- Particle accelerators and beam dynamics
- Particle Accelerators and Free-Electron Lasers
- Superconducting Materials and Applications
- Nuclear Physics and Applications
- Magnetic confinement fusion research
- Plasma Diagnostics and Applications
- Protein purification and stability
- Monoclonal and Polyclonal Antibodies Research
- Enzyme Structure and Function
- Protein Structure and Dynamics
- Gyrotron and Vacuum Electronics Research
- Viral Infectious Diseases and Gene Expression in Insects
- Electrostatic Discharge in Electronics
- Fuel Cells and Related Materials
- Bacterial Genetics and Biotechnology
- ATP Synthase and ATPases Research
- Spacecraft and Cryogenic Technologies
- Fusion materials and technologies
- Mitochondrial Function and Pathology
- Particle Detector Development and Performance
- Electron and X-Ray Spectroscopy Techniques
- Vacuum and Plasma Arcs
- Enzyme Production and Characterization
- Scientific Research and Discoveries
- Protein Interaction Studies and Fluorescence Analysis
Brookhaven National Laboratory
2006-2024
Argonne National Laboratory
2024
Array BioPharma (United States)
2020
Cell Biotech (South Korea)
2020
Amgen (United States)
2018
Brookhaven College
2004-2013
National Library of Luxembourg
2007
RIKEN BNL Research Center
1993-2006
High Energy Accelerator Research Organization
2004
European Organization for Nuclear Research
2004
A metal-binding site consisting of two histidines positioned His-X3-His in an alpha-helix has been engineered into the surface Saccharomyces cerevisiae iso-1-cytochrome c. The synthetic cytochrome c retains its biological activity vivo. Its ability to bind chelated Cu(II) characterized by partitioning aqueous two-phase polymer systems containing a polymer-metal complex, Cu(II)IDA-PEG, and metal-affinity chromatography. stability constant for complex formed between Cu(II)IDA-PEG is 5.3 x...
Abstract The fifth modeling workshop (5MW) was held in June 2023 at Favrholm, Denmark and sponsored by Recovery of Biological Products Conference Series. goal the to assemble practitioners review discuss current state, progress since last fourth mini (4MMW), gaps opportunities for development, deployment maintenance models bioprocess applications. Areas focus were four categories: biophysics molecular modeling, mechanistic computational fluid dynamics (CFD) plant modeling. Highlights...
Crystallographic data for three different protein crystals (glycogen phosphorylase b to 2 Å resolution, β -lactamase I 2.5 resolution and troponin C 6 resolution) have been recorded using the intense synchrotron radiation beam emitted by DCI storage ring at LURE DORIS DESY/EMBL. Reduction in exposure times of approximately 50-fold an increase crystal lifetime least fivefold are observed when compared with those a conventional rotating-anode source. These factors made possible collection...
A half-cell superconducting rf electron gun is designed to provide 0.5 A, 2 MeV beam for the Brookhaven National Laboratory R Energy Recovery Linac. Total power of 1 MW must be delivered meet current and energy specifications, resulting in very strong coupling. Two opposing fundamental couplers (FPCs) are employed minimize transverse kick traversing structure halve through coupler. single-window coaxial coupler has been average coupling requirements. The features a planar beryllia window...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRuthenium-mediated protein cross-linking and stabilizationAndreas Muheim, Robert J. Todd, Danilo R. Casimiro, Harry B. Gray, Frances H. ArnoldCite this: Am. Chem. Soc. 1993, 115, 12, 5312–5313Publication Date (Print):June 1, 1993Publication History Published online1 May 2002Published inissue 1 June 1993https://pubs.acs.org/doi/10.1021/ja00065a060https://doi.org/10.1021/ja00065a060research-articleACS PublicationsRequest reuse permissionsArticle...
The Coherent Electron Cooling Proof of Principle (CeC PoP) system is being installed in the Relativistic Heavy Ion Collider (RHIC) at Brookhaven National Laboratory. It will demonstrate ability relativistic electrons to cool a single bunch heavy ions RHIC. This technique may increase beam luminosity by as much tenfold. Within scope this experiment, 112 MHz 2 MeV Superconducting Radio Frequency (SRF) electron gun coupled with cathode stalk mechanism, two normal conducting 500 single-cell...
The inner surface of the ring vacuum chambers US Spallation Neutron Source (SNS) will be coated with /spl sim/100 nm Titanium Nitride (TiN). This is to minimize secondary electron yield (SEY) from chamber wall, and thus avoid so-called e-p instability caused by multipacting as observed in a few high-intensity proton storage rings. Both DC sputtering DC-magnetron were conducted test relevant geometry SNS chambers. Auger Electron Spectroscopy (AES) Rutherford Back Scattering (RBS) used analyze...
The physics interest in a luminosity upgrade of RHIC requires the development cooling-frontier facility. Detailed calculations were made electron cooling stored beams. This has been followed by beam dynamics simulations to establish feasibility creating necessary beam. accelerator will be superconducting Energy Recovery Linac (ERL). An intensive experimental R&D program engages various elements accelerator, as described 24 contributions 2007 PAC.
The stainless steel vacuum chambers of the 248 m accumulator ring Spallation Neutron Source are to be coated with ∼100 nm titanium nitride (TiN). This is minimize secondary electron yield from chamber wall, and thus avoid so-called e–p instability caused by multipacting as observed in a few high-intensity proton storage rings. Reports literature suggest that TiN coating, acting hydrogen permeation barrier, may also reduce ultimate outgassing rate. rate deposited at various sputtering...
With the 3 GeV electron beam energy for National Synchrotron Light Source II (NSLS-II) ring, only superconducting wigglers (SCW) producing greater than 4T peak field can cover photon range of 20 keV and 200 with sufficient number photons. The High Engineering X-ray (HEX) Diffraction beamline, which is primarily funded by New York State Energy Research Development Authority (NYSERDA) NSLS-II, will be equipped a 1.2m-long SCW 70 mm period length 4.3 T on-axis field. This free from use liquid...