- Particle Accelerators and Free-Electron Lasers
- Particle accelerators and beam dynamics
- Gyrotron and Vacuum Electronics Research
- Superconducting Materials and Applications
- Acute Myeloid Leukemia Research
- Multimedia Communication and Technology
- Advanced X-ray Imaging Techniques
- Hematopoietic Stem Cell Transplantation
- Digital Rights Management and Security
- Video Analysis and Summarization
- Pelvic floor disorders treatments
- Electromagnetic Simulation and Numerical Methods
- Hematological disorders and diagnostics
- Magnetic confinement fusion research
- Acoustic Wave Resonator Technologies
- Advanced Multi-Objective Optimization Algorithms
- Computability, Logic, AI Algorithms
- Information and Cyber Security
- Expert finding and Q&A systems
- Cybercrime and Law Enforcement Studies
- Lymphoma Diagnosis and Treatment
- Menopause: Health Impacts and Treatments
- AI in cancer detection
- Gaussian Processes and Bayesian Inference
- Immune Cell Function and Interaction
Brookhaven National Laboratory
2016-2025
The Ohio State University
2024
Lung Institute
2024
Imperial College London
2024
Argonne National Laboratory
2024
Prisma Health
2021
University of South Carolina
2021
Provincia autonoma di Bolzano - Alto Adige
2021
Ospedale di Bolzano
2021
Proteogenomics Research Institute for Systems Medicine
2021
The primary diagnosis of non-Hodgkin lymphoma/leukemia by fine-needle aspiration (FNA) is still controversial and relatively underused. We evaluated our FNA experience with lymphomas using the revised European-American classification lymphoid neoplasms to determine reliability when combined flow cytometry in lymphoma, types diagnoses made, limitations this technique. Slides reports from all lymph node extranodal FNAs performed during period January 1, 1993, December 31, 1998, a lymphoma or...
With the aid of machine learning techniques, genetic algorithm has been enhanced and applied to multi-objective optimization problem presented by dynamic aperture National Synchrotron Light Source II (NSLS-II) Storage Ring. During evolution processes employed algorithm, population is classified into different clusters in search space. The with top average fitness are given ``elite'' status. Intervention on implemented repopulating some potentially competitive candidates based experience...
A measurable chaos indicator is used as the online optimization objective in tuning a complicated nonlinear system—the National Synchrotron Light Source-II storage ring. Through analyzing Shannon entropy measured Poincaré maps, not only can commonly characterizations be extracted, but more importantly, quantified and then for an regularization of these maps. The method itself general applicable to other tunable systems well. Published by American Physical Society 2025
Abstract In this study we assess a flow cytometric gating method and its correlation with concurrent manual bone marrow differential in abnormal marrows. Like normal cells, leukemic blasts fall into discrete areas when cytogram of CD 45 expression Right Angle Light Scatter is plotted Log scale. We studied 50 specimens suspected diagnosis leukemia. Gates were set on the eight clusters typically found marrow. employed these gates to determine Our results show high between following r values:...
Menopause is presumed to have a causative role in the development of female urinary incontinence. While some clinical trials shown that estrogen can affect tract function, our knowledge pathophysiologic changes resulting from menopause and hormone replacement therapy poor. The cynomolgus monkey well-established model for study therapy, particularly cardiovascular arena. We utilized this animal determine histologic effects estrogen/progestin proximal urethra vagina. Estrogen induced an...
Stroke is known to affect both men and women; however, incidence outcomes differ between them. Therefore, the discovery of novel, sex-specific, blood-based biomarkers for acute ischemic stroke (AIS) patients has potential enhance understanding etiology this deadly disease in content sex. The objective study was identify serum metabolites associated with male female AIS patients.Metabolites were measured use untargeted, reverse-phase ultra-performance liquid chromatography-tandem mass...
With a Bayesian Gaussian regression approach, systematic method for analyzing storage ring's beam position monitor (BPM) system requirements has been developed. The ultimate performance of ring-based accelerator, based on brightness or luminosity, is determined not only by global parameters, but also local properties at some particular points interest (POI). BPMs used monitoring the properties, however, can be located these points. Therefore, underlying and fundamental purpose BPM to predict...
