A5058167202- Aquaculture Nutrition and Growth
- Nuclear Physics and Applications
- Radiation Detection and Scintillator Technologies
- Aquaculture disease management and microbiota
- Graphene research and applications
- Epilepsy research and treatment
- 2D Materials and Applications
- Advanced Neuroimaging Techniques and Applications
- Immune cells in cancer
- Cancer Immunotherapy and Biomarkers
- Medical Imaging Techniques and Applications
- Chaos-based Image/Signal Encryption
- Cell death mechanisms and regulation
- MXene and MAX Phase Materials
- Endoplasmic Reticulum Stress and Disease
- Neurological disorders and treatments
- Ferroptosis and cancer prognosis
- Cancer-related Molecular Pathways
- Telomeres, Telomerase, and Senescence
- Image and Object Detection Techniques
- Phagocytosis and Immune Regulation
- Icing and De-icing Technologies
- Non-Destructive Testing Techniques
- Ginseng Biological Effects and Applications
- Ferroelectric and Negative Capacitance Devices
Xiangya Hospital Central South University
2023-2025
Central South University
2001-2025
Chengdu University of Technology
2019-2024
Wenzhou University of Technology
2024
Wenzhou University
2024
Xiangtan University
2023-2024
Changsha University of Science and Technology
2021-2022
Harbin Engineering University
2021-2022
Northwest A&F University
2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2021
Abstract Macrophages are among the most abundant immune cells in colorectal cancer (CRC). Re-educating tumor-associated macrophages (TAMs) to switch from protumoral anti-tumoral activity is an attractive treatment strategy that warrants further investigation. However, little known about key pathway activated TAMs. In this study, infitrating CD206 + TAMs CRC were sorted and subjected RNA-seq analysis. Differentially expressed genes found be enriched unfolded protein response/endoplasmic...
In this study, we replaced fish meal with peanut (PM) in isonitrogenous and isolipidic diets for Pacific white shrimp at inclusion levels of 0, 70, 140, 210, 280 350 g kg−1. The were hand-fed to three independent groups times a day over 6-week period. Shrimp fed PM level kg−1 or higher had lower per cent weight gain compared those the basal diet, whereas 140 feed utilization protein efficiency ratio diet. feeding rate survival protease activity 210 than that Diets containing caused an...
// Weina Zhang 1 , Lechuang Chen Kai Ma Yahui Zhao Xianghe Liu Yu Wang Mei Shufang Liang 2 Hongxia Zhu Ningzhi Xu 1, Laboratory of Cell and Molecular Biology & State Key Oncology, Cancer Hospital, Chinese Academy Medical Sciences Peking Union College, Beijing 100021, P.R. China Biotherapy Center, West Sichuan University, Collaborative Innovation Center for Biotherapy, Chengdu 610041, Correspondence to: Zhu, email: drhxzhu@cicams.ac.cn Xu, xuningzhi@cicams.ac.cn Keywords: TAM, colon...
ABSTRACT Aims The gradient captures the continuous transitions in connectivity, representing an intrinsic hierarchical architecture of brain. Previous works hinted at dynamics but did not verify them. Cognitive impairment is a common comorbidity temporal lobe epilepsy (TLE). Gradient techniques provide framework that could promote understanding neural correlations cognitive decline. Methods Thirty patients with TLE and hippocampal sclerosis 29 matched healthy controls (HC) were investigated...
This study aimed to comprehensively explore the cerebellar structural and functional changes in temporal lobe epilepsy (TLE) its association with clinical information.
In this study, we conducted a thorough investigation of the transport characteristics thermoelectric devices, p–n junction diodes, and p–i–n homojunction phototransistors based on monolayer (ML) GeSe.
Krüppel-like factor 4 (KLF4) is a transcription and functions as tumor suppressor or promoter in different cancer types. KLF4 regulates many gene expression, thus affects the process of cell proliferation, differentiation, apoptosis. Recently, was reported to induce senescence during generation induced pluripotent stem (iPS) cells, but exact mechanism still unclear. In this study, we constructed two doxycycline-inducing models, demonstrated overexpression could promote senescence, detected...
A method of monitoring the transmission line galloping based on fiber Bragg grating (FBG) fitting sensor is proposed and verified by video in overhead experiment. The can be used to measure tension, mode amplitude horizontal vertical directions real-time, simultaneously. functions this were confirmed 92 hours results influence wind speed direction measurement also analyzed. Compared with method, it has advantage being able tension line, higher resolution real-time regardless weather...
