A5018315817- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cancer Immunotherapy and Biomarkers
- Asthma and respiratory diseases
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Diagnosis and treatment of tuberculosis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pulmonary Hypertension Research and Treatments
- RNA modifications and cancer
- Inhalation and Respiratory Drug Delivery
- Venous Thromboembolism Diagnosis and Management
- Gas Sensing Nanomaterials and Sensors
- Infectious Diseases and Tuberculosis
- Lung Cancer Research Studies
- Advanced Chemical Sensor Technologies
- Tuberculosis Research and Epidemiology
- Cancer Genomics and Diagnostics
- Pediatric health and respiratory diseases
- Medical Imaging and Pathology Studies
- Shoulder Injury and Treatment
- Respiratory Support and Mechanisms
- Long-Term Effects of COVID-19
- Ion Transport and Channel Regulation
Hospital Del Mar
2016-2025
Universitat Pompeu Fabra
2016-2024
Hospital del Mar Research Institute
2016-2024
Municipal Institute for Medical Research
2016-2024
Instituto de Salud Carlos III
2016-2021
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2014-2021
Parc de Salut
2016-2018
John Wiley & Sons (United States)
2018
Barcelona Biomedical Research Park
2018
Virginia Commonwealth University
2018
Introduction Immunotherapy is firmly established as a treatment regimen in various solid tumors, driven by its exceptional benefits selected group of patients. Despite widespread adoption immune checkpoint blockade (ICB) across diverse the quest for clinically informative biomarker long-term benefit remains unmet.
Chronic thromboembolic pulmonary disease (CTEPD) consists of persistent vascular obstruction on imaging and involves long-term functional limitations, with or without chronic hypertension (CTEPH). The aim this study was to evaluate the incidence risk factors both defects CTEPH after hospitalization in patients COVID-19 PE during a 2-year follow-up.
Abstract Chronic obstructive pulmonary disease (COPD) is a chronic and often progressive disorder with heterogeneous presentation frequent systemic manifestations. Several aspects like persistence in smoking habit, continuous exacerbations, alpha-1-antitrypsin deficiency inflammatory-immune response, are involved the pathophysiology progression of disease. However, role natural killer (NK) cells remains controversial. Otherwise, human cytomegalovirus (HCMV) infection has been reported to...
Abstract Background Supplemental oxygen delivered with standard therapy (SOT) improves exercise capacity in patients idiopathic pulmonary fibrosis (IPF). Although high-flow nasal cannula (HFNC) oxygenation other respiratory diseases, its impact on performance has never been evaluated IPF patients. We hypothesized that HFNC may improve subjects compared to SOT. Methods This was a prospective, crossover, pilot randomized trial both methods during constant submaximal cardiopulmonary test (CPET)...
Different clinical predictors of physical activity (PA) have been described in idiopathic pulmonary fibrosis (IPF), but studies are lacking evaluating the potential role muscle strength and anxiety depression symptoms PA limitation. Moreover, little is known about impact changes course disease. The aim present study was to investigate relationship between baseline a wide range variables IPF, assess its longitudinal at 12 months on progression free-survival.PA assessed by accelerometer...
More than 60% of patients with lung cancer are diagnosed at advanced stages. The introduction targeted therapies requires molecular diagnosis to guide treatment. aim this study was evaluate the feasibility performing mutational analysis brushing specimens obtained by radial-miniprobe endobronchial ultrasound (R-EBUS) plus fluoroscopy-guided bronchoscopy in peripheral pulmonary adenocarcinoma.Brushing were deposited on cytological slides and conserved Roswell Park Memorial Institute (RPMI)...
Tumor recurrence is frequent and survival rates remain extremely low in lung adenocarcinoma (ADC). We hypothesize that carcinogenic factors will promote loco-regional modifications not only the future tumor, but throughout exposed lung. Objective: To analyze whether most prevalent mutations observed ADC can also be non-neoplastic tissue, as well short-term prognosis implications of this finding. Methods: Non-tumoral parenchyma specimens obtained during surgery from 47 patients with EGFR...
Abstract Background Diaphragm fiber atrophy has been evidenced after short periods of mechanical ventilation (MV) and related to critical illness-associated diaphragm weakness. Atrophy is described as a decrease in cross-sectional area (CSA) human biopsy, but samples are still difficult obtain clinics. In recent years, ultrasound become useful tool intensive care evaluate anatomy. The present study aimed the ability expiratory thickness (Tdi) measured by predict atrophy, defined CSA obtained...
Background: Hypercapnic encephalopathy is relatively frequent in severe exacerbations of COPD (ECOPDs), with its intensity usually being evaluated through clinical scales. Bispectral index (BIS) a new technique, based on the analysis electroencephalographic signal, which provides good approximation to level consciousness, having already been validated anesthesia. Objective: The objective study was evaluate utility BIS assessment hypercapnic ECOPD patients. Patients and methods: A total ten...
Lung cancer is a malignant tumor with high morbidity and mortality worldwide. At present, the main treatment methods for patients advanced non-small cell lung (NSCLC) include molecular targeted therapy immunotherapy. The efficacy rate of immune checkpoint inhibitor (ICI) monotherapy relatively low. Studies have confirmed that some combination therapies better anti-tumor higher response rates, such as PD-1/PD-L1 inhibitors combined chemotherapy or therapy. Poly (ADP-ribose) polymerase (PARP)...