A5085382676- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Advanced MRI Techniques and Applications
- Atomic and Subatomic Physics Research
- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Sarcoidosis and Beryllium Toxicity Research
- Cardiac Imaging and Diagnostics
- Medical Imaging and Pathology Studies
- Medical Image Segmentation Techniques
- Radiomics and Machine Learning in Medical Imaging
- Occupational and environmental lung diseases
- Medical Imaging Techniques and Applications
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Lung Cancer Research Studies
- Cardiovascular Function and Risk Factors
- Systemic Sclerosis and Related Diseases
- Cancer Immunotherapy and Biomarkers
- Occupational exposure and asthma
- Pulmonary Hypertension Research and Treatments
- Pleural and Pulmonary Diseases
- Inflammatory Myopathies and Dermatomyositis
- Advanced X-ray and CT Imaging
- MRI in cancer diagnosis
- Neuroendocrine Tumor Research Advances
- IgG4-Related and Inflammatory Diseases
Kanagawa Cardiovascular and Respiratory Center
2016-2025
Yokohama City University
1996-2024
Boehringer Ingelheim (Canada)
2022
Weatherford College
2022
Patients First
2022
Yokohama City University Medical Center
2021
Chiba University
2015
Society of Thoracic Surgeons
2015
Kobe University
2013
Universidade de São Paulo
2012
Section:ChooseTop of pageAbstract <<IntroductionMethodsHistorical PerspectiveEpidemiologyEtiologiesClinical Manifestations a...Lung FunctionImaging FeaturesPathology FeaturesOutcome and ComplicationsPathogenesis Putative...Terminology Definitio...Is CPFE a Syndrome?ManagementClinical Trial Perspectiv...Relevance for the...Research PrioritiesConclusionsReferencesCITING ARTICLES
Background Phase contrast ( PC ) cine‐magnetic resonance imaging MRI of the coronary sinus allows for noninvasive evaluation flow reserve CFR ), which is an index left ventricular microvascular function. The objective this study was to investigate in patients with heart failure preserved ejection fraction HF p EF ). Methods and Results We studied 25 (mean SD age: 73±7 years), 13 hypertensive hypertrophy LVH (67±10 18 controls (65±15 years). Breath‐hold cine‐ images were obtained assess blood...
Idiopathic pulmonary fibrosis (IPF) often accompanies lung cancer, and life-threatening acute exacerbation (AE) of IPF (AE-IPF) is reported to occur in 20 % patients who undergo cancer surgery. Pirfenidone an anti-fibrotic agent known reduce disease progression patients. A phase II study was conducted evaluate whether perioperative pirfenidone treatment could the incidence postoperative AE-IPF with cancer.Pirfenidone orally administered were candidates for surgery; dosed at 600 mg/day first...
Introduction Interstitial lung disease associated with primary Sjögren’s syndrome (pSS–ILD) shows several patterns such as nonspecific interstitial pneumonia (NSIP) and usual (UIP). Although UIP is a well–recognized prognostic determinant in idiopathic pneumonias, whether this also the case pSS–ILD unclear. The objectives of study were to evaluate effect UIP, identify factors pSS–ILD. Methods A retrospective review medical records identified 33 consecutive patients pathologically–proven Each...
Multidisciplinary discussion (MDD) requiring close communication between specialists (clinicians, radiologists and pathologists) is the gold standard for diagnosis of idiopathic interstitial pneumonias (IIPs). However, MDD by not always feasible because they are often separated time location. An online database would facilitate data sharing MDD. Our aims were to develop a nationwide cloud-based integrated containing clinical, radiological pathological patients with IIPs along web-based...
Abstract Background and objective Myeloperoxidase anti‐neutrophil cytoplasmic antibody (MPO‐ANCA) is occasionally positive in patients with usual interstitial pneumonia (UIP). However, the differences from idiopathic pulmonary fibrosis (IPF/UIP) have not been well documented. We aimed to clarify clinical, radiological pathological features of UIP associated MPO‐ANCA (ANCA/UIP). Methods retrospectively reviewed medical records 12 consecutive ANCA/UIP manifesting microscopic polyangiitis 108...
Rationale: A fatal acute exacerbation (AE) occasionally develops during chemotherapy for small cell lung cancer (SCLC) with comorbid idiopathic pulmonary fibrosis (IPF).Objectives: This study aimed to assess the safety and efficacy of carboplatin, etoposide, nintedanib combination therapy unresectable SCLC IPF.Methods: The NEXT-SHIP is a multicenter, single-arm, phase 2 trial IPF (Japan Registry Clinical Trials registry number jRCTs031190119). patients received (150 mg twice daily). primary...
The purpose of this study was to quantitatively evaluate paradoxical diaphragmatic motion using magnetic resonance (MR) imaging. A total 27 subjects were examined, including 12 normal young adults, six control individuals, and nine patients with emphysema. With in the supine position, 30 sequential sagittal MR images entire right lung obtained during tidal deep slow breathing. Diaphragmatic movement between estimated as displacement area a respiratory cycle calculated. diaphragm,...
Oxygen-enhanced magnetic resonance imaging (MRI) has been proposed as a useful tool for assessing regional morphological and functional changes in chronic obstructive pulmonary disease (COPD).To prospectively directly compare the efficacy of O(2)-enhanced MRI quantitative computed tomography (CT) smoking-related loss assessment clinical stage classification COPD.One hundred sixty smokers were classified into four age- gender-matched groups by using GOLD criteria smokers: Smokers without COPD...
Interstitial lung disease (ILD) is frequent complication of systemic sclerosis (SSc) and mixed connective tissue (MCTD). The heterogeneous, its outcome unpredictable. Some patients have severe progressive deterioration ILD, which the leading cause mortality. We aimed to determine whether serum levels Krebs von den Lungen-6 (KL-6) surfactant protein-D (SP-D) correlate with SSc/MCTD-associated ILD activity.We retrospectively analyzed medical records 40 ILD: 29 SSc 11 MCTD. Measurement KL-6...
ABSTRACT Introduction Anti‐neutrophil cytoplasmic antibody (ANCA) seropositivity strongly correlates to ANCA‐associated vasculitis. Patients with idiopathic interstitial pneumonias (IIPs) without systemic vasculitis are sometimes ANCA‐positive. Radiological and pathological differences between patients myeloperoxidase (MPO)‐ANCA‐positive those proteinase 3 (PR3)‐ANCA‐positive IIPs remain unclear. To determine whether high‐resolution computed tomography (HRCT) features pathology findings...
Abstract The apparent diffusion coefficient (ADC) in the optic nerve was measured from diffusion‐weighted magnetic resonance imaging using an intravoxel incoherent motion (IVIM) sequence. subjects were seven normal volunteers and eight patients with multiple sclerosis (MS) a total of four nerves acute neuritis nine chronic neuritis. mean ADC (4.18 ± 1.13 × 10 −3 mm 2 /s, n = 9) significantly higher than that (1.56 0.675 14) (0.94 0.43 /s 4) (P < 0.001). is useful assessing MS foci nerves.