In this paper, we applied an approximate entropy (ApEn) analysis to nonlinear beam dynamics. Due the presence of strong magnets, degree chaos in motion gradually increases proportionally with its amplitude. Such can be quantitatively characterized ApEn turn-by-turn readings. is a technique used quantify amount regularity and unpredictability fluctuations respect time-series data. The ApEn, when as indicator, then for lattice optimization analysis. National Synchrotron Light Source II...
Abstract Background * In the United Kingdom, there are one million people suffering from heart failure (HF), with more than 60,000 new cases annually (1). Monitoring for declining left ventricular ejection fraction (LVEF) could optimise treatment approaches and avert healthcare episodes. Easy home-based tracking of cardiac function would be transformative. Previous studies have validated capability artificial intelligence-enabled electrocardiogram (AI-ECG) to correlated changes in LVEF (2)....
With a Bayesian approach, the linear optics correction algorithm for storage rings is revisited. Starting from Bayes' theorem, complete model simplified as "likelihood functions" and "prior probability distributions". Under some assumptions, least square then Jacobian matrix approach can be re-derived. The coherence of ensured through specifying self-consistent regularization coefficient to prevent overfitting. Optimal weights different objectives are obtained based on their measurement...
Navy fleets have a defined overall objective for mission readiness impacted by the health of personnel aboard ships. Medical treatment facilities on ships determines degree readiness. This paper describes concepts and technologies necessary to establish Naval telemedicine system, which can drastically improve care delivery. It consists various combinations following components: Fleet Consultation Diagnostic Centers, Shipboard Centers (hospital ship or combatant with medical specialists...
For some synchrotron light source beamline applications, a round beam is preferable to flat one. A conventional method of obtaining in an electron storage ring shift its tune close linear difference resonance. The linearly coupled dynamics analyzed with perturbation theories, which have certain limitations. In this paper, we adopt the Solution by LInear Matrices (SLIM) analysis calculate exact sizes design lattices. SLIM can deal generally accelerator lattice. effects various coupling...
This study proposes using an established common body of knowledge (CBK) as one means organizing information security literature. Consistent with calls for more relevant systems (IS) research, this industrydeveloped framework can motivate future research towards topics that are important to the practitioner. In review, forty-eight articles from ten IS journals 1995 2004 selected and cross-referenced domains CBK. Further, we distinguish empirical frameworks, or tutorials. Generally, identified...
Methods of characterization a storage ring's lattice have traditionally been intrusive to routine operations. More importantly, the seen by particles can drift with beam current due collective effects. To circumvent this, we developed novel approach for dynamically characterizing that is transparent Our adopts dedicated filling pattern which has short, separate diagnostic bunch train (DBT). Through use bunch-by-bunch feedback system, DBT be selectively excited on demand. Gated functionality...
This paper explores the usage of a just in time knowledge management system. Based on an expert's digital trace, system is able to request their support providing answers problems others have posted. Siemens' TechnoWeb used as case study demonstrate such Knowledge indispensable asset corporations, and increasing productivity worker important challenge 21st century. As such, systems (KMS) play crucial role. Siemens has combined corporate social media platform, networking formerly isolated...
The National Synchrotron Light Source II (NSLS-II) is a state of the art 3 GeV third generation light source at Brookhaven Laboratory. During spring/ summer 2014, storage ring was commissioned up to 50 mA without insertion devices. In fall we began commissioning project beamlines, which included seven devices on six ID ports. Beamlines IXS, HXN, CSX-1, CSX-2, CHX, SRX, and XPD-1 consist elliptically polarized undulator (EPU), damping wigglers (DW) in-vacuum undulators (IVU) covering from VUV...
Abstract In this paper we present an expansion of the technique characterizing nonlinear optics from off-energy orbits (NOECO) [1] to cover harmonic sextupoles in storage rings. The existing NOECO has been successfully used correct chromatic sextupole errors on MAX-IV machine, however, it doesn’t account for sextupoles, which are widely many other machines. Through generating vertical dispersion with skew quadrupoles, a measurable dependence can be observed hybrid horizontal and dispersive...