A5103034385- Nanoplatforms for cancer theranostics
- Analog and Mixed-Signal Circuit Design
- Photonic and Optical Devices
- Parasites and Host Interactions
- Luminescence Properties of Advanced Materials
- Semiconductor Lasers and Optical Devices
- Mosquito-borne diseases and control
- Photodynamic Therapy Research Studies
- Radio Frequency Integrated Circuit Design
- Advancements in PLL and VCO Technologies
- Advancements in Semiconductor Devices and Circuit Design
- Viral Infections and Immunology Research
- Parasite Biology and Host Interactions
- Advanced biosensing and bioanalysis techniques
- Photoacoustic and Ultrasonic Imaging
- Advanced Nanomaterials in Catalysis
- Advanced MEMS and NEMS Technologies
- Cytomegalovirus and herpesvirus research
- Zoonotic diseases and public health
- Digital Filter Design and Implementation
- Advanced Sensor and Energy Harvesting Materials
- Smart Grid and Power Systems
- Neuroscience and Neural Engineering
- Nanowire Synthesis and Applications
- Advanced Chemical Sensor Technologies
Shenzhen Center for Disease Control and Prevention
2009-2024
China Railway Group (China)
2024
China Railway 18th Bureau Group Corporation
2024
Guangxi Communication Design Group Co., LTD (China)
2023
Tongji University
2023
Xidian University
2013-2023
National Institute for Parasitic Diseases
2023
China Design Group (China)
2023
Huazhong University of Science and Technology
2019-2021
Wuhan National Laboratory for Optoelectronics
2019-2021
In this research, a new type of mitochondrial-imaging probe using spindle nanocomposite with adjustable aspect ratios and enhanced upconversion luminescent (UCL) property was designed for synergistic immune–photodynamic anticancer theranostics. Gold nanoparticles are coated on the surface spindle-like layer-by-layer (LBL), which makes have better red UCL enhancement under NIR excitation, plasmon resonance (SPR) peak can be exactly predicted by discrete dipole scattering calculation. The...
Sensitive identification and effective inactivation of the virus are paramount for early diagnosis treatment viral infections to prevent risk secondary transmission viruses in environment. Herein, we developed a novel two-step fluorescence immunoassay using antibody/streptavidin dual-labeled polystyrene nanobeads biotin-labeled G-quadruplex/hemin DNAzymes with peroxidase-mimicking activity sensitive quantitation efficient living Zika (ZIKV). The can specifically bind ZIKV through E protein...
This paper describes a component-level mapping between linear- and log-domain filters. A modified multiple input class AB log-integrator with both f- Q-tuning is presented. 3/sup rd/-order elliptic filter derived from LC ladder prototype designed using the proposed log building blocks including implementation of transmission zero. Simulated frequency responses, THD SNR, obtained large signal transient analysis, are given. The for 2 V supply consumes 1.3 mW cutoff 10 MHz. It can easily be...
In this research, a degradable uniform mesoporous platform was designed as an imaging-guided photothermal therapy (PTT)/photodynamic (PDT) agent. Fe3O4 nanoparticles were prepared using the solvothermal method, and layer of SiO2 coated onto them sol-gel etching processes, then these ultra-small up-conversion (UCNPs) loaded into porous structure through electrostatic conjunction physical absorption. By adjusting Fe3O4@mSiO2 mSiO2 with high surface area carrier host could be obtained...
Development of sensitive, convenient, and cost-effective virus detection product is great significance to meet the growing demand clinical diagnosis at early stage infection. Herein, a naked-eye readout immunoassay by means virion bridged catalase-mediated in situ reduction gold ions growth nanoparticles, has been successfully proposed for rapid visual Enterovirus 71 (EV71). Through tailoring morphologies produced nanoparticles (GNPs) varying between dispersion aggregation, distinguishing...
Photoactive theranostics including photodynamic therapy (PDT) hace aroused an intensive interest that combines medical diagnostics with treatment under a single irradiation laser. However, the conventional organic PDT agents usually suffer from aggregation caused by quenching effect. In this research, we designed core–shell–shell (CSS) UCNPs NaGdF4 as host, and could emit higher blue/green light energy transfer processes among Nd/Yb/Tm/Gd/Tb 808 nm When CSS were combined MnO2 semiconductor...
In this research, four heuristic algorithms (HAs), including simulated annealing (SA), improved with a harmony search algorithm (HSA), particle swarm optimization (PSO), and genetic (GA), were used to optimize the luminescent intensity of phosphor. Among HAs, HSA got better phosphors than SA (without using known coded concentration). The PSO gradually results increased generation, GA could find best local shorter time. After further analysis 340 phosphors, we found that final brightness has...
