A5100856129- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Organ Donation and Transplantation
- Topic Modeling
- Natural Language Processing Techniques
- Cytomegalovirus and herpesvirus research
- Transplantation: Methods and Outcomes
- Organ and Tissue Transplantation Research
- Pharmacological Effects and Toxicity Studies
- Renal and Vascular Pathologies
- Toxoplasma gondii Research Studies
- Pleural and Pulmonary Diseases
- Lung Cancer Diagnosis and Treatment
- Genomics and Phylogenetic Studies
- Mycobacterium research and diagnosis
- Neurological Complications and Syndromes
- Multimodal Machine Learning Applications
- Systemic Lupus Erythematosus Research
- Natural product bioactivities and synthesis
- Pregnancy and Medication Impact
- Traditional Chinese Medicine Analysis
- Phytochemical Studies and Bioactivities
- Uterine Myomas and Treatments
- Polyomavirus and related diseases
- Digital and Cyber Forensics
Shenzhen University Health Science Center
2024-2025
First Affiliated Hospital of Henan University
2024
Wenzhou Medical University
2024
Fudan University
2023-2024
Nanjing Agricultural University
2024
Ministry of Agriculture and Rural Affairs
2024
Shanghai Artificial Intelligence Laboratory
2023
First Affiliated Hospital of Xi'an Jiaotong University
2010-2020
Xi'an Jiaotong University
2002-2015
Beijing Chao-Yang Hospital
2015
The evolution of Large Language Models (LLMs) like ChatGPT and GPT-4 has sparked discussions on the advent Artificial General Intelligence (AGI). However, replicating such advancements in open-source models been challenging. This paper introduces InternLM2, an LLM that outperforms its predecessors comprehensive evaluations across 6 dimensions 30 benchmarks, long-context modeling, open-ended subjective through innovative pre-training optimization techniques. process InternLM2 is meticulously...
Abstract Conversational large language models (LLMs) such as ChatGPT and GPT-4 have recently exhibited remarkable capabilities across various domains, capturing widespread attention from the public. To facilitate this line of research, in paper, we report development MOSS, an open-sourced conversational LLM that contains 16 B parameters can perform a variety instructions multi-turn interactions with humans. The base model MOSS is pre-trained on large-scale unlabeled English, Chinese, code...
Hemodynamic monitoring can reflect cardiac function and blood perfusion is an indispensable method in clinical practice. Invasive hemodynamic methods represented by the thermodilution are limited their application scope because they require vascular cannulation. Non-invasive has attracted extensive attention from medical companies clinicians at home abroad recent years due to its advantages such as safety, non-invasiveness, continuous monitoring, simple operation, low cost. This paper...
Jailbreak attacks are crucial for identifying and mitigating the security vulnerabilities of Large Language Models (LLMs). They designed to bypass safeguards elicit prohibited outputs. However, due significant differences among various jailbreak methods, there is no standard implementation framework available community, which limits comprehensive evaluations. This paper introduces EasyJailbreak, a unified simplifying construction evaluation against LLMs. It builds using four components:...
The cases of donation after brain death followed by circulatory (DBCD) and cardiac (DCD) have been increased year in China. Further research is needed to understand the outcomes risk factors delayed graft function (DGF) order minimize DGF ameliorate its potential impact on long-term outcomes. This study was explore differences between DBCD DCD transplant main for DBCD. Retrospective analysis clinical data 367donations citizens’ kidney procedures (donors recipients) July 2012 August 2015 at...
Abstract As a commonly used traditional Chinese medicine, Descurainia sophia has various reported pharmacological activities such as prevention of chronic diseases, cardiovascular protection, neuroprotection, anticancer, antioxidant, and high nutritional values, but its mitochondrial genome (mitogenome) not been reported. In this study, the D. mitogenome was sequenced, assembled annotated using next generation sequencing technologies on Illumina HiSeq PacBio Sequel platform. The results...
Abstract Bronchopleural fistula (BPF), a common complication of lobectomy, is pathological communication between the bronchus and pleural space. The bronchial stump (BSF), which located on stump, specific type BPF. BSF can be directly diagnosed via bronchoscopy. However, identification becomes difficult when very small (less than 1 mm), referred to as micro in this study because it cannot found during bronchoscopic exploration. This clinical dilemma easily leads misdiagnosis BSF. In paper,...
