A5027857357- Industrial Technology and Control Systems
- Hydraulic and Pneumatic Systems
- Lattice Boltzmann Simulation Studies
- Aerosol Filtration and Electrostatic Precipitation
- Advanced MEMS and NEMS Technologies
- Traffic Prediction and Management Techniques
- Topology Optimization in Engineering
- Control Systems in Engineering
- Advanced Fiber Optic Sensors
- Asphalt Pavement Performance Evaluation
- Traffic control and management
- Simulation and Modeling Applications
- Structural Health Monitoring Techniques
- Advanced Algorithms and Applications
- Advanced Optical Imaging Technologies
- Elevator Systems and Control
- Mechanical Engineering and Vibrations Research
- Advanced Sensor and Control Systems
- Fluid Dynamics and Vibration Analysis
- Mechanical and Optical Resonators
- Structural Engineering and Vibration Analysis
- Drilling and Well Engineering
- Aerodynamics and Fluid Dynamics Research
- Acoustic Wave Resonator Technologies
- Engineering Applied Research
University of Science and Technology of China
2025
Tongji University
2015-2024
Jiangsu University
2020-2023
Anhui University
2022-2023
Beijing Chaoyang Emergency Medical Center
2023
Capital Medical University
2023
University of Nebraska Medical Center
2022
China Pharmaceutical University
2017
Clemson University
2015
Chinese Academy of Sciences
2014
Immunosuppressive phenotype compromised immunotherapy efficacy of hepatocellular carcinoma. Tumor cells intrinsic mitochondria dynamics could pass effects on the extracellular microenvironment through mtDNA stress. PGAM5 anchors at and regulates functions. We aim to explore whether regulation tumor-intrinsic affects tumor-infiltrating immune in can be a therapeutic target enhance carcinoma (HCC). analyzed correlation expression infiltration using Gene Expression Omnibus (GEO) The Cancer...
Thermosensitive hydrogels have increasingly received considerable attention for local drug delivery based on many advantages. However, burst release of drugs is becoming a critical challenge when the are employed. Microspheres- (MS-) loaded thermosensitive were thus fabricated to address this limitation. Employing an orthogonal design, spray-dried operations tenofovir (TFV)/Bletilla striata polysaccharide (BSP)/chitosan (CTS) MS optimized according loading (DL). The physicochemical...
Highland barley is a well-known cereal in Qinghai-Tibet Plateau area with high nutritional value, which has been reported to be health-promoting grain for the obesity and diabetes. Fermentation by certain microbiota can improve flavor property characteristics. In present study, Lactiplantibacillus plantarum Saccharomyces cerevisiae were singly or jointly applied ferment highland barley, profile of volatile substances lipid-lowering effects respective extracts analyzed. Results indicated that...
A lattice Boltzmann method for natural convection with multicomponent and multiphase fluids in a two‐dimensional square cavity is presented. The model combines passive‐scalar approach, which extended to be available immiscible flow this paper. It has good computational efficiency. of two the same are simulated using model, agreement literature data satisfactory. case study bubble different presented show heat transfer convection. also reflects potential present simulating thermal Rayleigh numbers.
This paper aims at the problem of intersection traffic oversaturation and spillover queuing vehicles caused by random fluctuations flow. A self-organizing control model with road capacity constraints taking minimum expected flow delay as goal is established to realize real-time adaptive signal phase duration. Taking local its adjacent intersections basic unit control, defining space in state equations are established. According equations, an online method for solving optimal duration...
A double-enzyme-catalyzed strategy for the synthesis of enantiocomplementary vicinal fluoro alcohols through a one-pot, three-step process including lipase-catalyzed hydrolysis, spontaneous decarboxylative fluorination, and subsequent ketoreductase-catalyzed reduction was developed. With this approach, β-ketonic esters were converted to corresponding with high isolated yields (up 92%) stereoselectivities 99%). This new cascade addresses some issues in comparison traditional methods such as...
