- Phytochemicals and Antioxidant Activities
- Acute Ischemic Stroke Management
- Cytokine Signaling Pathways and Interactions
- Electrolyte and hormonal disorders
- Remote Sensing and Land Use
- Rheumatoid Arthritis Research and Therapies
- Retinoids in leukemia and cellular processes
- Healthcare cost, quality, practices
- Renal function and acid-base balance
- Cancer, Stress, Anesthesia, and Immune Response
- Eosinophilic Disorders and Syndromes
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Medicinal Plants and Neuroprotection
- Metabolomics and Mass Spectrometry Studies
- Gut microbiota and health
- Glycosylation and Glycoproteins Research
- Crystal structures of chemical compounds
- Curcumin's Biomedical Applications
- Plant-derived Lignans Synthesis and Bioactivity
- Systemic Lupus Erythematosus Research
- Heavy Metals in Plants
- Phytochemistry and Biological Activities
- Antimicrobial Peptides and Activities
- Effects and risks of endocrine disrupting chemicals
- Cell Adhesion Molecules Research
Affiliated Zhongshan Hospital of Dalian University
2022-2024
Chengdu Second People's Hospital
2024
Seventh People's Hospital of Dalian
2023
Air Force Medical University
2017
The 309th Hospital of Chinese People's Liberation Army
2017
Shanghai University of Traditional Chinese Medicine
2015
Liaoning University of Traditional Chinese Medicine
2011-2013
Curcumin, a principle bioactive component of Curcuma longa L, is well known for its anti-hyperlipidemia effect. However, no holistic metabolic information curcumin on hyperlipidemia models has been revealed, which may provide us an insight into the underlying mechanism. In present work, NMR and MS based metabolomics was conducted to investigate intervention effect mice induced by high-fat diet (HFD) feeding 12 weeks. The HFD animals were orally administered with (40, 80 mg/kg) or lovastatin...
Introduction: Rheumatoid arthritis (RA) is an inflammatory immune-mediated disease that involves synovitis, cartilage destruction, and even joint damage. Traditional agents used for RA therapy remain unsatisfactory because of their low efficiency obvious adverse effects. Therefore, we here established microenvironment-responsive targeted micelles can respond to the increase in reactive oxygen species (ROS) levels improve macrophage-specific targeting loaded drugs. Methods: We prepared...
PM 2.5 is an important environmental problem threatening human health at present, which poses serious harm to body after inhalation. J. cannabifolia a traditional Chinese medicine exhibits anti-inflammatory effect. This study aimed investigate the inhibitory effect of main phenolic acid components on inflammation caused by . Effect cell activity and apoptosis were determined MTT, flow cytometry calcein AM/PI staining. PHBA, PHPAA, mixture PHBA PHPAA different concentrations given RAW264.7...
To test whether the internal transcribed spacer 2 (ITS2) region is an effective marker for using in authenticating of <em>Schisandra chinensis</em> at species and population levels, separately. And results showed that wild populations had higher percentage individuals substitution C→A site 86-bp than cultivated populations. At sites 10-bp, 37-bp, 42-bp 235-bp, these bases sphenanthera</em> samples differed from <em>S. chinensis</em>. Two levels inter-specific...
The molecule of the title compound, C(9)H(6)N(2)O(2), is almost planar, with a dihedral angle 3.0 (9)° between pyridine and benzene rings.
Background Bisphenol A (BPA), a characteristic endocrine disruptor, is substance that seriously interferes with the human system and causes reproductive disorders developmental abnormalities. However, its toxic effects on gut-liver-hormone axis are still unclear. Method Male female rats were exposed to BPA (300 mg/kg) by oral gavage for 60 consecutive days. H&amp;E staining was used histopathological evaluation, serum biochemical indexes determined using an automatic analyzer. The 16S...
To identify novel metabolic biomarkers for patients with acute ischemic stroke (AIS).
Background: Calponin 2 is involved in many types of malignancies, and it has been recognized as a regulator macrophage motility phagocytosis. We investigated whether could represents functional link between the inflammation cancer. Methods: 2−/− mice C57BL/6 wild type littermate controls were intraperitoneally injected with azoxymethane (AOM) followed by three cycles 2.5% dextran sulfate sodium (DSS) drinking water to induce colitis associated cancer (CAC). Acute chronic triggered DSS....