A5101814185- RNA modifications and cancer
- MicroRNA in disease regulation
- Cancer-related Molecular Pathways
- Occupational and environmental lung diseases
- TGF-β signaling in diseases
- Cardiac tumors and thrombi
- Cancer-related molecular mechanisms research
- Cardiac Structural Anomalies and Repair
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Caveolin-1 and cellular processes
- Spinal Fractures and Fixation Techniques
- Medical Imaging and Pathology Studies
- RNA Research and Splicing
- Scoliosis diagnosis and treatment
- Medical Imaging and Analysis
- Hepatitis Viruses Studies and Epidemiology
- Trace Elements in Health
- Pericarditis and Cardiac Tamponade
- Pancreatic and Hepatic Oncology Research
- Angiogenesis and VEGF in Cancer
- Acute Kidney Injury Research
- Vascular Tumors and Angiosarcomas
- Advanced X-ray Imaging Techniques
- Phytoestrogen effects and research
- Proteoglycans and glycosaminoglycans research
China Medical University
2012-2024
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
2021
Shandong Agricultural University
2020
First Affiliated Hospital of Xi'an Jiaotong University
2020
Liaoning Cancer Hospital & Institute
2020
Heilongjiang Bayi Agricultural University
2019
Xiamen University
2018
Army Medical University
2013
Southwest Hospital
2008-2013
First Hospital of China Medical University
2012
In Brief Study Design. Retrospective review of anterior and posterior fusions for treatment Lenke5C adolescent idiopathic scoliosis (AIS). Objective. To compare the clinical radiographic results versus pedicle screw instrumentation in AIS. Summary Background Data. Anterior instrumentations are 2 established methods correcting However, there few reports that methods. Methods. Forty-six consecutive patients with AIS curves underwent selective lumbar or thoracolumbar fusion (1999-2005)....
MicroRNA-663a expression is downregulated in several tumors. However, its functions and mechanisms human non-small cell lung (NSCLC) cancer remain obscure. The present study aimed to identify the pattern, biological roles potential by which miR-663a dysregulation associated with NSCLC. We examined level of 62 cases NSCLC tissues 5 lines reverse transcription PCR. In vitro, gain-of-function loss-of-function experiments were performed examine impact on proliferation, cycle progression invasion...
Abstract Background The biologically active form of transforming growth factor-β1 (TGF-β1) plays a key role in the development lung fibrosis. CD36 is involved transformation latent TGF-β1 (L-TGF-β1) to TGF-β1. To clarify silica-induced fibrosis, rat silicosis model was used observe both inhibition L-TGF-β1 activation and antifibrotic effect obtained by lentiviral vector silencing expression. Methods induced intratracheal injection 10 mg silica per expression silenced administration...
HPV 16 E6 upregulates hTERT expression in lung cancer cells. However, the underlying molecular mechanism is unclear. In this paper, E6, LKB1, SP1, and mRNA levels were detected brushing cells of patients with (n = 106) benign disease 68) by qRT-PCR. The significantly increased malignant group compared (P < 0.01). Conversely, level LKB1 was decreased Furthermore, correlation between Sp1, hTERT, performed, our results indicated that positive, but negative To investigate potential relationship...
Abstract Objectives To assess the qualitative and quantitative characteristics of suspected cardiac masses by contrast‐enhanced ultrasonography (CEUS) to evaluate its usefulness. Methods Twenty‐eight adult patients with were selected for this study. All them examined conventional transthoracic echocardiography (TTE) CEUS. The location, attachment point, basement, morphology, size, boundary, internal echo, shape change, range motion, length, area, effect on hemodynamics, peak enhancement...
Silicosis is a kind of pneumoconiosis caused by inhalation silica dust, which characterized lung fibrosis. The biologically active form transforming growth factor-β1 (TGF-β1) plays key role in the development CD36 involved transformation latent TGF-β1 (L-TGF-β1) to TGF-β1. antagonistic effect synthetic peptide was analyzed administration (93-110) silicosis model mice. hydroxyproline content + group significantly lower than that other experimental groups [silica and (208-225) groups] (p <...
Pneumonia is one of the commonest causes death worldwide. High‑temperature requirement A2 (HtrA2) a proapoptotic mitochondrial serine protease involved in caspase‑dependent or caspase‑independent cell apoptosis. UCF‑101 (5‑[5‑(2‑nitrophenyl) furfuryl iodine]‑1,3‑diphenyl‑2‑thiobarbituric acid), an inhibitor HtrA2, has protective effect on organs various diseases by inhibiting The aim present study was to explore whether lungs pneumonia. A lipopolysaccharide (LPS)‑induced pneumonia model...
Objectives In animal models with constrictive pericarditis (CP), detecting the function of cardiac systole by conventional noninvasive ultrasound is a challenge. We aimed to detect dysfunction in rat CP early stage layered speckle tracking. Methods compared model (n = 23, injected solution 1‐mg/mL lipopolysaccharides [0.5 mL] and 10% talc suspension mL]) control group 20, no injection). After 8 weeks, echocardiography tracking were used assess left ventricular structures functions groups....
Abstract Background Among primary cardiac tumors, atypical lipoma is very rare. In particular, cases with lipomas in both the pericardium and atria are even Case presentation We report case of a 49-year-old male patient presented to our department because chest pain. Echocardiography revealed two large masses right atrium. Then tumors were completely resected histopathological examination lipoma. The recovered well without any complication discharged from hospital. Conclusions rare huge...
Abstract Background Huntingtin‐interacting protein 1‐related (HIP1R) is a multi‐domain gene that exerts many cellular functions including altering T cell–mediated cytotoxicity and controlling intracellular trafficking. However, its clinical significance function in gastric cancer (GC) have not been described. Methods The expression levels of HIP1R were tested by the transcriptional translational analysis immunohistochemistry (IHC) matched adjacent non‐tumorous vs tumor tissue specimens....
Breast capillary hemangioma is a type of benign vascular tumor which rarely seen. Little known about its presentation on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Here, we describe case suspicious breast lesion detected by DCE-MRI and pathologically confirmed as hemangioma. Our indicates that small mass with superficial location, clear boundary, homogeneous enhancement the possible diagnosis hemangioma, whereby even presents washout curve.
Background Susceptibility-weighted imaging (SWI) has been proven to be superior T2*-weighted and also other existing magnetic resonance (MRI) techniques for the detection of iron content hemorrhage in brain. The purpose this study was compare SWI with T1WI, T2WI T2*WI detecting splenic siderotic lesions. Methodology/Principal Findings Twenty-two patients nodule were imaged non-contrast MRI T2WI, at 3.0 Tesla. Imaging data independently analyzed by two experienced radiologists. number nodules...
Bovine herpesvirus type 1 (BoHV-1), a member of the Alphaherpesvirinae, causes variety diseases, which result in significant economic losses worldwide. Envelope glycoprotein D (gD) BoHV-1 plays an important role viral entry into permissive cells, and protective immune response. The fine mapping epitope on gD will contribute to understanding pathogenesis development alternative vaccines against various diseases associated with BoHV-1. We previously reported preparation monoclonal antibody...