Paclitaxel exerts its cytotoxic effect by kinetic suppression of microtubules that block cells in the G2/M phase cell cycle and trigger apoptosis. To investigate apoptosis induced paclitaxel nasopharyngeal carcinoma (NPC), possible molecular mechanism action, human NPC lines HNE-1 (bearing wild-type p53) CNE-2 mutant were treated with different concentrations paclitaxel. Apoptosis was determined staining propidium iodide also DNA fragmentation. Protein expression levels p53, bcl-2 bcl-xl...
To facilitate better implementation of flood control and risk mitigation strategies, a model for evaluating the defense capability China is proposed in this study. First, nine indicators such as slope precipitation intensity are extracted from four aspects: objective inclusiveness, subjective prevention, etc. Secondly, entropy weight method multi-attribute decision making (MADM) improved three-dimensional technique order preference by similarity to ideal solution (3D-TOPSIS) were combined...
Abstract Due to the increasing incidence and mortality, early diagnosis, specific targeted therapies, prognosis for colorectal cancer (CRC) attract more attention. Wild‐type p53‐induced phosphatase 1 (Wip1) karyopherin α2 (KPNA2) have been regarded as oncogenes in many cancers, including CRC. Wip1 dephosphorylates p53 inactivate it. TP53 activator inhibitor downregulate KPNA2 expression. Therefore, we speculate that may co‐operate with modulate CRC progression a p53‐dependent manner. Here,...
Strategies to increase radiosensitivity are urgently needed. Combining radiosensitizing reagents with radiotherapy could improve the outcome of cancer treatment. Some preclinical studies showed that sepantronium bromide (YM155) sensitize cells radiation by inhibiting survivin protein. In this study, we try investigate function YM155 on esophageal squamous cell carcinoma (ESCC) cells.ESCC lines were treated and YM155, efficacy was evaluated counting kit-8 assay clonogenic survival assay. Cell...
Abstract A 60‐d feeding trial was conducted to investigate the effect of dietary maize starch on growth performance, feed utilization, and apparent digestibility coefficient ( ADC ) key hepatic enzyme activities regulating glycolytic gluconeogenic metabolic pathways juvenile obscure puffer, Takifugu obscurus (Abe) (initial body weight = 7.9 ± 0.2 g). Five isonitrogenous isolipidic diets containing graded levels (10, 15, 20, 25, 30%) were formulated. Results demonstrated that gain WG ),...
Aiming at high performance requirements of snake-like robots under complex environment, we present a control system our proposed design which utilizes STM32 as the core processor and incorporates real-time image acquisition, multisensor fusion, wireless communication technology. We use Solidworks to optimize head, body, tail joint structure robot. The is with simple-circuit multidegrees freedom are attributed flawless mechanical structure. propose method based on simplified CPG model....
In this article, we explore the ballistic transport limits of p- and n-type monolayer (ML) WSi2N4 metal-oxide-semiconductor field-effect transistors (MOSFETs) at sub-5 nm scale. The results show that varying doping concentration, gate length, underlap region (LUL) structure can effectively tune on-state current (Ion) subthreshold swing (SS) MOSFETs. Notably, Ion, delay time (τ), power dissipation (PDP) optimized p-type MOSFETs still fulfill high-performance standard International Technology...
Targeting EGFR combined with chemotherapy is one of the most valuable therapeutic strategies in colorectal cancer. However, resistance remains a major obstacle to improve efficacy. IRE1α-XBP1s signaling pathway activated many malignant tumors, and plays important roles chemoresistance. Therefore, might be potential target overcome chemoresistance In this study, we detected activation patient cancer tissues cell lines. The phosphorylation level IRE1α spliced XBP1s were aberrantly elevated...
Background Cerebellar functional alterations are common in patients with mesial temporal lobe epilepsy (MTLE), which contribute to cognitive decline. This study aimed deepen our knowledge of cerebellar MTLE. Methods In this study, participants were recruited from an ongoing prospective cohort 13 left TLE (LTLE), 17 right (RTLE), and 30 healthy controls (HCs). Functional magnetic resonance imaging data collected during a Chinese verbal fluency task. Group independent component (IC) analysis...