A. Capelastegui

ORCID: 0000-0003-4689-2633
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About
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Research Areas
  • Pneumonia and Respiratory Infections
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Emergency and Acute Care Studies
  • Respiratory viral infections research
  • Respiratory and Cough-Related Research
  • Nosocomial Infections in ICU
  • Asthma and respiratory diseases
  • Advanced MRI Techniques and Applications
  • Respiratory Support and Mechanisms
  • Cardiac Imaging and Diagnostics
  • Liver Disease and Transplantation
  • Tracheal and airway disorders
  • Cancer Diagnosis and Treatment
  • Venous Thromboembolism Diagnosis and Management
  • Organ Transplantation Techniques and Outcomes
  • Sepsis Diagnosis and Treatment
  • Biological Research and Disease Studies
  • Aortic Thrombus and Embolism
  • Legionella and Acanthamoeba research
  • Abdominal vascular conditions and treatments
  • Occupational exposure and asthma
  • Nursing Diagnosis and Documentation
  • Gastroesophageal reflux and treatments
  • Soft tissue tumors and treatment
  • Amyloidosis: Diagnosis, Treatment, Outcomes

Hospital Universitario Río Hortega
2025

Hospital de Galdakao
2003-2020

Universidad de Zaragoza
2018

Osakidetza
1999

Hospital de Cruces
1992

The CURB-65 score (Confusion, Urea >7 mmol·L −1 , Respiratory rate ≥30·min low Blood pressure, and age ≥65 yrs) has been proposed as a tool for augmenting clinical judgement stratifying patients with community-acquired pneumonia (CAP) into different management groups. six-point was retrospectively applied in prospective, consecutive cohort of adult diagnosis CAP seen the emergency department 400-bed teaching hospital from March 1, 2000 to February 29, 2004. A total 1,100 inpatients 676...

10.1183/09031936.06.00062505 article EN European Respiratory Journal 2005-12-30
Thomas M. File Donald E. Low Paul B. Eckburg George H. Talbot H. David Friedland and 95 more Jon Lee Lily Llorens Ian A. Critchley Dirk Thye John Pullman Philip Giordano James Welker Paul Manos P. Mehra Thomas M. File Joana Espírito Santo B. Venkateswaralu C. G. Schrock William Tillis Jan A. Winetz Javier González Andrew G. Ramage Dwight D. Eisenhower Coenraad F.N. Koegelenberg Ingrid Engelbrecht Julie A. Jurgens Ismail Mitha J. Breedt Mashra Gani Jack Roos Marc D. Basson Louis van Zyl Ronel Meeding Muhammed Ameen Fulat M. Le Roux Pablo Bonvehí María Cristina Ganaha A. L. Gurini Gustavo Lopardo Laura Cristina Sergio Prieto Celestino Rodíguez Ricardo Teijeiro E Pallone Daniel Pryluka Clóvis Arns da Cunha N. B. da Silva António Freire Cláudia Starling J. Costa Fiterman Fernando Gôngora Rubio L. Carlos Losso Marco Patelli J. Souza Lima Paulo José Zimermann Teixeira Marta Moreira J. C. Abreu de Oliveira V. Roudas E. A. Gamal I. V. Leschenko В. А. Руднов A. G. Yevdokimova A. L. Vertkin Y. M. Ambalov I. V. Dvoryashina E. Zilber R. F. Khamitov A. N. Galustyan O. V. Reshetko Victoria Senior M. F. Grosan Gabriela Jimborean M. Lupse G. Aron Dan Olteanu Maria Puşchiță Claudia Gavriș V. M. Tudorache Vania Youroukova M Petkova E. Troshanova M. Dzhabalyan G Kavtaradze M. Makhviladze R. Tabukashvili Marco Pons Jorge Garbino Daniel Genné Madeleine Rothen J. O. de Saracho A. Capelastegui Rosario Menéndez Antoní Torres C. Shum Vicenç Falcó Emilio Bouza J.P. Bru Benoît Misset Bruno Mégarbane J.-P. Sollet

Ceftaroline, the active form of prodrug ceftaroline fosamil, is a novel cephalosporin with bactericidal activity against important pathogens associated community-acquired pneumonia (CAP), including Streptococcus pneumoniae and common Gram-negative pathogens. FOCUS 1 randomized, double-blinded, Phase III study that was conducted to evaluate efficacy safety fosamil in treating patients CAP. The primary objective determine non-inferiority [lower limit 95% confidence interval (CI) ≥ −10%]...

