A5100708205- Plant Stress Responses and Tolerance
- Photosynthetic Processes and Mechanisms
- Plant Reproductive Biology
- Plant tissue culture and regeneration
- 3D Printing in Biomedical Research
- Advanced biosensing and bioanalysis techniques
- Plant Molecular Biology Research
- Chromosomal and Genetic Variations
- Genomics, phytochemicals, and oxidative stress
- Connective tissue disorders research
- Mitochondrial Function and Pathology
- CRISPR and Genetic Engineering
- MicroRNA in disease regulation
- Synthesis and bioactivity of alkaloids
- Cell death mechanisms and regulation
- Immune cells in cancer
- Paraoxonase enzyme and polymorphisms
- Molecular Sensors and Ion Detection
- Advanced Photocatalysis Techniques
- Antenna Design and Optimization
- Scoliosis diagnosis and treatment
- Congenital heart defects research
- Game Theory and Applications
- Experimental Behavioral Economics Studies
- Genetic Mapping and Diversity in Plants and Animals
Tianjin Medical University Cancer Institute and Hospital
2017-2025
Tianjin Normal University
2025
Chinese University of Hong Kong
2019-2024
National Kaohsiung University of Science and Technology
2024
Tianjin Medical University
2023-2024
National University of Singapore
2006-2023
China Agricultural University
2019-2023
Yunnan University
2023
Shenzhen Institute of Information Technology
2023
Shanghai Tenth People's Hospital
2023
Doubled haploid (DH) technology is used to obtain homozygous lines in a single generation, technique that significantly accelerates the crop breeding trajectory. Traditionally, vitro culture generate DHs, but this limited by species and genotype recalcitrance. In vivo induction (HI) through seed widely efficiently maize was recently extended several other crops. Here we show HI can be triggered mutation of DMP maternal inducer genes allopolyploid (allotetraploid) Brassica napus Nicotiana...
Bone marrow-derived mesenchymal stem cell (MSC) is one of the most actively studied types due to its regenerative potential and immunomodulatory properties. Conventional expansion methods using 2D tissue culture plates 2.5D microcarriers in bioreactors can generate large numbers, but they compromise potency lack mechanical preconditioning prepare MSC for physiological loading expected
Abstract FUN14 domain containing 1 (FUNDC1) is an important molecule in receptor‐dependent mitophagy. However, the roles of FUNDC1 human cancer biology remain unknown. The aim this study was to explore expression and cervical cancer. Immunohistochemistry Western blotting were applied detect FUNDC1, small‐hairpin RNA inhibit endogenous cells. MTT assays Flow cytometric analysis examine cell proliferation apoptosis. Immunofluorescence used formation γH2AX foci evaluate extent DNA damage....
The application of hydrogels in bone repair is limited due to their low mechanical strength. Simulating extracellular matrix, methylacrylylated gelatin (GelMA)/methylacrylylated hyaluronic acid (HAMA)/nano-hydroxyapatite(nHap) composite were prepared by combining the double network strategy and nHap this study. precursor solutions injectable shear thinning property. compressive elastic modulus hydrogel was significantly enhanced, fracture strength nearly reached 1 MPa, retained its high...
Contrast-induced acute kidney injury (CI-AKI) has become the third leading cause of hospital-acquired injury. A comprehensive analysis current state research in field CI-AKI will help to reveal trends and hot topics field. To date, there are no published bibliometric analyses related studies. Here, we analyze relevant literature since emergence concept provide valuable insights. The was collected from Web Science Core Collection. data were analyzed visually using CiteSpace VOSviewer...
This study focuses on investigating concrete's engineering properties when sugarcane bagasse ash (SCBA) is used as a partial substitute for cement. SCBA obtained by sintering at 700°C one hour. The research analyzes various of concrete different water-cement ratios (0.3, 0.4, 0.5) and curing periods (7, 28, 56, 91 days), including fresh-mixed (slump, flow, unit weight, setting time), characteristics (compressive, splitting strength, pozzolanic index, ultrasonic pulse velocity (UPV),...
Immunosuppressive phenotype compromised immunotherapy efficacy of hepatocellular carcinoma. Tumor cells intrinsic mitochondria dynamics could pass effects on the extracellular microenvironment through mtDNA stress. PGAM5 anchors at and regulates functions. We aim to explore whether regulation tumor-intrinsic affects tumor-infiltrating immune in can be a therapeutic target enhance carcinoma (HCC). analyzed correlation expression infiltration using Gene Expression Omnibus (GEO) The Cancer...
Abstract Hepatocellular carcinoma (HCC) is the one of most common and deadly cancers, also highly resistant to conventional chemotherapy treatments. Mitochondrial phosphoglycerate mutase/protein phosphatase (PGAM5) regulates mitochondrial homeostasis cell death, however, little known about its roles in cancer. The aim this study was explore clinical significance potential biological functions PGAM5 hepatocellular carcinoma. For first time, our results show that significantly upregulated HCC...
// Jing Wang 1, * , Fanlin Meng EnYu Dai 1 Feng Yang Shuyuan Xiaowen Chen Lei Yuwen 2 Wei Jiang College of Bioinformatics Science and Technology, Harbin Medical University, 150081, P. R. China The 2nd Affiliated Hospital, These authors have contributed equally to this work Correspondence to: Jiang, email: jiangwei@hrbmu.edu.cn Keywords: small molecule, miRNA, drug, functional similarity, microarray Received: November 26, 2015 Accepted: May 08, 2016 Published: 24, ABSTRACT MicroRNAs (miRNAs)...
Matrine has been reported to be an effective anti‑tumor therapy; however, the anti-metastatic effects of matrine on hepatocellular carcinoma (HCC) and molecular mechanism(s) involved remain unclear. Therefore, aims present study were evaluate hepatoma determine associated involved. In study, was confirmed prevent proliferation HCC cells it observed that also inhibited migratory, invasive capabilities at non‑toxic concentrations. Additionally, increased epithelial‑cadherin expression...
Abstract The pharmacokinetic disposition of a dietary cancer chemopreventive compound dibenzoylmethane (DBM) was studied in male Sprague‐Dawley rats after intravenous (i.v.) and oral (p.o.) administrations. Following single i.v. bolus dose, the mean plasma clearance ( CL ) DBM low compared with hepatic blood flow. displayed high volume distribution V ss). elimination terminal t 1/2 long. , ss AUC 0−∞ /dose were similar between 10 mg/kg doses. After doses (10, 50 250 mg/kg), absolute...
Aims: Hydrogen sulfide (H2S) inhibits the proliferation of vascular smooth muscle cells (VSMCs). However, how cystathionine-gamma-lyase (CSE), a major enzyme that produces H2S, is regulated remains unknown. Whether calcium-sensing receptor (CaSR) VSMCs by regulating endogenous CSE/H2S pathway in diabetic rat has not been previously investigated. Methods and Results: The morphological ultrastructure alterations were tested transmission electron microscopy, changes H2S concentration relaxation...