A5045167784- Dielectric materials and actuators
- High voltage insulation and dielectric phenomena
- Tuberculosis Research and Epidemiology
- Advanced Sensor and Energy Harvesting Materials
- Energy, Environment, Economic Growth
- Health Systems, Economic Evaluations, Quality of Life
- Oral microbiology and periodontitis research
- MicroRNA in disease regulation
- Infective Endocarditis Diagnosis and Management
- Circular RNAs in diseases
- Healthcare Systems and Reforms
- Vestibular and auditory disorders
- Climate Change Policy and Economics
- Frailty in Older Adults
- RNA Interference and Gene Delivery
- Pharmaceutical Economics and Policy
- Solar Thermal and Photovoltaic Systems
- Sustainable Supply Chain Management
- Environmental Sustainability in Business
- Renal cell carcinoma treatment
- Phase Change Materials Research
- RNA and protein synthesis mechanisms
- Economic and Financial Impacts of Cancer
- RNA Research and Splicing
- Liver Disease Diagnosis and Treatment
Zhejiang University
2023-2025
First Affiliated Hospital Zhejiang University
2023-2025
Nanjing Medical University
2023-2024
Tianjin University
2020-2024
Guangzhou University
2024
Shanghai Tenth People's Hospital
2024
Tongji University
2024
Sichuan University
2024
Shandong University of Science and Technology
2023
Universiti Putra Malaysia
2022-2023
Abstract The degradation of dielectric properties polypropylene (PP) at high temperature affects the operational stability metallised film capacitors. This study presents a method to improve high‐temperature performance PP through long‐chain branching modification and regulating crystalline properties. Different amounts nucleating agents were added branched (LCBPP) effect crystallisation on electrical results show that branches thermal by enhancing chain entanglement, also increase number...
Metalenses are expected to play an increasingly important role in miniaturized and integrated optical imaging components/systems. However, devising broadband achromatic metalenses with high focusing efficiencies is still quite challenging. In this work, we proposed aperture-shared partition phase cooperative manipulation approach for designing a high-efficiency metalens composed of two concentric sub-metalenses. As proof-of-concept, polarization-independent successfully designed the visible...
At high temperatures, the insulation performance of polypropylene (PP) decreases, making it challenging to meet application requirements metallized film capacitors. In this paper, dielectric PP is improved by long-chain branching modification and adding different kinds nucleating agents. The added agents are organic phosphate agent (NA-21), sorbitol (DMDBS), rare earth (WBG-Ⅱ) acylamino (TMB-5). results show that branches promote heterogeneous nucleation inhibit motion molecular chains,...
In this paper, a modification method based on gamma (γ)-ray irradiation and applied to polypropylene (PP) films is proposed enhance the dielectric properties for high-voltage direct current (HVDC) capacitors. With addition of 0.2 wt% trimethylolpropane triacrylate (TMPTA), PP are irradiated at doses 0, 2, 5 10 kGy. The sensitizer contributed improving crosslinking density under appropriate dose gel content can reach 22.54%. Experimental results show that loss conductivity decreased...
In line with the Sustainable Development Goals (SDGs) proposed by United Nations and general direction of global green low-carbon transformation, China has formulated a dual-carbon target. It aims to peak carbon dioxide emissions 2030 strive for neutrality 2060. Therefore, emission intensity (CEI) gradually become research focus. This study investigates effect ESG performance on CEI, explores moderating climate policy uncertainty (CPU) digital economy (DE) CEI. Provincial-level data in from...
The ocean plays a pivotal role as carbon sink, with microbial processes, particularly the pump, facilitating transformation of dissolved organic (DOC) into recalcitrant forms that support long-term sequestration. This study explores effects nutrient enrichment on DOC utilization and community dynamics through microcosm incubation experiment using incubated inert waters. We found addition, especially in T-4X treatment group where nutrients were added to reach four times ambient...
Abstract Head and neck squamous cell carcinoma (HNSCC) is a malignancy with poor prognosis chemotherapy resistance. Here, protein arginine methyltransferase 1 (PRMT1) identified as key driver of carboplatin (CBP) resistance in HNSCC. Analyses clinical samples, lines, patient‐derived organoids, xenograft models reveal that PRMT1 promotes tumor growth CBP through novel, methyltransferase‐independent mechanism. Conditional knockout suppresses tumorigenesis enhances sensitivity vivo,...
