- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Helicobacter pylori-related gastroenterology studies
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Inflammatory Bowel Disease
- Esophageal Cancer Research and Treatment
- Dysphagia Assessment and Management
- Gastroesophageal reflux and treatments
- Microscopic Colitis
- Pancreatic and Hepatic Oncology Research
- Ovarian cancer diagnosis and treatment
- Gastrointestinal Bleeding Diagnosis and Treatment
- Colorectal Cancer Screening and Detection
- Head and Neck Cancer Studies
- Foreign Body Medical Cases
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Marine and Offshore Engineering Studies
- Salivary Gland Disorders and Functions
- Schizophrenia research and treatment
- Oral microbiology and periodontitis research
- Occupational and environmental lung diseases
- Genetic factors in colorectal cancer
- Antifungal resistance and susceptibility
Yokohama City University Medical Center
2017-2025
Yokohama City University
2017-2025
Fujisawa City Hospital
2023-2025
Obayashi (Japan)
2020
Aichi Medical University
2002
Osaka Dental University
1987
AIMTo investigated the relationship between postoperative bleeding following gastric endoscopic submucosal dissection (ESD) and individual antithrombotic agents. METHODSA total of 2488 neoplasms in 2148 consecutive patients treated May 2001 June 2016 were studied.The agents categorized into antiplatelet agents, anticoagulants, other we included combination therapies [e.g., dual therapy (DAPT)].The risk factors associated with post-ESD bleeding, namely, overall, withdrawal or continuation...
Objective We evaluated the safety and efficacy of vonoprazan-based amoxicillin clarithromycin 7-day triple therapy (VAC) in comparison to proton pump inhibitor (PPI)-based (PAC) as a first-line treatment metronidazole (VAM) PPI-based (PAM) second-line for eradication Helicobacter pylori Japan.
Qualitative diagnosis of ulcerative colitis-associated neoplasia (UCAN) is crucial for surveillance colonoscopy in patients with colitis (UC). Although the utility magnifying endoscopy narrow-band imaging (ME-NBI) sporadic has been reported, its efficacy UCAN remains unclear. This study aimed to evaluate usefulness ME-NBI qualitative UCAN. We generated 60 images (30 UCANs and 30 nonneoplasia lesions, including 10 polypoid 20 nonpolypoid lesions) from UC who underwent at our hospital between...
Abstract Objectives Although a novel submucosal injection material consisting of fully synthetic, self‐assembling peptide solution, PuraLift, has recently become commercially available in Japan, there are few reports regarding the usefulness this solution. The aim study was to investigate feasibility PuraLift for conventional endoscopic mucosal resection (EMR) clinical practice. Methods This multicenter retrospective conducted at endoscopy units five institutions from January 2023 May 2023....
Esophageal squamous cell carcinoma (ESCC) in patients with no history of tobacco smoking or alcohol consumption accounts for approximately 5% all ESCCs. This study aimed to clarify the clinicopathological features superficial ESCCs consumption. Clinical data and pathological 108 endoscopic submucosal dissection (ESD) specimens obtained from 102 (NTNA group) were reviewed. For comparison, 767 ESD 544 (TA also Factors analyzed included age, sex, synchronous/metachronous cancer,...
Clinicopathological features of early gastric cancers arising in Helicobacter pylori uninfected patients
Abstract Background and Aim Endoscopic resection is feasible for superficial tumors in patients with ulcerative colitis; however, endoscopic options have not been evaluated comprehensively. We the efficacy safety of submucosal dissection mucosal resection, decision making regarding colitis. Methods Endoscopically treated from colitis were analyzed retrospectively. en bloc R0 adverse events, local tumor recurrence, metachronous lesion occurrence rates. Results examined 102 (mean size, 12 mm;...
Endoscopic resection is recommended for non-ampullary duodenal neuroendocrine tumors (NAD-NETs) ≤10 mm in diameter and confined to the submucosal layer, without lymph node or distant metastasis. However, efficacy safety of endoscopic dissection (ESD) NAD-NET remains unclear. The aim this study was assess short-term long-term outcomes ESD NAD-NET.Eight patients with 8 NAD-NETs who underwent between 2015 2018 were included. indications were: i) tumor diameter; ii) NET G1; iii) layer; iv) We...
Background . Vonoprazan affords more clinical benefits than proton pump inhibitors (PPIs) during the healing of gastroduodenal ulcers. However, it remains controversial whether vonoprazan is effective PPIs when used to heal artificial ulcers arising after endoscopic submucosal dissection (ESD). Aim This study investigated effects compared with esomeprazole on post-ESD Methods Sixty patients who underwent gastric ESD between May 2015 and 2017 were randomized treatment (V group) or (E for 8...
Superficial nonampullary duodenal epithelial tumors (SNADETs) have become frequently detected and referred for endoscopic resection (ER). However, optimal treatment methods long-term outcomes after ER of SNADETs not been fully elucidated. We aimed to clarify them by analyzing our large cohort patients with SNADETs.We enrolled 190 consecutive from 189 undergoing between January 2004 September 2019. Cases were stratified into submucosal dissection (ESD), conventional mucosal resection, (CEMR)...
Severe submucosal fibrosis is a crucial technical difficulty encountered during endoscopic dissection (ESD) in patients with ulcerative colitis (UC). We aimed to identify predictors of severe UC.
Superficial duodenal epithelial tumors are emerging targets for endoscopic submucosal dissection (ESD). However, it is unknown how competence achieved in ESD. This study aimed to elucidate the learning curve ESD.This retrospective observational included 100 consecutive patients who underwent ESD by a single endoscopist between March 2014 and September 2021. The primary outcome was define an with sufficient non-duodenal experience. Cumulative sum (CUSUM) analysis used assess terms of...
Background and aims Endoscopic treatment of recurrent/residual colonic lesions on scars is a challenging procedure. In this setting, endoscopic submucosal dissection (ESD) considered the first choice, despite significant rate complications. full-thickness resection (eFTR) has been shown to be well-tolerated effective for these lesions. The aim study conduct comparison outcomes such between ESD eFTR in an Italian Japanese referral center. Methods From January 2018 July 2020, we...
PuraStat (3-D Matrix, Tokyo, Japan) is a novel self-assembling peptide hydrogel developed as hemostatic agent that believed to be effective in reducing the risk of delayed perforation due excessive cautery burns [1] [2] [3]. Additionally, studies animal models have suggested potential for preventing esophageal strictures after endoscopic submucosal dissection cancer [4] [5]. In this report, we present case which gel effectively managed stricture and safely addressed complications related...
Abstract Background Levodopa–carbidopa intestinal gel (LCIG) treatment, a unique drug delivery system for patients with advanced Parkinson’s disease (PD), is covered by health insurance in Japan since September 2016. Various LCIG procedure/device-associated adverse events (AEs) have been reported; however, reports on their treatment limited. This the first multicenter study to clarify frequency and timing of device-related AEs. Methods Between 2016 December 2018, 104 introduced PD 11...
We attempted to compare the antidepressant efficacy of milnacipran and fluvoxamine in 202 outpatients with major depression, using 17-item Hamilton Depression Rating Scale (HDRS). Special attention was paid difference responsiveness as a function severity depression individual HDRS factors. As result, while no significant between treatment groups found overall, positive response (50% or more decrease total score from baseline) recorded significantly often than recipients whose baseline...