- Pancreatic and Hepatic Oncology Research
- Economic and Financial Impacts of Cancer
- Folate and B Vitamins Research
- Alzheimer's disease research and treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Neuroblastoma Research and Treatments
- Cholinesterase and Neurodegenerative Diseases
- Probiotics and Fermented Foods
- Cardiac tumors and thrombi
- Kruppel-like factors research
- Anesthesia and Neurotoxicity Research
- Cancer, Stress, Anesthesia, and Immune Response
- Ginkgo biloba and Cashew Applications
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease Diagnosis and Treatment
- Case Reports on Hematomas
- Inflammation biomarkers and pathways
- Cardiac, Anesthesia and Surgical Outcomes
- Autophagy in Disease and Therapy
- Healthcare and Venom Research
- Cervical Cancer and HPV Research
- Biochemical Analysis and Sensing Techniques
- Lipid metabolism and disorders
- Cannabis and Cannabinoid Research
- Liver Disease and Transplantation
Zhejiang Center for Disease Control and Prevention
2024
Tung Wah Hospital
2020-2021
Sun Yat-sen University
2021
Jiangsu Province Hospital
2020
Affiliated Hospital of Southwest Medical University
2019
Luoyang Central Hospital Affiliated to Zhengzhou University
2019
Hong Kong University of Science and Technology
2018
Shenyang Pharmaceutical University
2017
Sichuan University
2016
West China Hospital of Sichuan University
2016
Tight junction is a structural constitution in cell-cell adhesion and play an important role the maintenance of permeability integrity normal epithelial cell barrier. The protein encoded by Claudin 1 (CLDN1), member claudin family, integral membrane component tight strands. CLDN1 has been proved to regulate proliferation metastasis multiple tumors, but little known about its esophageal squamous carcinoma (ESCC). Here, we found that was aberrantly increased ESCC tissues lines, mainly...
This study presents a new technique for determining vitamin B12 in milk powder using high-performance liquid chromatography-inductively coupled plasma mass spectrometry (HPLC-ICP-MS). We used ultrasonics with potassium ferrocyanide and zinc acetate solutions to extract the samples. 59Co was employed as analytical target cyanocobalamin. It separated Phenomenex Luna 5 μm C18 (250 × 4.6 mm) chromatographic column mobile phase consisting of 1.6 mmol/L EDTA 0.4 KH2PO4 60% v/v methanol solution...
Retroperitoneal fibrosis (RPF) is an uncommon disease that characterized by development of fibrosclerotic tissues involving retroperitoneal structures. This study aimed to investigate the clinical features 30 patients with RPF in a single center Beijing 10-year period.We retrospectively analyzed data on demographic characteristics, manifestations, laboratory findings, radiological modalities treatments, outcomes and prognosis RPF. Patients were treated Chao-Yang Hospital between January 2003...
The incidence of young patients with pancreatic cancer (PC) is on the rise, and there a lack models that could effectively predict their prognosis. purpose this study was to construct nomograms for predicting overall survival (OS) cancer-specific (CSS) PC.PC younger than 50 years old from 2004 2015 in Surveillance, Epidemiology, End Results (SEER) database were selected randomly divided into training set validation set. Univariable forward stepwise multivariable Cox analysis used determine...
Cerebral venous thrombosis (CVT) is a rare but life-threatening disease in pregnant women. Anticoagulation the first-line therapy for CVT management. However, some patients have poor outcomes despite anticoagulation. Currently, endovascular treatment of women remains controversial. We report case woman who was successfully treated with two stent retriever devices.The patient 29-year-old woman. She first diagnosed hyperemesis gravidarum due to severe nausea and vomiting one week. As...
The incidence of pancreatic neuroendocrine tumors (PNETs) has increased significantly. purpose this study was to analyze the clinical characteristics and prognosis patients under 50 years old.Patients with PNETs recorded in Surveillance, Epidemiology, End Results (SEER) database from 2004 2015 were analyzed. analyzed by Chi-square test. Kaplan-Meier method used estimate overall survival (OS). Multivariate Cox proportional risk regression analysis determine independent prognostic...
To investigate the neuroprotective effect and mechanism of DL-3-n-butylphthalide (NBP) on brain-derived neurotrophic factor (BDNF)/tyrosine kinase B (TrkB) its downstream signalling pathway after cerebral ischemia/reperfusion injury (CIRI) in rats.The middle artery occlusion/reperfusion (MCAO/R) model was used. Reperfusion performed 2 h ischemia, 20 mg/kg NBP intraperitoneally injected. Neurological defect score pathological changes were performed. Apoptotic cells detected using situ...
Amyloid depositions in the brain represent characteristic hallmarks of Alzheimer's disease (AD) pathology. The abnormal accumulation extracellular amyloid-beta (Aβ) and resulting toxic amyloid plaques are considered to be responsible for clinical deficits including cognitive decline memory loss. In vivo two-photon fluorescence imaging live AD mouse model through a chronic window (thinned skull or craniotomy) provides mean greatly facilitate study pathological mechanism owing its high spatial...
Objective To explore the quality of life (QoL) among female condyloma acuminatum patients.Methods 118 patients were interviewed face-to-face by well-trained nurses with questionnaire including SF-36 Chinese version,the t-test and x2 test used to compare scale scores SF36 between patient control groups.Results There 101 eligible questionnaire,the physical function(PF) bodily pain(BP) highest in group,the score was (92.9 ± 10.5)points (75.0 1 1.2) points,respectively.Role limitations due...
Objective To study and analyze the effects of tiatoxonium bromide noninvasive positive pressure ventilation on blood gas analysis, inflammatory factors adiponectin (APN), superoxide dismutase (SOD) prealbumin (PAB) levels in elderly patients with chronic obstructive pulmonary disease (COPD) respiratory failure. Methods Eighty-two COPD failure admitted to our hospital from February 2017 2018 were studied.They divided into experimental group control according random number table...
Objective To explore the correlation between rs4680 polymorphic site of catechol-O-methyl transferase (COMT) gene and postoperative pain so as to provide theoretical evidence for individualized medicine. Methods A total eighty -three patients [aging 29-58, American Society Anesthesiologists (ASA) Ⅰ or Ⅱ] scheduled mastectomy under general anesthesia was selected. Polymerase chain reaction- restriction fragment length polymorphism (PCR-RFLP) adopted identify their genotype COMT. The...