediction is useful for protein folding rate prediction, model selection and 3D structure prediction. Here we describe NNcon, a fast reliable server software. NNcon was ranked among the most accurate residue predictors in Eighth Critical Assessment of Techniques Structure Prediction (CASP8), 2008. Both software are available at http://casp.rnet.missouri.edu/nncon.html.
Over the last decade, significant progress has been made to develop sensitive devices for capture of circulating tumor cells (CTCs) from blood cancer patients. However, simple and counting CTCs cannot provide effective information understanding biology them. In this work, a functional biointerface is fabricated specific nondestructive release samples. A nanostrucure porous network based on chitosan nanofibers by electrospinning, mimic function extracellular matrices, then poly(carboxybetaine...
Extreme rarity and inherent heterogeneity of circulating tumor cells (CTCs) result in a tremendous challenge for the CTC isolation from patient blood samples with high efficiency purity. Current approaches mainly rely on epithelial cell adhesion molecule (EpCAM), which may significantly reduce ability to capture CTCs when expression EpCAM is lost or down-regulated epithelial-mesenchymal transition. Here, rapid highly efficient method developed isolate identify heterogeneous using...
A full-field transmission X-ray microscope (TXM) operating continuously from 5 keV to 12 with fluorescence mapping capability has been designed and constructed at the Beijing Synchrotron Radiation Facility, a first-generation synchrotron radiation facility 2.5 GeV. Spatial resolution better than 30 nm demonstrated using Siemens star pattern in both absorption mode Zernike phase-contrast mode. scanning-probe integrated TXM shown provide 50 p.p.m. sensitivity for trace elements spatial...
In this work, a uniform multiscale TiO2 nanorod array is fabricated to provide "multi-scale interacting platform" for cell capture, which exhibits excellent capture specificity and sensitivity of the target cells after modification with bovine serum albumin (BSA) DNA aptamer. After studying performance BSA-aptamer substrates other nanostructured substrates, we can conclude that multisacle could indeed effectively enhance yields cancer cells. The yield artificial blood samples on up 85%–95%,...
The majority of current methods isolating circulating tumor cells (CTCs) rely on a biomarker. However, the isolation efficiency may be compromised due to heterogeneity CTCs. In this work, simple and broad-spectrum method is established efficiently isolate heterogeneous CTCs from patient blood samples using tannic acid (TA)-functionalized magnetic nanoparticles (MNPs). TA-functionalized MNPs (MNPs-TA) inhibit nonspecific adhesion peripheral mononuclear cell (PBMC) enhance cancer capture,...
Dual aptamer-modified PLGA nanofiber-based microfluidic devices were fabricated to achieve the highly efficient isolation and specific release of epithelial mesenchymal CTCs.
Fabricating an organic–inorganic nanocomposite hydrogel platform with antibacterial, anti-inflammatory, and osteoinductive properties that mimic bone extracellular matrix composition is decisive for guiding development in orthopedic practice.
A label-free optical probe was developed for Ca(2+) detection based on the aggregation-induced emission property of Au(i)-thiolate complexes. Upon incubation with Ca(2+), Au(I)-cysteine complexes rapidly aggregated through Cys-Ca(2+) interaction, resulting in a luminescent The low cost, simple design and fast response.
The luminescence intensity of the glutathione capped Au-nanoclusters could be enhanced due to formation aggregates, and was employed for visual detection Pb<sup>2+</sup>.
To investigate the genetic contribution of ANXA11, a gene associated with amyotrophic lateral sclerosis (ALS), in Chinese ALS patients and without cognitive dementia.Sequencing all coding exons ANXA11 intron-exon boundaries 18 familial (FALS), 353 unrelated sporadic (SALS), 12 ALS-frontotemporal lobar dementia (ALS-FTD). The transcripts peripheral blood generated from splicing mutation were examined by reverse transcriptase PCR.We identified 6 nonsynonymous heterozygous mutations (5 novel 1...