A5100687936- Nerve injury and regeneration
- Neurogenesis and neuroplasticity mechanisms
- Tryptophan and brain disorders
- Neuroendocrine regulation and behavior
- thermodynamics and calorimetric analyses
- Caveolin-1 and cellular processes
- Stress Responses and Cortisol
- Cancer-related Molecular Pathways
- Cancer-related molecular mechanisms research
- Neuroinflammation and Neurodegeneration Mechanisms
- Cholinesterase and Neurodegenerative Diseases
- Antimicrobial Peptides and Activities
- Silk-based biomaterials and applications
- Sperm and Testicular Function
- Nerve Injury and Rehabilitation
- Signaling Pathways in Disease
- Anesthesia and Neurotoxicity Research
- Intensive Care Unit Cognitive Disorders
- Hippo pathway signaling and YAP/TAZ
- RNA modifications and cancer
- Neuropeptides and Animal Physiology
- Cell death mechanisms and regulation
- Neurobiology and Insect Physiology Research
- Heat shock proteins research
- Neuroscience and Neuropharmacology Research
Beijing Anzhen Hospital
2022
Capital Medical University
2022
Nanjing Medical University
2006-2020
Jiangsu Province Hospital
2018-2020
Nanjing Drum Tower Hospital
2019
Ningbo University
2011-2017
First Hospital of Jilin University
2012
Jilin University
2012
Nanjing University
2004
We characterized cellular and molecular mechanisms involved in spermatogenesis following short-term heat exposure of murine testis. For these studies, we utilized a proteomic approach with two-dimensional gel electrophoresis (2DE) analyses mass spectroscopic identification proteins altered expression mouse testes at different times after shock. established proteome reference map from 7-wk-old testis linked to federated database. used tools analyze quantitative variations the tissue over time...
Background/Aims: Our previous study suggested the anti-tumor activity of sepia ink oligopeptide (SIO). Here we sought to investigate underlying molecular mechanism. Methods: Cell proliferation was evaluated by cell counting kit-8 (CCK-8) assay. apoptosis determined Annexin V/Propidium Iodide (PI) staining. The mitochondria pathway characterized quantification Bcl-2, Bax, Caspase-9 and Cyto-C. death receptor analyzed determinement Fas, Caspase-8 NIK. endoplasmic reticulum (ER)-dependent...
Abstract Background Cancer stem cells (CSCs) are regarded as the root of tumor progression, thus representing an anti-cancer therapy through targeting this cell sub-population. Methods Non-small lung cancer (NSCLC) CSCs were enriched by non-adherent spheroid formation analysis. Lentivirus infection was used to stably change gene expression. Cell cycle, EdU incorporation, apoptosis, viability, ALDH1 activity, and in vivo initiation assays performed detect effects Cryptotanshinone (CT), a...
Objective:This study aims to determine the diagnosis and prediction value of serum miR-184 miR-191 levels in patients with non-small-cell lung cancer (NSCLC).Methods:One hundred NSCLC were enrolled (NSCLC group) treated gefitinib. In addition, 59 pneumonia cases (pneumonia 51 healthy corresponding period (normal included. Serum expressions detected by real-time quantitative polymerase chain reaction. Furthermore, relationships between clinicopathological parameters analyzed. The use...
<h3>Objectives</h3> TRB-3 (tribbles 3), also called NIPK (neuronal cell death-inducible protein kinase) disrupts insulin signalling by binding to Akt and blocking their activation. TRB3 expression is highly regulated in many types, endoplasmic reticulum (ER) stress promotes cardiac cells. This work was examine function cultured myocytes mouse heart. <h3>Methods</h3> Cultured HL-1 murine atrial were treated with thapsigargin stimulated insulin. cells (2 µM), 24 h later (10 nM) or control...