A5101846378- Advanced biosensing and bioanalysis techniques
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- CRISPR and Genetic Engineering
- Hearing, Cochlea, Tinnitus, Genetics
- Impact of Light on Environment and Health
- Land Use and Ecosystem Services
- SARS-CoV-2 and COVID-19 Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Liver Disease Diagnosis and Treatment
- Computational Drug Discovery Methods
- EEG and Brain-Computer Interfaces
- Organ Transplantation Techniques and Outcomes
- Hepatitis C virus research
- Cardiac Arrest and Resuscitation
- Liver Disease and Transplantation
- Hepatitis B Virus Studies
- RNA Research and Splicing
- Peptidase Inhibition and Analysis
- Reproductive Biology and Fertility
- RNA Interference and Gene Delivery
- DNA and Nucleic Acid Chemistry
- Autophagy in Disease and Therapy
- Human Mobility and Location-Based Analysis
- Traumatic Brain Injury Research
Nanjing Drum Tower Hospital
2022-2025
University of Warwick
2025
Chongqing Medical University
2023-2025
Dalian Medical University
2024-2025
Second Affiliated Hospital of Chongqing Medical University
2024-2025
Jiujiang First People's Hospital
2025
Beijing Hua Xin Hospital
2024-2025
Wuhan Polytechnic University
2025
Yangzhou University
2023-2024
Guangdong Academy of Medical Sciences
2022-2024
This study set out to develop a computed tomography (CT)-based wavelet transforming radiomics approach for grading pulmonary lesions caused by COVID-19 and validate it using real-world data.This retrospective analyzed 111 patients with 187 from 16 hospitals; all had confirmed underwent non-contrast chest CT. Data were divided into training cohort (72 127 nine hospitals) an independent test (39 60 seven according the hospital in which CT was performed. In all, 73 texture features extracted...
The high-resolution spacecraft poses an urgent need for opto-mechanical structure with ultra-high stability and light-weight. Owing to the advantages of both carbon fiber-reinforced carbon-based composites (C/C composites) honeycomb sandwich structure, a novel C/C strategy is proposed in this study. It was fabricated by using weaving fabrics Chemical Vapor Infiltration (CVI) process, then tested under out-of-plane compression. Taking weave wall, anisotropy characteristics damage mechanism...
Highlights•miR-1825 is upregulated in CRC and associated with progression•circTBC1D22A functions as an efficient miR-1825 sponge cells•ATG14 functional target of cells•circTBC1D22A regulates autophagy via miR-1825/ATG14 axisSummaryDistant metastasis the main cause death patients colorectal cancer (CRC). A better understanding mechanisms can greatly improve outcome CRC. Accumulating evidence suggests that circRNA plays pivotal roles progression metastasis, especially acting a miRNA to...
Abstract Although human females appear be at a higher risk of concussion and suffer worse outcomes than males, underlying mechanisms remain unclear. With increasing recognition that damage to white matter axons is key pathologic substrate concussion, we used clinically relevant swine model explore potential sex differences in the extent axonal pathologies. At 24 h post-injury, female displayed greater number swollen profiles more widespread loss sodium channels males. Axon degeneration for...
Cervical cancer is one of the deadliest cancers that pose a significant threat to women's health. Early detection and treatment are commonly used methods prevent cervical cancer. The use pathological image analysis techniques for automatic interpretation cells in slides prominent area research field digital medicine. According Bethesda System, cytology necessitates further classification precancerous lesions based on positive interpretations. However, clinical definitions among different...
Revealing the clinical manifestations and associations of COVID-19 before after negative transition remains an area significant uncertainty. The aim this study is to investigate characteristics observed during Omicron infection among a specific population, namely healthcare workers (HCWs). From November 4, 2022, January 15, 2023, HCWs in our hospital were enrolled document symptoms, prevention, treatment for using structured questionnaire. A total 1101 included, with SARS-CoV-2 detected...
Mother-to-child transmission (MTCT) is one of the main routes HBV, and previous studies focused on efficacy safety nucleoside analogues (NAs) in preventing MTCT. There are limited data virologic changes chronic hepatitis B (CHB) patients after discontinuing treatment postpartum retreatment. A retrospective-prospective real-world pilot cohort study pregnant women with CHB was conducted. Biochemical virological characteristics (HBsAg, HBeAg HBV DNA) received NAs pre-pregnancy (n = 24),...
Hypothesis In this study, we aimed to examine the cochlear expression pattern and function of Striatin-interacting protein 2 (STRIP2) by using animal models. Background Sensorineural hearing loss often results from genetic defects in hair cell (HC) development function. STRIP2 is a part striatin-interacting phosphatase kinase (STRIPAK) complex, which plays important regulatory roles fate determination, proliferation, cytoskeletal organization, morphology. A recent study revealed Strip2 as...
Government reimbursement negotiation (GRN) is an important policy tool to increase the accessibility of drugs. In China, impact GRN implementation on programmed death-1 (PD-1) drugs price, procurement volume, and expenditure unknown. This study used a multiple-treatment period interrupted time series design covering from first-time recorded in Chinese Medical Economic Information database 2022 examine changes hospital volume PD-1 after China. Data were obtained 698 public hospitals 30...
To solve the missed and wrong detection problems of object model in identifying soybean companion weeds, this paper proposes an enhanced multi-scale channel feature based on RT-DETR (EMCF-RTDETR). First, we designed a lightweight hybrid-channel extraction backbone network, which consists CGF-Block module FasterNet-Block working together, aiming to reduce amount computation number parameters while improving efficiency extraction. Second, constructed EA-AIFI module. This enhances detailed...
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignant tumors with a poor prognosis. Type X collagen α 1 chain (COL10A1), member family, gene associated progression variety human tumors, but specific function and molecular mechanism COL10A1 in pancreatic cancer remain unclear. Our study found that highly expressed cells tissues, its high expression related to prognosis some clinicopathological features, such as tumor size differentiation. Biological functional...
Undetectable occult liver metastases block the long-term survival of pancreatic ductal adenocarcinoma (PDAC). This study aimed to develop a radiomics-based model predict and assess its prognostic capacity for survival.
Abstract Since the release of ChatGPT in 2022, AI-generated texts have inevitably permeated various types writing, sparking debates about quality and quantity content produced by such large language models (LLM). This study investigates a critical question: Have from LLM infiltrated realm scientific if so, to what extent setting? By analyzing dataset comprised preprint manuscripts uploaded arXiv, bioRxiv, medRxiv over past two years, we confirmed quantified widespread influence publications...