We compared the efficacy and safety of 2 different treatments CMV infection, including asymptomatic replication disease.852 renal transplantation recipients, disease, received antiviral therapies intravenous acyclovir or comprehensive anti-infection solution, mainly with ganciclovir. Effect, time, acute allograft rejection, were analyzed during therapyThe total effective rates higher ganciclovir in both (98.96% vs. 84.90%) disease (96.29% 50.36%). Ganciclovir significantly shortened therapy...
Acute rejection (AR) is a strong risk factor for chronic in renal transplant recipients. Accurate and timely diagnosis of AR episodes very important disease control prognosis. Therefore, objectively evaluated the immune status patients essential field post-transplantation treatment. This longitudinal study investigated usefulness five biomarkers, human leukocyte antigen (HLA)-G5 sCD30 level sera, intracellular adenosine triphosphate (iATP) release CD4(+) T cells, granzyme B/perforin...
Co-administration of diltiazem and cyclosporine A (CsA) in kidney transplant recipients shows improvement renal transplantation outcomes.We respectively analyzed 1531 treated by different immunosuppressive therapy schemes from 1986 to 2003. They were divided into three groups depending on their schemes: control group with a standard triple without use diltiazem; study I the combination but slightly low CsA; II modified lower CsA. The CsA blood concentrations, posttransplant complications,...
Background Due to the current high demand for transplant tissue, an increasing proportion of kidney donors are considered extended criteria donors, which results in a higher incidence delayed graft function (DGF) organ recipients. Therefore, it is important fully investigate risk factors DGF, and establish prediction system assess donor quality before transplantation.Methods A total 333 donation after cardiac death recipients were included this retrospective study. Both univariate...
Renal ischemia/reperfusion(I/R) is an important injury part of ischemic acute renal failure, and it also the main factor that affects early functional recovery long-term survival transplanted kidney in transplantation. In this study, we cloned expressed truncated Na+/K+-ATPase β(tNKAβ) demonstrated tNKAβ could activate NKA α subunit induce protective effect on human kidney-2(HK-2) cells via PKCɛ signal pathway. The half maximum effective concentrations (EC₅₀) were 0.24 µM. Furthermore,...
Kai Lv, Shuo Zhang, Tianle Gu, Shuhao Xing, Jiawei Hong, Keyu Chen, Xiaoran Liu, Yuqing Yang, Honglin Guo, Tengxiao Yu Sun, Qipeng Hang Yan, Xipeng Qiu. Proceedings of the 2023 Conference on Empirical Methods in Natural Language Processing: System Demonstrations. 2023.
The aim of this study was to evaluate the diagnostic value different detection methods for cytomegalovirus (CMV) infection after renal transplantation and also establish a system monitor therapy CMV infection.We retrospectively studied 1516 transplant recipients from June 1994 December 2006. All patients were screened CMV-DNA. A total 1402 had received CMV-IgG/IgM since 1996 660 antigen 2000.A 664 (43.8%) developed infection. sensitivity, specificity Youden index three methods, respectively,...
In the burgeoning field of large language models (LLMs), assessment fundamental knowledge remains a critical challenge, particularly for tailored to Chinese and culture. This paper introduces FoundaBench, pioneering benchmark designed rigorously evaluate capabilities LLMs. FoundaBench encompasses diverse array 3354 multiple-choice questions across common sense K-12 educational subjects, meticulously curated reflect breadth depth everyday academic knowledge. We present an extensive evaluation...
Abstract Objectives As a traditional Chinese medicine, Lepidium apetalum is commonly used for purging the lung, relieving dyspnea, alleviating edema, and has significant pharmacological effects on cardiovascular disease, hyperlipidemia, etc. In addition, seeds of L. are rich in unsaturated fatty acids, sterols, glucosinolates have variety biological activity compounds. To facilitate genomics, phylogenetic secondary metabolite biosynthesis studies , we assembled high-resolution genome . Data...
Large Language Models (LLMs) like GPT and LLaMA are revolutionizing the AI industry with their sophisticated capabilities. Training these models requires vast GPU clusters significant computing time, posing major challenges in terms of scalability, efficiency, reliability. This survey explores recent advancements training systems for LLMs, including innovations infrastructure accelerators, networking, storage, scheduling. Additionally, covers parallelism strategies, as well optimizations...