A5101585499- Glioma Diagnosis and Treatment
- Endometrial and Cervical Cancer Treatments
- Brain Metastases and Treatment
- Pituitary Gland Disorders and Treatments
- Management of metastatic bone disease
- Colorectal and Anal Carcinomas
- Cervical Cancer and HPV Research
- Adrenal and Paraganglionic Tumors
- Growth Hormone and Insulin-like Growth Factors
- Testicular diseases and treatments
- Lung Cancer Research Studies
- Sarcoma Diagnosis and Treatment
- Heavy Metal Exposure and Toxicity
- Meningioma and schwannoma management
- Ferroptosis and cancer prognosis
- Nail Diseases and Treatments
- Arsenic contamination and mitigation
- Ovarian cancer diagnosis and treatment
- Fungal Infections and Studies
- Essential Oils and Antimicrobial Activity
- Cancer-related molecular mechanisms research
- Bladder and Urothelial Cancer Treatments
- Pharmacological Effects of Natural Compounds
- Trace Elements in Health
- Advanced Glycation End Products research
Guangzhou University of Chinese Medicine
2022-2025
Beijing YouAn Hospital
2024
Peking Union Medical College Hospital
2015-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2024
Capital Medical University
2024
Chinese Anti-Cancer Association
2024
First Hospital of Jilin University
2012-2024
Jilin University
2012-2024
Lanzhou University
2023-2024
First Hospital of Lanzhou University
2023
Concurrent chemoradiotherapy (CCRT) is the standard treatment for local advanced cervical cancer. However, elderly patients, studies are limited and outcomes controversial. We retrospectively analyzed efficacy tolerance of radical radiotherapy (RT) or CCRT in cancer patients performed comparisons between them. (≥70 years old) treated with RT January 2006 December 2014. For external beam radiotherapy, 50Gy 25 fractions 50.4Gy 28 were delivered via 3-dimensional conformal radiation therapy...
We aimed to analyze the outcomes of hypofractionated high-energy electron beam radiotherapy for treatment keloids. From February 1998 January 2012, 568 patients with a total 834 keloids underwent radiotherapy: 826 lesions postoperative radiotherapy, and 36 skin-grafting. Lesion size was >5 cm in 335 An electron-beam 6 or 7 MeV used, dose 18 Gy (two fractions 1-week interval) covering lesion 1-cm margin. The time between surgery 24-48 h. Skin-grafted 10-15 days after operation. median...
Arsenic poisoning is a public health problem worldwide. A few studies have reported the effects of arsenic exposure on adult cognitive function, but with limitations in subject selection and markers. Moreover, information regarding association between biomarker impairment scarce.We examined associations using Mini-Mental State Examination (MMSE) serum levels brain-derived neurotrophic factor (BDNF), potential status.We designed cross-sectional study that recruited 693 (18-60 years old)...
Objective: To assess the disparities in effectiveness and identify outcome predictors treatment of a targeted-first radiotherapy-first regimen with driver gene-positive lung cancer brain metastases.Materials Methods: This retrospective study analyzed patients metastases who received first-targeted first-radiotherapy regimens, respectively, SIB-WBRT (whole tissue 40 Gy/20 fractions, tumor boosted to 56-60 fractions) local irradiation (prescription dose range 20-60 Gy/2-25 most commonly...
Summary Type 2 diabetes is a major risk factor of the development atherosclerosis in humans. However, studies examining mechanisms underlying diabetes‐accelerated have been limited by lack suitable humanoid animal models. Pigs cardiovascular system that very similar to humans and useful as model for human physiology pathophysiology. In this study, we established new miniature pig studying dyslipidaemia diabetes. Chinese Guizhou minipigs were fed normal control diet or high‐fat/high‐sucrose...
A large body of evidence has shown a link between arsenic exposure and diabetes, but the underlying mechanisms have not yet been clarified. We explored association reduction skeletal muscle mass as potential mechanism insulin resistance for developing arsenic-related hyperglycemia. total 581 subjects were recruited from arsenic-endemic non-endemic areas in Bangladesh their fasting blood glucose (FBG), serum insulin, creatinine levels determined. Subjects' assessed by concentrations water,...
