A5067634137- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Cardiac tumors and thrombi
- Cardiac Arrhythmias and Treatments
- Transplantation: Methods and Outcomes
- Cardiac Structural Anomalies and Repair
- Aortic Disease and Treatment Approaches
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Function and Risk Factors
- Cardiac Ischemia and Reperfusion
- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Cardiovascular Effects of Exercise
- Traumatic Brain Injury and Neurovascular Disturbances
- Pulmonary Hypertension Research and Treatments
- Cardiovascular Disease and Adiposity
- Nitric Oxide and Endothelin Effects
- Cardiovascular Issues in Pregnancy
- SARS-CoV-2 and COVID-19 Research
- Cardiac pacing and defibrillation studies
- COVID-19 Clinical Research Studies
- Thermal Regulation in Medicine
- Infectious Aortic and Vascular Conditions
- Atrial Fibrillation Management and Outcomes
- Sarcoidosis and Beryllium Toxicity Research
Duke Medical Center
2009-2024
Duke University Hospital
2006-2024
Duke University
1995-2024
Mayo Clinic in Arizona
2020
University of Padua
2020
Children's Hospital of Philadelphia
1996
Durham University
1995-1996
Nonimmunogenic, tissue-engineered vascular grafts stored long-term maintain their patency, strength, and function after transplant in large-animal models.
Abstract The microbiology, epidemiology, diagnostics, and treatment of infective endocarditis (IE) have changed significantly since the Duke Criteria were published in 1994 modified 2000. International Society for Cardiovascular Infectious Diseases (ISCVID) convened a multidisciplinary Working Group to update diagnostic criteria IE. resulting 2023 Duke-ISCVID IE propose significant changes, including new microbiology diagnostics (enzyme immunoassay Bartonella species, polymerase chain...
Single-port or single-incision cholecystectomy with current rigid laparoscopic devices is limited by in-line visualization, restricting the ability to approach surgical site proper angles and instrumentation. A single-port access system articulating arms strong instrumentation should minimize these issues. The TransEnterix may facilitate safe straightforward surgery.The surgery was used in both survival nonsurvival porcine cholecystectomies under animal use committee approval. Nonsurvival...
Aortopulmonary collaterals (APC) have been associated with an increased risk of choreoathetosis after deep hypothermic circulatory arrest (DHCA). To study the effects APC on cerebral hemodynamics and metabolism before DHCA, a piglet model was developed.Protocol 1: Eight 4- to 6-week-old piglets underwent placement left subclavian-to-main pulmonary artery shunt. Control shunts (n = 4) were ligated, patent. All animals placed cardiopulmonary bypass (CPB) cooled in identical fashion for 20...
Cardiac haemangioma is an extremely rare, benign vascular tumour. A 42-year-old female patient who was previously very active presented with complaints of exertional chest pain as well lower extremity oedema. Computed tomography and magnetic resonance imaging showed a large mass in the anterior mediastinum originating from right atrioventricular groove abutting superior vena cava, atrium, ventricular outflow tract aortic root. Open biopsy via mini-thoracotomy revealed cavernous haemangioma....
Achieving transmural tissue ablation might be necessary for successful treatment of atrial fibrillation. The purpose this study was to evaluate the reproducibility left using a high-intensity focused ultrasound energy system in calf model.
Children with complete DiGeorge anomaly (cDGA) have congenital athymia, resulting in severe T cell immunodeficiency and susceptibility to a broad range of infections. We report the clinical course, immunologic phenotypes, treatment, outcomes three cases disseminated nontuberculous mycobacterial infections (NTM) patients cDGA who underwent cultured thymus tissue implantation (CTTI). Two were diagnosed Mycobacterium avium complex (MAC) one patient kansasii . All required protracted therapy...
This case demonstrates the use of QRS scoring to quantify myocardial scar in a patient with cardiac sarcoidosis and left bundle branch block who progressively received an implantable defibrillator, resynchronization therapy (CRT), ventricular assist device transplantation. has been shown correlate magnetic resonance imaging measurements scar, identify arrhythmogenic substrate predict response CRT, but had not previously compared pathology‐documented nonischemic cardiomyopathies. Further...
Osteosarcoma is a primary malignancy of bone. Current therapy includes neoadjuvant chemotherapy, surgery, and postoperative (adjuvant) chemotherapy. Prolonged treatment with chemotherapeutic agents may place patients at increased risk for complications including secondary malignancy. The authors have had promising results surgery alone in the osteosarcoma. This study retrospectively examines osteosarcoma bone no evidence distant metastases.Fifty-four patients, localized received followed by...
CD28:CD80/86 pathway costimulation blockade (CoB) with the CD80/86-specific fusion protein CTLA4-Ig prevents T cell-mediated allograft rejection in mice. However, humans, transplantation CoB has been hampered by resistant (CoBRR). CoBRR attributed part to pathogen-driven cell repertoire maturation and resultant heterologous alloreactive memory. This demonstrated experimentally prior murine models have used viral pathogens, regimens, graft types and/or antigen systems atypically encountered...