A5007915544- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pancreatic and Hepatic Oncology Research
- Medical Imaging Techniques and Applications
- Neuroendocrine Tumor Research Advances
- Pancreatitis Pathology and Treatment
- Lung Cancer Diagnosis and Treatment
- Sarcoidosis and Beryllium Toxicity Research
- Colorectal Cancer Surgical Treatments
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Respiratory and Cough-Related Research
- Abdominal vascular conditions and treatments
- Radiopharmaceutical Chemistry and Applications
- Radiomics and Machine Learning in Medical Imaging
- Genetic factors in colorectal cancer
- Gastrointestinal disorders and treatments
- Infectious Diseases and Mycology
- Antifungal resistance and susceptibility
- Colorectal and Anal Carcinomas
- Neuroblastoma Research and Treatments
- Liver Disease and Transplantation
- Eosinophilic Disorders and Syndromes
- Tracheal and airway disorders
- Ocular Infections and Treatments
Kyorin University
2022-2025
Brigham and Women's Hospital
2024
Harvard University
2024
Kyoto University
2024
Kanagawa Cardiovascular and Respiratory Center
2021-2023
National Hospital Organization Saitama Hospital
2022
Saitama Red Cross Hospital
2021-2022
Kitano Hospital
2019-2021
Fukui-ken Saiseikai Hospital
2021
Fukui Prefectural Hospital
2015-2019
Background/Objectives: Bronchoscopy is an invasive procedure, and patient coughing during the examination has been reported to cause significant distress. This study aimed identify predictors of severity assess its impact on procedure bronchoalveolar lavage (BAL) transbronchial lung biopsy (TBLB). Methods: We conducted a prospective involving 119 consecutive patients with diffuse disease who underwent BAL TBLB at Kyorin University Hospital from April 2019 December 2023. Cough was scored...
A 59-year-old man presenting with fecal occult blood visited our hospital. He was diagnosed advanced lower rectal cancer, which contiguous the prostate and left seminal vesicle. There were no metastatic lesions lymph nodes or other organs. We performed laparoscopic total pelvic exenteration (LTPE) using transanal minimal invasive surgery technique bilateral en bloc lateral node dissection for primary cancer after neoadjuvant chemoradiotherapy. The operative time 760 min, estimated loss 200...
Patients with non-small cell lung cancer (NSCLC) are often positive for oncogenic driver mutations, such as EGFR, ALK, BRAF, RET and MET exon 14 skipping mutations (METex14 skipping). Recently, METex14 has become a functional biomarker NSCLC the approval of kinase inhibitors. Tepotinib is an oral inhibitor. Its overall response rate 46%, median duration 11.1 months. In Japan, companion diagnostics tepotinib limited ArcherMET AmoyDx test, but not Oncomine Dx target test. The present study...
Objective Dexamethasone, remdesivir (REM), and baricitinib (BAR) are commonly used to treat coronavirus disease 2019 (COVID-19). High-dose steroids have also been reported be well tolerated, even when in combination with multiple drugs. In this retrospective study, we assessed the safety therapeutic efficacy of a three-drug high-dose steroids, REM, BAR hospitalized COVID-19 patients. Methods We retrospectively evaluated therapy. Patients 107 patients moderate or severe who underwent 3-drug...
Epithelioid hemangioendothelioma (EHE) affects many organs, particularly lung and liver, typically presents as multiple lesions. Treatment for EHE is not yet standardized, but surgery appropriate when lesions are resectable. In our patient, radiography revealed bilateral pulmonary nodules, CT showed several liver tumors. The masses those in the right were removed during initial surgery; pathology of hepatic specimens confirmed diagnosis EHE. During second operation, left nodules excised, all...
Background/Objectives: Acute exacerbation (AE) of interstitial lung disease (ILD) is a major challenge. This study aimed to retrospectively investigate occurrences AEs in patients with ILDs, including idiopathic pulmonary fibrosis (IPF), non-IPF (iNSIP: nonspecific pneumonia), and connective tissue (CTD)-associated ILDs (CTD-ILDs), at single tertiary center before after the coronavirus 2019 (COVID-19) pandemic. The clarify seasonal regional trends assess roles viral bacterial infections,...