Pancreatic cancer (PC) is a fatal human cancer, whose progression highly dependent on the nervous tumor microenvironment. In present study, cationic perfluorocarbon nanoemulsions were employed as an intraperitoneal delivery platform to facilitate and penetration of therapeutic small interfering RNA (siRNA) orthotopic pancreatic tumors. The nanoemulsion was used silence expression nerve growth factor (NGF) way favorably modulating tumor–neuronal interactions in exhibited deep that exocytosis...
As the number of wire circuits used in automobiles increases, larger force is required to mate connectors. In order reduce assembling cost, connectors with low insertion are desired. This may, however, result fretting problems electric contacts terminals. To understand mechanism this failure, computational modeling believed be beneficial. The authors have developed a model based on cellular automata simulate contact failure. One difficulties models evaluate breakage oxidized particles...
In this paper, two-phase fluid mixture flow in rectangular two-inlet cavity is studied using lattice Boltzmann method (LBM). To simulate fluids with large viscosity difference, the pseudo-potential model improved. The improved verified for surface tension through Laplace's law and shown much better performance simulating difference than model. multiple-relaxation-time (MRT) scheme used to enhance numerical stability. Then same different simulated by present (LB) model, LB volume-of-fluid...
Dysregulation of Hedgehog (Hh) signaling pathway is one the hallmarks pancreatic ductal adenocarcinoma (PDA). Lithium, a clinical mood stabilizer for treatment mental disorders, known to suppress tumorigenic potential PDA cells by targeting Hh/Gli pathway. In this study, we investigated molecular mechanism lithium induced down-regulation Hh/Gli1. Our data show that promotes poly-ubiquitination and proteasome-mediated degradation Gli1 through activating E3 ligase ITCH. Additionally, enhances...
Funding institutions and researchers increasingly expect that data will be shared to increase scientific integrity provide other scientists with the opportunity use novel methods may advance understanding in a particular field of study. In practice, sharing human subject can complicated because must de-identified prior sharing. Moreover, integrating varied types collected study challenging time consuming. For example, from structural imaging studies complex disorder requires integration...
Elaborate the unprecedented market opportunities of foamed asphalt technology combining national condition, analyze urgency development foaming functional module, and be first one in china to bring up an idea that adding module mixing plant order achieve cold in-plant recycling technique with new material as stabilizer. Successfully develop based on modular, verify its application through experiment asphalt. The can change passive situation due dependent foreign imports equipments, which...
To provide better reconstruction quality, it takes more time for iterative algorithms, especially when multiple holograms need to be computed. A non-iterative method calculating a phase hologram with adaptive weighted constraints is proposed, which iteratively calculates the optimized rectangular aperture as amplitude and multiplies initial quadratic complex amplitude. Subtraction feedback introduced improve visual effect avoid overcompensation problem of division feedback. The proposed...
Saponins from bitter melon (BMS) exert potential bioactivities and pharmacological activities, including anti-oxidation lifespan extension. However, the exact mechanisms of BMS in response to oxidative stress remain unknown. Results demonstrated that saponins could strengthen locomotive activities (body bend head thrashing) accompanied by delaying muscle fiber damage with age Caenorhabditis elegans. In addition, inhibited ROS accumulation, improved antioxidant enzymes like SOD (by 57.90%...
A novel tetranuclear Cu( ii ) complex was successfully synthesized, which could bind to DNA through an intercalative mode and cleave the leading cell death.
A multiple-image encryption method based on a computer-generated phase-only hologram (POH) algorithm and chaotic systems is proposed. In the proposed method, first, modified Gerchberg–Saxton (GS) applied to transform into corresponding sub-sampled POHs. Then, multiple POHs are combined using spatial division multiplexing (SDM). The then mapped digital image, each pixel of image transformed by system improve security form final ciphertext. GS employed generate POH, which prerequisite for SDM....