A5102833574- Electrospun Nanofibers in Biomedical Applications
- biodegradable polymer synthesis and properties
- CRISPR and Genetic Engineering
- Molecular Sensors and Ion Detection
- Advanced biosensing and bioanalysis techniques
- Advanced Sensor and Energy Harvesting Materials
- Rock Mechanics and Modeling
- Luminescence and Fluorescent Materials
- Gallbladder and Bile Duct Disorders
- Electrochemical sensors and biosensors
- Pediatric Hepatobiliary Diseases and Treatments
- Graphene and Nanomaterials Applications
- Electrohydrodynamics and Fluid Dynamics
- Seismic Imaging and Inversion Techniques
- Nanoparticle-Based Drug Delivery
- Sulfur Compounds in Biology
- Environmental remediation with nanomaterials
- Viral gastroenteritis research and epidemiology
- DNA and Nucleic Acid Chemistry
- Advanced Polymer Synthesis and Characterization
- Viral Infections and Immunology Research
- Hydrocarbon exploration and reservoir analysis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Metal and Thin Film Mechanics
- Carbon dioxide utilization in catalysis
Sericultural Research Institute
2024-2025
Jiangsu University of Science and Technology
2021-2025
Chinese Academy of Agricultural Sciences
2025
Ministry of Agriculture and Rural Affairs
2025
Shanghai Jiao Tong University
2021-2024
Communication University of China
2024
Institute of Rock and Soil Mechanics
2023
University of Shanghai for Science and Technology
2023
Chinese Academy of Sciences
2003-2021
University of Chinese Academy of Sciences
2005-2021
Abstract The poly(vinyl alcohol)/poly( N ‐vinyl pyrrolidone) (PVA–PVP) hydrogels containing silver nanoparticles were prepared by repeated freezing–thawing treatment. content in the solid composition was range of 0.1–1.0 wt %, particle size from 20 to 100 nm, and weight ratio PVA PVP 70 : 30. influence on properties PVA–PVP matrix investigated differential scanning calorimeter, infrared spectroscopy UV–vis spectroscopy, using films particles as a model. morphology freeze‐dried hydrogel...
Abstract Biodegradable poly( l ‐lactide) (PLLA) and poly(ε‐caprolactone) (PCL) were electrospun into ultrafine fibers. The technological parameters influencing the spinning process morphology of fibers obtained examined. These included solvent composition, addition certain organic salts, molecular weight concentration polymers, capillary diameter, air ventilation, pressure imposed on surface solution as well electrostatic field. By properly choosing adjusting these parameters, submicron PLLA...
A novel rhodamine-based highly sensitive and selective colorimetric off-on fluorescent chemosensor for Hg2+ ions is designed prepared by using the well-known thiospirolactam rhodamine chromophore furfural hydrazone as signal-reporting groups. The photophysical characterization Hg2+-binding properties of sensor RS1 in neutral N, N-dimethylformamide (DMF) aqueous solution are also investigated. signal change based on a specific metal ion induced reversible ring-opening mechanism spirolactam....
A novel naphthalimide-based fluorescent sensor bearing the N,N′-bis(salicylidene)diethylenetriamine receptor was developed, which exhibited dual signaling behaviors for Cd2+ and Cu2+, applicable to environmental biological milieus. Upon addition of Cd2+, fluorescence intensity enhanced in a linear fashion with maximum increase about 4-fold. Moreover, 1 1–Cd2+ complex, Cu2+ easily recognized by marked quenching. The selectivity sensitivity were satisfactory achieving detection limit at...
Coronavirus disease (COVID-19), caused by SARS-CoV-2 infection and its mutations, has spread rapidly all over the world still requires sensitive detection to distinguish mutations. CRISPR-based diagnosis been regarded as a next-generation method; however, it some limitations, such need for specific recognition sequences multiple enzymes multiplex detection. Therefore, research on exploration development of novel nucleases helps promote diagnoses. Prokaryotic Argonaute (Ago) proteins exert...
Abstract Poly(vinyl alcohol)/poly( N ‐vinyl pyrrolidone) (PVP)/chitosan hydrogels were prepared by a low‐temperature treatment and subsequent 60 Co γ‐ray irradiation then medicated with ciprofloxacin lactate (an antibiotic) chitosan oligomer (molecular weight = 3000 g/mol). The gel content, swelling ratio, tensile strength, crystallinity of the determined. effects molecular weight, procedure, radiation dosage on hydrogel properties examined. was lowered irradiation, but its basic...
A dual-mechanism intramolecular charge transfer (ICT)-FRET fluorescent probe for the selective detection of H2 O2 in living cells has been designed and synthesized. This used a coumarin-naphthalimide hybrid as FRET platform boronate moiety recognition group. Upon addition , exhibited redshifted (73 nm) fluorescence emission, ratio intensities at λ=558 485 nm (F558 /F485 ) shifted notably (up to 100-fold). Moreover, there was good linearity (R2 =0.9911) between concentration range 0 60 μm,...
Biodegradable poly(lactide-co-glycolide) (PLGA) antimicrobial nanofibers containing silver nanoparticles were prepared by electrospinning technique. Characterization of the Ag/PLGA nanofiber mats determined using SEM, TEM, WAXD and UV-vis spectrum. The antibacterial efficacy composites made PLGA fibers was measured. antimicroorganization Ag along with biodegradability can be combined in practical medical applications.
Ovarian cancer has been the most lethal gynaecological malignancy worldwide. Additionally, triptolide is an active substance that extracted from Chinese herbal medicine T. wilfordii Hook F. , which possesses anti-tumor, immunomodulatory and anti-inflammatory properties. In recent years, TP attracted increasing attention because of its broad-spectrum efficient anti-tumor activity. Nevertheless, clinical utility limited due to severe side effects. this study, we constructed...
Mesophilic Argonautes (Agos) from microbial resources have received significant attention due to their potential applications in genome editing and molecular diagnostics. This study characterizes a novel Ago Pseudobutyrivibrio ruminis (PrAgo), which can cleave single-stranded DNA using guide (gDNA). PrAgo, functioning as multi-turnover enzyme, effectively cleaves 5'-phosphate gDNA, 14-30 nucleotides length, the presence of both Mn
Abstract An ICT‐based mitochondria‐targeted fluorescent probe Mito‐NP was designed and synthesized for the detection of H 2 O , with radical fluorescence intensity changes (up to 120‐fold) a large Stokes shift (93 nm) in aqueous solution. There good linear relationship (R =0.9983) between concentration range 0 100 μM at 553 nm, low limit 0.25 (S/N=3). could also visualize enzymatically generated . Furthermore, detect endogenous mitochondria targeting ability living cells change levels during...
Abstract Paclitaxel‐loaded poly(ethylene glycol)‐ b ‐poly( l ‐lactide (LA)) (PEG‐PLA) micelles were prepared by two methods. One is physical encapsulation of paclitaxel in composed a PEG‐PLA block copolymer and the other based on PEG‐PLA–paclitaxel conjugate, abbreviated as “conjugate micelles”. Their physicochemical characteristics, e.g. critical micelle concentration (CMC), morphology, size distribution then evaluated means fluorescence spectroscopy, scanning electron microscopy (SEM),...