A5100569632- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Medical Imaging and Pathology Studies
- Tracheal and airway disorders
- Nanoplatforms for cancer theranostics
- Lung Cancer Diagnosis and Treatment
- Photodynamic Therapy Research Studies
- Lymphoma Diagnosis and Treatment
- Fungal Infections and Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Laser Applications in Dentistry and Medicine
- Pleural and Pulmonary Diseases
- Antifungal resistance and susceptibility
- Bone health and treatments
- Transplantation: Methods and Outcomes
- Cardiac tumors and thrombi
- Nail Diseases and Treatments
- Occupational and environmental lung diseases
- Tuberous Sclerosis Complex Research
- Pneumonia and Respiratory Infections
- Sarcoidosis and Beryllium Toxicity Research
- Gastrointestinal Tumor Research and Treatment
- Cancer, Hypoxia, and Metabolism
- Salivary Gland Tumors Diagnosis and Treatment
- Parathyroid Disorders and Treatments
- Anesthesia and Pain Management
Shandong First Medical University
2024-2025
Shandong Maternal and Child Health Hospital
2020-2025
Jinan Maternity And Care Hospital
2018-2025
Nanjing Drum Tower Hospital
2015-2024
Qingdao University of Science and Technology
2023
Zhangqiu City People's Hospital
2021
Nanjing University
2000-2015
Nanjing General Hospital of Nanjing Military Command
2014
MP Technologies (United States)
2008
Shanxi Science and Technology Department
2006
Background Accelerated biological ageing has been associated with an increased risk of several chronic respiratory diseases. However, the associations between phenotypic age, a new age indicator based on clinical chemistry biomarkers, and common diseases have not evaluated. Methods We analysed data from 308 592 participants at baseline in UK Biobank. The was calculated chronological nine including albumin, alkaline phosphatase, creatinine, glucose, C-reactive protein, lymphocyte percent,...
Epithelial-mesenchymal transition (EMT) is defined as switching of polarized epithelial cells to a migratory fibroblastoid phenotype. EMT known be involved in the progression and metastasis various cancers. The aim was evaluate that whether EMT-related proteins' alterations are associated with clinicopathological features prognosis lung adenocarcinoma.The expression proteins including cytokeratin, E-cadherin, TTF-1, β-catenin, vimentin, Snail, Twist, CD44 evaluated by immunohistochemistry...
// Yujie Zhang 1, 2, 3 , Jun Du Jianchao Zheng Jiaojing Liu 2 Rui Xu 4 Tian Shen Yichao Zhu Chang Hong Wang Zhihong 5 Fanqing Meng 6 Yan 7 Yongchang Chen 8 Yong 9 Luo Gu 1 Cancer Center, Nanjing Medical University, Nanjing, Jiangsu 210029, China Department of Biochemistry and Molecular Biology, Physiology, Biotechnology, Pathophysiology, the First Affiliated Hospital Drum Tower University School, 210008, Second 210011, School Science Laboratory Medicine, Zhenjiang, 212013, Correspondence to:...
Background: The placenta accreta spectrum (PAS) represents a significant risk factor for severe postpartum hemorrhage. Recent studies have demonstrated the safety of neuraxial anesthesia (NA) in cesarean delivery (CD) patients with PAS. Objectives: To evaluate peripartum hemorrhage PAS who underwent CD under NA. Design: A multicenter retrospective cohort study. Methods: This study analyzed 214 diagnosed Logistic regression was used to identify factors increasing total six machine learning...
Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive scarring disease with unknown etiology. The evidence of pathogenic role for transforming growth factor‐beta (TGF‐β) in the development progression IPF overwhelming. In present study, we investigated interleukin‐22 (IL‐22) pathogenesis by regulating TGF‐β pathway. We measured parameters tissue samples from clinical cohort IPF. IL‐22R knock out (IL‐22RA1 −/− ) IL‐22 supplementation mouse models were used to determine if...
Cryptogenic organizing pneumonia (COP) is characterized by good response to corticosteroids, but frequent relapses after reduction or cessation of treatment are noted. The incidence, risk factors relapse, and long-term outcomes patients with COP remain undetermined. Patients from September 2010 December 2017 were enrolled. Hospital office records used as data sources. Clinical information, lab examinations, chest radiographs, courses, follow-up collected. Relapse group was defined worsening...
Background: Pyruvate kinase isozyme type M2 (PKM2) is a key glycolytic enzyme and upregulated in multiple human malignancies. However, the role of PKM2 cervical cancer (CC) remains elusive. Thus, this study explored CC by detecting its expression patterns tissues cell lines investigated effects on proliferation invasion. Materials methods: Quantitative reverse transcription polymerase chain reaction (qRT-PCR), immunohistochemistry western blotting assays were used to detect cells. In vitro,...
Pulmonary sclerosing pneumocytoma (PSP) typically presents solitary and peripheral mass, while only rarely cases display unusual multiple lesions. We reported a extremely rare case of PSP with diffusely-scattered nodules in the right lung.Diffusely round-shaped nodular shadows lung were found by CT scan 31-year-old Chinese woman. The patient undergone pneumnectomy. Grossly, numerous small nodules, up to 2.5 cm greatest dimension identified upper, middle lower lobes lung. Histologically,...
Backgrounds Growth differentiation factor 15 (GDF-15) is a highly divergent member of the TGF-β superfamily and has been implicated in various biological functions. However, expression GDF-15 patients with acute exacerbation idiopathic pulmonary fibrosis (AE-IPF) unclear. Method The study included 47 AE-IPF patients, 61 stable IPF (S-IPF) subjects, 31 healthy controls (HCs). Serum levels their lung were measured. correlation between serum other clinical parameters risk factors for AE...
Acute fibrinous and organizing pneumonia (AFOP) is a unique pathological entity with intra-alveolar fibrin in the form of "fibrin balls" pneumonia. It was divided into rare idiopathic interstitial according to classification notified by American Thoracic Society/European Respiratory Society 2013. As entity, it still not well known recognized clinicians. We reviewed clinical features 20 patients AFOP diagnosed teaching hospital.The medical records biopsy-proven diagnosis were retrospectively...
The present study aimed to investigate the clinicopathological features of primary intravascular large B-cell lymphoma (IVLBCL) lung. clinical and histopathological data three patients, literature was reviewed. Ethics Committees Drum Tower Hospital approved current based on cases. Fever respiratory symptoms were main presenting symptoms. Serum lactate dehydrogenase C‑reactive protein significantly increased. Diffuse ground glass opacities or nodular consolidations seen high resolution...
The development of local anesthetic (LA) system is the application commercial drug for pain management that indorses reversible obstructive mechanism neural transmission through preventing innervation process in human peripheral nerves. Ropivacaine (RV) one greatest frequently used LA s with actions long-lasting and low-toxicity post-operative management. In this work, we have approached novel design glycosylated chitosan (GCS) encapsulated mesoporous silica nanoparticles (GCS-MONPs)-based...