In this research, typical organic/inorganic photothermal therapy (PTT) agents were designed with a combination of upconversion luminescent (UCL) or near-infrared (NIR) II imaging rare-earth nanomaterials for photo-acoustic (PA)/UCL/NIR imaging-guided PTT under NIR laser irradiation. The results show the following: (1) effect mainly comes from absorption and partly UCL light conversion. (2) Visible emission is quenched by coated agent visible absorption, indicating that excitation may play...
Clonorchis sinensis is an important foodborne zoonosis worldwide and prevalent in China for more than 2000 years. According to the experience of controlling Schistosoma japonica, started establish integrated control strategy C. endemic areas. Lou village, largest village Shenzhen city South was taken as a pilot site. This longitudinal study assessed infection status among people intermediate hosts from 2006 2014 village. After continuous intervention with strategy, prevalence decreased...
A lanthanide-chlorophyll nanocomposite with enhanced red emission under a near-infrared laser was designed for dual-modal imaging-guided surgery navigation and anti-cancer theranostics.
Photodynamic therapy (PDT) is a promising and effective method for tumor that relies on the reactive oxygen species (ROS) produced by photosensitizers at specific wavelengths to inhibit cells.
In this research, upconversion nanoparticles (UCNPs) are used as a light conversion carrier, and their deep source penetrability is closely combined with ultrathin two-dimensional (2D) Ti3C2Tx to explore the application efficiency of complex in phototherapy. Due advantages 2D its high absorbance ultraviolet/visible light, rich atomic defects load drugs, adjustable thinner structure, material beneficially applied energy donor. UCNPs@Ti3C2Tx photothermal 20.7% proven ability generate reactive...
A novel output stage for OTAs and opamps gain enhancement is described. The proposed circuit using positive feedback to cancel the conductance allows DC be enhanced without affecting bandwidth of OTA opamp.
SUMMARY A suspected dengue fever outbreak occurred in 2010 at a solitary construction site Shenzhen city, China. To investigate this epidemic, we used serological, molecular biological, and bioinformatics techniques. Of nine serum samples from patients, detected seven positive for virus (DENV) antibodies, eight DENV-1 RNA, three containing live viruses. The isolated virus, SZ1029 strain, was sequenced confirmed as DENV-1, showing the highest E-gene homology to D1/Malaysia/36000/05...
Fibre optics sensors have been identified as very good candidates for environmental monitoring inside the silicon detectors operated at CERN's Large Hadron Collider. In this study, we present results from first highly sensitive relative humidity distributed sensor with kilometres sensing range. The setup is a 70 cm spatial resolution phase-sensitive Optical Time Domain Reflectometry (OTDR) and able to monitor fibre lengths up 10 km. coating effect also evaluated, analysing different...
This report analyzes the national surveillance data for schistosomiasis in 2021 to understand current status and provide evidence further policy actions promote elimination. analysis is line with National Surveillance Plan of Schistosomiasis, which was revised 2020 adapt new stage moving towards elimination.Data from humans, livestock, snails were collected 13 provincial-level administrative divisions (PLADs) analyzed using descriptive epidemiological methodology. The antibody-positive rate...
This paper describes a high performance CMOS transconductor with linearity-improved V-I conversion stage, novel output stage which allows us to boost the resistance without bandwidth penalty and symmetric CMFB system enhance loop gain improve CMFB's linearity. A 3 MHz fifth-order elliptic low-pass filter is designed using proposed transconductor.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
An 8-channel serial link transceiver realizes 20 Gb/s full duplex total I/O throughput with <700 mW dissipation from a 1.5 V supply and occupies 2 mm/sup 2/ in 0.16 /spl mu/m CMOS. analog DLL allows tracking of frequency offset up to 400 ppm. The receiver, employing an integrate-and-dump front-end, achieves 30 mVpp sensitivity.
This paper presents the design of a 7th-order continuous-time Bessel filter using new low-voltage and highly-linear BiCMOS OTA. A high-gain parasitic-insensitive integrator is obtained by an active capacitor scheme. The has been fabricated in 1 /spl mu/m, double-poly 6-GHz process. operated at 2.5 V supply nominal -3 dB cut-off frequency set 600 kHz. inband group delay variation less than 10 ns. THD measured with 100 kHz input signal -49 for 2 V/sub pp/ amplitude. can be tuned external...
An efficient distortion-correcting algorithm for the intra-coding of a depth map is presented by considering property flat area in map. The influence distortion reference pixels on rate-distortion (RD) cost function macro-block (MB) region analysed. Then, RD performance improved correcting first MB basis this analysis. Experiments show that synthesis view proposed method can achieve average peak signal-to-noise ratio (PSNR) 0.32 and 0.30 dB compared with JMVC8.5 plane segmentation-based...