10.1093/jac/dkr096 article EN Journal of Antimicrobial Chemotherapy 2011-04-01

The aim of this study was to evaluate whether changes in regular physical activity (PA) affect health-related quality life (HRQoL) among patients with chronic obstructive pulmonary disease (COPD). 611 (mean age 67.2±8.4 yrs; forced expiratory volume 1 s 49.7±14.6) completed the St George's Respiratory Questionnaire (SGRQ), Chronic (CRQ) and Medical Outcomes Short Form (SF-36) questionnaire. PA, defined as patients' self-reported walking times, classified low, moderate high. After 5 yrs, 391...

10.1183/09031936.00021409 article EN European Respiratory Journal 2010-01-14

Processes of care and adherence to guidelines have been associated with improved survival in community-acquired pneumonia (CAP). In sepsis, bundles processes also increased survival. We aimed audit compliance guideline-recommended its impact on outcome hospitalised CAP patients sepsis. prospectively studied 4,137 13 hospitals. The evaluated were antibiotic prescription guidelines, first dose within 6 h oxygen assessment. Outcome measures mortality length stay (LOS). Oxygen assessment was...

10.1183/09031936.00188710 article EN European Respiratory Journal 2011-08-04

The aim of this study was to develop and validate a new method: classification regression tree (CART) based on easily accessible measures predict mortality in patients with stable chronic obstructive pulmonary disease (COPD). This prospective two independent cohorts: derivation cohort 611 recruited validation 348 patients, all followed for 5 yrs. CART analysis used 5-yr risk using the following covariates from cohort: age, % predicted forced expiratory volume 1 s (FEV(1)), dyspnoea, physical...

10.1183/09031936.00189010 article EN European Respiratory Journal 2011-05-12

The current authors developed a new prediction rule based on the five risk classes defined by Pneumonia Severity Index to identify allocation of inpatient care in community-acquired pneumonia. decision hospitalise low-risk (I−III) was unquestionable, if presence one or more following were evident: arterial oxygen tension <8.0 kPa (60 mmHg), shock, decompensated coexisting illnesses, pleural effusion, inability maintain oral intake, social problem, and lack response previous adequate...

10.1183/09031936.03.00057302 article EN European Respiratory Journal 2003-04-01

Background: Chronic obstructive pulmonary disease (COPD) is usually assessed using FEV 1 to establish the diagnosis and severity of disease. However, COPD now considered a systemic

10.1093/qjmed/hcl110 article EN QJM 2006-09-06

BACKGROUND: Whether Q fever responds better to doxycycline or erythromycin is unknown. METHODS: The efficacy of and in the treatment pneumonia due was assessed a prospective, randomised, double blind study 82 patients with diagnosis features suggestive infection; 48 proved have fever. Of 48, 23 received 100 mg twice day 25 500 six hourly, both for 10 days. RESULTS: Both groups had similar demographic characteristics. Fever showed more rapid reduction group (3(1.6) days versus 4.3(2) days)....

10.1136/thx.47.4.276 article EN Thorax 1992-04-01

Background.Hospitalizations due to pneumonia increase steadily with age. The purpose of this study is explore differences in host- and pathogen-related factors, process care, outcome as a function age elderly patients bacteremic pneumococcal identify factors related mortality.

10.1093/gerona/glt288 article EN The Journals of Gerontology Series A 2014-01-27

<h3>Background:</h3> Although patients admitted to hospital for community-acquired pneumonia (CAP) experience substantial short-term mortality following discharge, few studies have focused on identifying factors that predict after admission in this population. The objective of study was develop and validate a prognostic index 90-day discharge among with CAP. <h3>Methods:</h3> derived 1117 adult discharged between 2003 2007 from general It validated 646 consecutive CAP three other hospitals 1...

10.1136/thx.2008.098814 article EN Thorax 2009-02-22

We describe an immunocompetent patient with a solitary brainstem abscess that responded to antituberculous therapy. Although prompt surgical therapy has been advocated, the possibility of medical resolution tuberculous abscesses should be considered.

10.1212/wnl.49.1.265 article EN Neurology 1997-07-01
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