A5007465482- Advanced Radiotherapy Techniques
- Endometrial and Cervical Cancer Treatments
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Lung Cancer Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Head and Neck Cancer Studies
- Radiomics and Machine Learning in Medical Imaging
- Management of metastatic bone disease
- Hepatocellular Carcinoma Treatment and Prognosis
- Advances in Oncology and Radiotherapy
- Medical Imaging Techniques and Applications
- Ovarian cancer diagnosis and treatment
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Cervical Cancer and HPV Research
- Bladder and Urothelial Cancer Treatments
- Esophageal and GI Pathology
- Nonmelanoma Skin Cancer Studies
- Radiation Dose and Imaging
- Renal cell carcinoma treatment
- Pancreatic and Hepatic Oncology Research
- Brain Metastases and Treatment
- Lung Cancer Treatments and Mutations
- Diversity and Career in Medicine
University of California, Los Angeles
2018-2025
University of Colorado Cancer Center
2023-2025
UCLA Jonsson Comprehensive Cancer Center
2023-2025
University of Colorado Denver
2023-2025
University of Virginia Medical Center
2024
Merck Institute for Science Education
2024
UCLA Health
2018-2023
Radiation Oncology Associates
2019-2023
Moffitt Cancer Center
2014-2018
National Center of Radiobiology and Radiation Protection
2018
Basal cell carcinoma (BCC) is the most common form of skin cancer in United States. Due to high frequency, BCC occurrences are not typically recorded, and annual rates incidence can only be estimated. Current estimated 2 million Americans affected annually, this continues rise. Exposure radiation, from either sunlight or previous medical therapy, a key player development. as aggressive other cancers because it less likely metastasize. However, surgery radiation prevalent treatment options,...
The NCCN Guidelines for Merkel Cell Carcinoma (MCC) provide recommendations diagnostic workup, clinical stage, and treatment options patients. panel meets annually to discuss updates the guidelines based on comments from expert review members, institutional review, as well submissions within external organizations. These Insights focus introduction of a new page locally advanced disease in setting node negative status, entitled “Clinical N0 Disease, Locally Advanced MCC.” This algorithm...
Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous soft tissue sarcoma and affects an estimated 1,500 people annually in the United States. DFSP frequently exhibits extensive local infiltration. Initial treatment through surgical excision, care should be taken to ensure that negative margins are achieved minimize recurrence. Although has reported high rate of recurrence, metastasis more uncommon. Fibrosarcomatous aggressive variant with increased risk for recurrence metastasis. If...
Importance The KEYNOTE-A18 trial demonstrated that adding concurrent and adjuvant pembrolizumab to chemoradiotherapy brachytherapy significantly improved survival in patients with newly diagnosed, locally advanced cervical cancer. However, considering the annual global incidence of 660 000 cases cancer, including 13 820 US 2024, incorporating this regimen into standard care could have substantial health economic implications for both system. Objective To determine cost-effectiveness...
Sarcopenia is an independent predictor of clinical outcomes in multiple gastrointestinal cancers. Total psoas area (TPA), as measured on a single cross-sectional CT image at the L4 vertebral body level, has been correlated with sarcopenia. We sought to evaluate whether TPA was predictive acute grade ≥3 toxicity, pathologic response, and overall survival patients locally advanced esophageal cancer receiving tri-modality therapy.An institutional database treated neoadjuvant chemoradiation...
Cervical cancer (CC) disproportionately affects minorities who have higher incidence and mortality rates. Standard of care for locally advanced CC involves a multimodality approach including brachytherapy (BT), which independently improves oncologic outcomes. Here, we examine the impact insurance status race on BT utilization with SEER database.In total, 7,266 patients stage I-IV diagnosed from 2007 to 2015 were included. utilization, overall survival (OS), disease-specific (DSS)...
