Rationale: Myocardial infarction (MI) is one of the most dangerous adverse cardiovascular events. Our previous study found that lysophosphatidic acid (LPA) increased in human peripheral blood after MI, and LPA has a protective effect on survival proliferation various cell types. However, role its receptors MI less understood. Objectives: To unknown heart during MI. Methods Results: In this study, we mice also had elevated level blood, as well cardiac expression receptor 2 early stages With...

Abstract OBJECTIVES Coronary-related technical complications constantly occur during type A aortic dissection surgical repair and are potentially fatal, yet their risk factors require further investigation. The intricate morphology of coronary ostial involvement may have a substantial impact. METHODS From June 2019 to January 2024, consecutive patients who underwent open surgery were included. Patients divided into the group (non-significant involvement: Neri A-dissected intima involving...

We retrospectively analyzed 367 patients receiving surgical resection of cardiac myxomas in our center over six years, and the incidence results 28 cases right atrial myxomas. also compared age, gender, attached sites between left myxoma myxoma.Between January 2007 December 2012, with underwent resection. There were 16 males 12 females. The mean age was 47.77 ± 13.20 years (range: 8.00-79.00 years). Associated lesions included moderate severe tricuspid regurgitation four, coronary...

The total aortic arch replacement with frozen elephant trunk is increasingly being used. However, deep hypothermic circulatory arrest inevitable. We performed a novel surgical technique, the 'aortic balloon occlusion', in treatment of Stanford type A dissection to reduce adverse effects caused by arrest.

Background We sought to analyze clinical features and surgical results of 10 cases cardiac myxomas in Carney complex (CNC). Methods Between January 2003 December 2013, patients with CNC underwent resection. Associated lesions included moderate severe mitral regurgitation two cases, tricuspid one case. Age, gender, the incidence arterial embolism, rate multiple myxomas, recurrence after resections myxoma were compared between isolated CNC. Results The was 1.74% (10/574). There no deaths...

The aim of this study was to evaluate the objective outcomes type II hybrid arch repair (HAR) and total replacement with frozen elephant trunk (TAR FET).Data from 528 patients who underwent aortic January 2017 June 2019 were collected, which consisted 175 HAR 353 TAR FET. propensity score-matched analysis identified a subgroup 90 pairs. Perioperative data mid-term follow-up results assessed.There no significant difference in composite adverse events (type HAR, 20.6%, 36/175 vs FET, 17.8%,...

The goal of this study was to compare clinical outcomes double arterial cannulation (DAC), axillary and femoral in patients undergoing frozen elephant trunk for type A aortic dissection.Between 2015 2020, the included 488 divided into 3 groups: 171 DAC group, 217 group 100 group. Overall survival primary end point were analysed after inverse probability weighting.A total 43 died during follow-up period. presented higher percentages coeliac trunk, renal iliac artery malperfusion, but early...

We introduce a simple classification of the non-coronary sinus Valsalva aneurysm, and suggest different approach for corresponding type aneurysm.Between October 1996 December 2009, 45 patients with aneurysm underwent surgical repair. Twenty-three were male 22 female. The mean age was 32.80±11.77 years (range, 13-67 years). divided them into two types, I: rupture or protrusion right atrium; II: atrium ventricle near at tricuspid annulus. For I (n=32), chosen, using direct suture patch II...

Our goal was to review the surgical treatment of retrograde type A aortic dissection (RTAD) after thoracic endovascular repair (TEVAR) in our centre.From January 2014 April 2018, 22 patients with RTAD TEVAR were operated on centre. The mean age at operation 52.0 ± 8.0 years old. median interval between primary procedure and 4.6 months (range 0-120 months). postoperative mortality morbidity rates calculated evaluate early long-term results.Twenty received total arch replacement frozen...

Data on the clinical features and surgical outcomes of type A intramural hematoma (IMH) in Chinese patients are very limited. We aimed to present experiences IMH our center, report early late outcomes.From February 2012 April 2018, 106 consecutive underwent open surgery for at hospital. adopted emergent operation with cardiac tamponade or other severe complications, recommended initial medical treatment followed by elective stable patients. The composite endpoints included operative...

Abstract Background Obesity is dramatically increasing worldwide, and more obese patients may develop aortic dissection present for surgical repair. The study aims to analyse the impact of body mass index (BMI) on outcomes in with acute Stanford type A (ATAAD). Methods From January 2017 June 2019, clinical data 268 ATAAD a single centre were retrospectively reviewed. They divided into three groups based BMI: normal weight (BMI 18.5 < 25 kg/m 2 , n = 110), overweight 30 114) ≥30 44)....

The classification system of Sakakibara and Konno for sinus Valsalva aneurysm (SVA) is highly complex seldom utilized in clinical practice. In this study, we propose a new simple system; suggest novel approach that utilizes four distinct types SVAs.We retrospectively studied 257 cases SVAs which surgical repair was performed between October 1996 December 2009 divided these into types: I, rupture or protrusion the right atrium; II, atrium ventricle near at tricuspid annulus; III, ventricular...

Abstract OBJECTIVES The aim of this study was to propose and evaluate the new operative technique aortic balloon occlusion in total arch replacement (TAR) with frozen elephant trunk that can significantly decrease time circulatory arrest increase hypothermic cardiopulmonary bypass (CPB) temperature. METHODS Between 2010 2018, 1335 patients dissection who underwent TAR were included study. newest 80 cases treated occlusion. To illustrate difference procedure, 1255 conventional served as...

The optimal arterial cannulation site for acute aortic dissection repair is unclear, especially complex arch surgery. Axillary artery widely accepted but adding femoral to it was considered potentially improve perfusion and early outcomes. To clarify this point, a comparison of perioperative outcomes these two different strategies conducted regarding the pathological features dissection. From January 2010 December 2019, 927 consecutive patients underwent total replacement combined with...

The electronic absorption and vibrational spectra of deprotonated 5,10,15,20-tetrakis(p-hydroxyphenyl)porphyrin (THPP) are studied as a function solvent polarity in H

Objective: To describe and analyze the clinical characteristics, laboratory data, management outcome of patients with onconeural antibody associated disorders (OAAD) identify predictors for poor outcome. Methods: This was a retrospective review all potential OAAD, who were hospitalized in Jinan General Hospital between September 2009 July 2017. We clarified diagnosis, collected comprehensive information categorized into 3 groups: paraneoplastic neurological (PNDs), autoimmune encephalitis...

Congenital heart disease combined with lung agenesis is extremely rare. We report a case of 5-year-old female ventricular septal defect (VSD) and left severe pulmonary hypertension who underwent successful closure the VSD.

To analyze the clinical features, diagnostic strategies and therapeutic methods associated with paraneoplastic neurological syndromes.A retrospective study of syndromes was performed at a single center in Shandong, East China. The medical records follow-up data 28 patients were intensively reviewed between February 2011 December 2014.Twenty-four (85.7%) experienced subacute or chronic onset disease, most common symptoms reported mild myasthenia paresthesias. Twenty-five (89.3%) presented...