Shanker Gupta

ORCID: 0000-0003-4664-3469
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About
Contact & Profiles
Research Areas
  • Electrostatics and Colloid Interactions
  • Neonatal Respiratory Health Research
  • Surfactants and Colloidal Systems
  • Lipid Membrane Structure and Behavior
  • Chemical and Physical Properties in Aqueous Solutions
  • Biosimilars and Bioanalytical Methods
  • Crystallization and Solubility Studies
  • Fatty Acid Research and Health
  • Biomedical Ethics and Regulation
  • Pharmaceutical studies and practices
  • Science, Research, and Medicine
  • Biotin and Related Studies
  • Neuroscience of respiration and sleep
  • Genomics, phytochemicals, and oxidative stress
  • Surgical Sutures and Adhesives
  • Protein purification and stability
  • Electrowetting and Microfluidic Technologies
  • Cancer Genomics and Diagnostics
  • Hepatitis Viruses Studies and Epidemiology
  • Consumer Attitudes and Food Labeling
  • NF-κB Signaling Pathways
  • Mosquito-borne diseases and control
  • Dermatologic Treatments and Research
  • Retinoids in leukemia and cellular processes
  • Global Health and Surgery

National Cancer Institute
2007-2024

Mayo Clinic in Florida
2007

Southern Research Institute
2007

National Institutes of Health
2001

Abbott Fund
1994-1996

Abbott (United States)
1990-1994

We have synthesized pulmonary surfactant apoprotein SP-B peptides by solid-phase chemistry and demonstrated their ability to enhance the surface-active properties of synthetic lipid mixtures. The were reactive with antiserum generated against native bovine peptide. Both conferred surfactant-like mixtures as assessed a Wilhelmy balance pulsating bubble surfactometer. Likewise, restored compliance isolated surfactant-deficient rat lungs. This work demonstrates utility functional component for...

10.1073/pnas.87.7.2633 article EN Proceedings of the National Academy of Sciences 1990-04-01

Abstract The concept of green chemoprevention was introduced in 2012 by Drs. Jed Fahey and Thomas Kensler as whole-plant foods and/or extract-based interventions demonstrating cancer prevention activity. Refining concepts research proof-of-principle approaches are highlighted within this review. Early included extensively investigated whole foods, including broccoli sprouts black raspberries showing dose–responsive effects across a range activities both animals humans with minimal or no...

10.1158/1940-6207.capr-23-0308 article EN cc-by-nc-nd Cancer Prevention Research 2024-01-19

The compatibility and biological activity of aldesleukin (a form recombinant interleukin-2) in the presence selected i.v. drugs during simulated Y-site administration was studied. Five milliliters 33,800 IU/mL 5% dextrose injection mixed glass test tubes with 5 mL each 19 prepared at concentrations used routine clinical practice. combinations assessed by visual examination spectrophotometry 0, 0.5, 1, 2 hours after preparation, bioassays were conducted to determine combinations. Lorazepam...

10.1093/ajhp/52.21.2423 article EN American Journal of Health-System Pharmacy 1995-11-01

Abstract The NCI’s PREVENT Cancer Preclinical Drug Development Program is a peer-reviewed program designed to support the preclinical development of promising agents and biomarkers for cancer interception/prevention towards clinical applications. not grant but allocates NCI contract resources advance approved projects in milestone-driven manner. Results obtained through are returned applicant PIs used further by applicants or partnership with NCI. Resources available include efficacy...

10.1158/1940-6215.tacpad22-ia007 article EN Cancer Prevention Research 2022-12-01
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