The extract of the stems Eurya chinensis R. Br. yielded three new terpenes (1–3) including two diterpenes and one triterpene, named euryachins C–E, as well known (4–6). structures these novel compounds were elucidated via spectroscopic analysis, especially IR, NMR spectroscopy HRESIMS data. Besides, all isolated evaluated for antibacterial activity against Escherichia coli, Bacillus cereus, Staphylococcus aureus Methicillin-resistant S. (MRSA). Additionally, inhibitive COVID-19 was studied...
The aim of this study was to investigate patterns and locations lymph node metastasis in locally advanced cervical cancers. A total 244 consecutive patients with stage IIb cancer were retrospectively evaluated. Contrast-enhanced CT scans used for grading. Lymph nodes the shortest axis (>1 cm) categorized as positive those between 0.5 1 cm suspicious. All (LNs) also classified by their anatomic locations. Nine hundred thirty-one LNs (136 795 suspicious) identified. Sixty-three (25.8%) had...
Hyperglycemia-induced renal fibrosis causes end-stage disease. Clopidogrel, a platelet inhibitor, is often administered to decrease cardiovascular events in diabetic patients. We investigated whether clopidogrel can reduce diabetes-induced streptozotocin-induced type 1 diabetes murine model and fibronectin involvement this protective response. Diabetic age-matched controls were sacrificed three months after the onset of diabetes, additional animals further treated with or vehicle for months....
Pathological examination combined with tumor markers has become a standard for the diagnosis of intracranial germ cell tumors (ICGCTs), but current concept 'secreting tumors' and three empirically highly specific diagnostic criteria (β-hCG ≥ 50 IU/L or αFP 10 ng/mL; β-hCG 100 > 25 ng/mL) are not based upon pathology CSF cytology. Further investigation is needed to re-evaluate their value.A multidisciplinary team was created. Valid β-hCG/αFP data were collected from cases ICGCTs confirmed by...
To summarize the etiologies of pituitary stalk thickening (PST) and natural course indistinguishable PST. Clinical information, including symptoms at onset laboratory, imaging, operative, pathological, follow-up data, patients with MRI-confirmed PST Peking Union Medical College Hospital from January 2014 to May 2017 was collected reviewed. Of 321 eligible PST, 28.3% were ≤18 years old. Central diabetes insipidus initial symptom in 68.8% patients. At least one anterior hormone deficit found...
CD44 is reported to be involved in tumor invasion and metastasis. However, the role of cancer stem cell marker bladder still remains controversial. Hence, correlations between expression clinicopathological features prognosis were investigated. Publications using immunohistochemical methods identified. The Cancer Genome Atlas (TCGA) data also analyzed. odds ratios (ORs) or hazard (HRs) with their 95% confidence intervals (95% CIs) calculated. 14 studies involving 1107 tissue samples...
The synthetic compound NO-1886 (ibrolipim) is a lipoprotein lipase activator that has been proven to be highly effective in lowering plasma triglycerides. Recently, we found also reduced free fatty acids and glucose high-fat/high-sucrose diet-induced diabetic rabbits. In the current study, investigated effects of treatment on ectopic lipid deposition islet pathology miniature swine fed diet. Our results showed feeding this diet caused insulin resistance, increased non-adipose tissue, such as...
Considering internal organ motion and tumor regression, it is controversial to use intensity-modulated radiation therapy (IMRT) in definitive radiotherapy for cervical cancer. In this study, we evaluated the efficacy toxicity of IMRT combined with dose-escalated intracavitary brachytherapy (ICBT) total, 373 consecutive FIGO-stage-IIB cancer patients treated ICBT concurrent chemotherapy were included study. A dose 50.4 Gy 28 fractions was delivered pelvis IMRT. Weekly cone-beam computed...