In this article, aiming at the high conductance loss and low breakdown strength of polypropylene (PP) film under a high-temperature environment, we attempt to improve dielectric properties PP films by blending cyclic olefin copolymer (COC). It is shown that these two materials have good interfacial compatibility. COC has little effect on crystal form PP/COC because it an amorphous polymer without polar group. At 105 °C, proportion beneficial decrease dc conductivity increase strength. Since...
Abstract Background In September 2019, the “4 + 7” centralized procurement pilot program was expanded nationwide aiming at reducing drug prices by means of volume-based and using accredited generic drugs for branded substitutes. Given current uncertain effect policy outside areas, this study conducted to evaluate impact National Volume-based Procurement on use policy-related after expansion. Method A single-group interrupted time series applied purchase data, covering 25 months from December...
Abstract Background In many areas of China, over 30% tuberculosis cases occur among the elderly. We aimed to investigate spatial distribution and environmental factors that predicted occurence in this group. Methods Data were collected on notified pulmonary (PTB) aged ≥ 65 years Zhejiang Province from 2010 2021. performed autocorrelation spatial-temporal scan statistics determine clusters epidemics. Spatial Durbin Model (SDM) analysis was used identify significant their spillover effects....
The graphite//5,7,12,14-pentacenetetrone organic dual-ion batteries display two well-defined discharge plateaus at 2.4 and 1.8 V, a high capacity retention of 92.2% after 100 cycles.
Previous observations have implicated miR-509-3p's ability in regulating cisplatin-triggered apoptosis ovarian cancer. However, the underlying mechanisms were not fully understood.The roles of miR-509-3p cellular assessed through MTT and DAPI assays. The confirmation regulation BCL2 family members by was investigated luciferase reporter assay, western blot, quantitative real-time PCR rescue experiments.MiR-509-3p can decrease IC50 values cisplatin promote cancer cells. Furthermore, on a...
Aims: XIAP is upregulated in chemoresistant epithelial ovarian cancer (EOC). However, the molecular mechanism of this dysregulation remains unclear. Materials & methods: The regulation by miR-509-3p was investigated luciferase reporter assay, real-time PCR and immunobloting, roles cellular proliferation apoptosis were accessed through MTT DAPI assays. Results: miR-509-3p, a downregulated miRNA EOC, can directly target via its 3′UTR. Overexpression not only downregulate expression cells but...
Abstract Objectives The public health system faces major challenges due to the double burden of diabetes mellitus (DM) and tuberculosis (TB) in China. We aimed investigate prevalence impact on patients with TB. Methods Stratified cluster sampling was used select 13 counties as study sites Zhejiang province. Patients who visited designated TB hospitals these areas participated this between 1 January 2017 28 February 2019. Multiple logistic regression models were performed association DM...
Mammalian cardiac troponin I (cTnI) contains a highly conserved amino-terminal extension harboring protein kinase A targets [serine-23 and -24 (Ser 23/24 )] that are phosphorylated during β-adrenergic stimulation to defend diastolic filling by means of an increased cardiomyocyte relaxation rate. In this work, we show the Ser -encoding exon 3 TNNI3 was pseudoexonized multiple times in shrews moles mimic phosphorylation without adrenergic stimulation, facilitating evolution exceptionally high...
Despite extensive investigation into the role of let-7 miRNAs in pathological tumor processes, their involvement DNA damage response remains unclear. Here we show that most family members down-regulate MDM4 expression via binding to mRNA at a conserved sequence. Expression exogenous miRNA mimics decreased protein but not levels. Several reagents increased expression, thereby decreasing levels glioma cells. Inhibition endogenous with antisense RNAs rescued or without MG132,...
Abstract Background The emergence of proprotein convertase subtilisin/kexin type 9 inhibitors offered dyslipidemia patients an alternative to statins for lipid‐lowering treatment. Understanding patient and physician preferences drugs may promote shared decision‐making improve treatment outcomes. Methods This study utilized online discrete choice experiment (DCE) assess the relative importance (RI) six attributes related drugs, including frequency administration, mode reduction low‐density...