Luigi Caputi
A5068023927- Acute Ischemic Stroke Management
- Moyamoya disease diagnosis and treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Connective tissue disorders research
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Pancreatic and Hepatic Oncology Research
- Stroke Rehabilitation and Recovery
- Cerebrovascular and genetic disorders
- Williams Syndrome Research
- Long-Term Effects of COVID-19
- Neurological Disorders and Treatments
- Neurological Complications and Syndromes
- Intensive Care Unit Cognitive Disorders
- Intracranial Aneurysms: Treatment and Complications
- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
Azienda Ospedaliera Ospedale Maggiore
2024
Fondazione IRCCS Istituto Neurologico Carlo Besta
2018-2019
Lombardy was severely hit by the COVID-19 pandemic since February 2020 and Health System underwent rapid reorganization. Outpatient clinics were stopped for non-urgent patients: it became a priority to manage hundreds of fragile neurological patients who suddenly had less reference points. In Italy, before pandemic, Televisits neither recognized nor priced. At Fondazione IRCCS Istituto Neurologico C. Besta, we reorganized outpatient deliver Neuro-telemedicine services, including...
Background The optimal treatment for acute minor ischemic stroke is still undefined. and options include dual antiplatelet (DAPT), intravenous thrombolysis (IVT), or their combination. We aimed to investigate benefits risks of combining IVT DAPT versus alone in patients with MIS. Methods Results This a prespecified propensity score‐matched analysis from prospective multicentric real‐world study (READAPT [Real‐Life Study on Short‐Term Dual Antiplatelet Treatment Patients With Ischemic Stroke...
Background: According to the literature, about one third of patients with brain ischemic symptoms lasting <24 h, which are classified as Transient attacks (TIAs) according traditional “time-based” definition, show presence acute lesions at neuroimaging. Recent evidence has shown that neuroimaging may impact on outcome transient treated dual antiplatelet treatment (DAPT). This uncertainty is even more compelling in recent years short-term DAPT become standard for any non-cardioembolic TIA...
Moyamoya angiopathy (MA) is a cerebrovascular disease determining progressive stenosis of the terminal part internal carotid arteries (ICAs) and their proximal branches compensatory development abnormal "moyamoya" vessels. MA occurs as an isolated cerebral (so-called moyamoya disease) or in association with various conditions (moyamoya syndromes) including several heritable such Down syndrome, neurofibromatosis type 1 other genomic defects. Although mechanism that links to these genetic...
Introduction: Clinical presentation and genetic profile of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are highly variable, hampering their management. Sequencing circulating tumor DNA from liquid biopsy (LB) has been proposed as a less invasive alternative to solid (SB). Our aim was compare the mutational (MP) provided by LB with that deriving SB in GEP-NETs. Methods: were derived simultaneously 6 GEP-NET patients. A comparative targeted next-generation sequencing (NGS) analysis...
Sex may impact clinical outcomes in patients with stroke treated dual antiplatelet therapy (DAPT). We aimed to investigate the sex differences short-term of DAPT within a real-world population noncardioembolic mild-to-moderate ischemic or high-risk transient attack. performed propensity score-matched analysis from prospective multicentric cohort study (READAPT [Real-Life Study on Short-Term Dual Antiplatelet Treatment Patients With Ischemic Stroke Transient Attack]) by including (National...