Abstract Background Studies suggest treatment outcomes may vary between high ( HVC )‐ and low‐volume centers LVC ). Radiation therapy RT ) for head neck cancer HNC requires weeks of treatment, the inconvenience which influence a patient's choice location. We hypothesized that receipt at would compared to patients evaluated , but who chose receive . Methods From 1998 2011, 1930 were then treated with either or Time‐to‐event factors compared. Results Median follow‐up was 34 months. delivered...
We compared pathologic complete response (pCR) rate, toxicity, and postoperative complications between patients treated preoperatively with 50.4 Gy versus dose escalation dose-painting intensity-modulated radiation therapy (dp-IMRT) to 56 in locally advanced esophageal cancer. evaluated cancer 2006 2014 preoperative IMRT chemoradiation a of Gy. The endpoints were pCR toxicity. identified 113 (50.4 Gy: n = 40; 73). There no significant differences tumor or patient characteristics. Patients...
Cervical cancer is the third most common malignancy among female patients worldwide. Signal transducer and activator of transcription 3 (STAT3) a factor which regulates variety cellular physiological activities including cervical cancer. Sanguinarine (SNG) natural plant-derived benzophenanthridine alkaloid that possesses antitumor in several cells. However, its anticancer effect on human cells underlying mechanisms have not been fully defined.In this study, inhibitory SNG proliferation...
Background Despite neoadjuvant chemoradiation (nCRT) followed by esophagectomy for locally advanced esophageal cancer, locoregional recurrence (LRR) is common and factors associated with LRR have not been clearly identified. Methods Patients were identified from a single institution, prospectively maintained database (1996‐2013). Patterns of described analyzed using competing risks regression models. Results Of the 456 patients treated nCRT surgery, 167 developed recurrence. Locoregional...
AIMTo evaluate the value of pre-treatment 18F-FDG PET/CT in patients with HCC following liver radioembolization. METHODSWe identified 34 who underwent an FDG scan prior to hepatic radioembolization at our institution between 2009 and 2013.Patients were
Centrally located lung tumors present treatment challenges given their proximity to mediastinal structures including the central airway, esophagus, major vessels, and heart. Therapeutic options can be limited for medically inoperable patients, particularly if they have received previous thoracic radiotherapy. High dose rate (HDR) brachyablation was developed improve therapeutic ratio patients with tumors. The purpose of this study is report initial safety efficacy outcomes malignancies.From...
Purpose Data on prostate cancer (PCa) treatment in Africa remains under-reported. We present a review of the management PCa at center largest tertiary referral facility Ghana, with emphasis curative treatment. Methods retrospectively reviewed data 1,074 patients seen National Center for Radiotherapy and Nuclear Medicine from 2003 to 2016. Patient disease characteristics presentation are presented using descriptive statistics. The χ2 Fisher's exact tests Mann-Whitney U test were used analyze...
The incidence of esophageal cancer (EC) is increasing in the USA. Neoadjuvant therapy for locally advanced cancers followed by surgical resection standard care. most common post-esophagectomy cardiac complication atrial fibrillation (AF). New-onset postoperative AF can require a prolonged hospital stay and may confer an overall poorer prognosis. In this study, we seek to identify clinical factors associated with AF.Query IRB approved database 1,039 esophagectomies at our institution revealed...
Abstract Background and aims The role of three-dimensional positron emission tomography/computed tomography (3 D PET/CT) in esophageal tumors that move with respiration have potential for significant mucosal inflammation is unclear. aim this study was to determine the correlation between gross tumor volumes derived from 3 PET/CT endoscopically placed fiducial markers. Methods This a retrospective, IRB approved analysis 40 patients cancer fiducials implanted PET/CT. centroid each identified...
The appropriate adjuvant treatment for resected pancreatic cancer remains a controversy. We sought to determine the effect of on overall survival (OS) in patients with tail adenocarcinoma.Retrospective review upfront surgically treated at our institution between 2000-2012 was performed outcomes and without radiation therapy (RT). Survival curves were calculated according Kaplan-Meier method. Univariate analysis (UVA) multivariate (MVA) using Cox proportional hazards model.Thirty-four met...