目的：diverting stoma は直腸癌術後合併症の軽減のために造設されるが，その閉鎖部には新たな瘢痕創が生じるため，整容性の向上が期待される腹腔鏡手術の利点を損なう可能性がある．腹腔鏡手術において，臍創は病巣摘出のために拡大されるため，同部位にdiverting stomaを造設することで創の追加を防ぐことができると考えられた．我々は21例において臍部人工肛門を造設し，臍部人工肛門の有用性について検討した．方法：創延長を行った臍部から腸管を挙上した．挙上回腸の口側を尾側とし，脱落防止目的に筋層と固定した．口側腸管は反転固定するとともに，翻転させた臍底部をストーマ腸管の“股”部分に固定して腸管挙上の補助とした．結果：主な術後合併症は，outlet obstructionの1例のみであった．また，翻転した臍皮膚でびらんが顕著であったが，処置の工夫で管理継続は可能であった．閉鎖時は，腸管と筋組織の癒着は小範囲であった．また，閉鎖後の感染症は認めなかった．結語：臍部人工肛門は整容性に優れるのみでなく，人工肛門に関連した合併症の予防にもつながると考えられた．
症例は71歳，男性．腹痛を主訴に紹介医を受診し，腫瘍による閉塞性膵炎の診断で入院となった．ERCP施行時にVater乳頭より活動性の出血を認めたため，精査目的に当院に紹介となった．画像では膵頭部に30mm大の多血性腫瘤を認めた．貧血の進行があり，下膵十二指腸動脈に対して塞栓術を施行した．以上，膵癌疑いにて膵頭十二指腸切除，リンパ節郭清D2を施行した．切除標本の肉眼所見は4.2×2.3×2.0cmの嚢胞性腫瘤を認めた．病理組織検査では，背景は分枝膵管型IPMNから構成されていた．膵管および膵実質に浸潤する乳頭状腺癌，繊維肉腫様の細胞を認めた．以上より，分枝膵管型IPMN内に発生した膵癌肉腫と診断した．非常に稀な膵癌肉腫の1例を経験したので，若干の文献的考察を含めて報告する．
Abstract Lung or head and neck cancer have been indicated as solid cancers associated with invasive pulmonary aspergillosis (IPA), but the relationship hepatocellular carcinoma (HCC) is unknown. We report a case of HCC in which presence cirrhosis corticosteroid administration may caused development IPA.
Background/Aim: Cancer and ischemic stroke are closely associated. Thromboembolism susceptibility in lung cancer may differ depending on oncogenic alterations. However, the clinical characteristics of thromboembolism patients with BRAF-mutant non-small-cell remain unknown. Thus, this study aimed to evaluate cumulative incidence population describe such cases detail. Patients Methods: We retrospectively investigated consecutive BRAF V600E-mutant cancer. Cumulative was calculated using a...
We herein report a case of bilateral pneumothorax after unilateral transbronchial lung cryobiopsy (TBLC). A 73-year-old man with no history cardiothoracic surgery underwent TBLC for the reevaluation interstitial disease. Five hours later, he developed pneumothorax, pneumomediastinum, and subcutaneous emphysema. He chest drainage was discharged 18 days later. The biopsy specimens obtained from contained visceral pleura bronchial cartilage, suggesting injury as cause pneumothorax.
Abstract A 39 year‐old woman with malignant foot melanoma underwent wide excision of the primary tumor a safety margin and sentinel lymph node biopsy (SLNB) for right inguinal node. SLNB was positive computed tomography (CT) scan revealed iliac swelling. Positron emission (PET–CT) nodes abnormal uptake fluorodeoxyglucose (FDG). We performed laparoscopic pelvic obturator, node) dissection. During operation, several black were observed in Pathologically, consisted metastasized atypical...