A5103095380- Neuroblastoma Research and Treatments
- Sperm and Testicular Function
- Biomedical Research and Pathophysiology
- Aquatic Ecosystems and Phytoplankton Dynamics
- Epigenetics and DNA Methylation
- Autophagy in Disease and Therapy
- Retinoids in leukemia and cellular processes
- Assisted Reproductive Technology and Twin Pregnancy
- Alzheimer's disease research and treatments
- Microplastics and Plastic Pollution
- RNA modifications and cancer
- Collaborative Teaching and Inclusion
- Neurological Disorders and Treatments
- Extracellular vesicles in disease
- Neurological Disease Mechanisms and Treatments
- Geochemistry and Elemental Analysis
- Nitrogen and Sulfur Effects on Brassica
- Reproductive System and Pregnancy
- Global Educational Reforms and Inequalities
- Reproductive Biology and Fertility
- Parental Involvement in Education
- Glioma Diagnosis and Treatment
- Hedgehog Signaling Pathway Studies
- Mesenchymal stem cell research
- Renal and related cancers
Ningbo University
2024
Nanjing University
2020-2024
University of Chinese Academy of Sciences
2024
Institute of Geochemistry
2024
Chinese Academy of Sciences
2024
Sun Yat-sen Memorial Hospital
2023-2024
Sun Yat-sen University
2023-2024
Nanjing Medical University
2024
Macau University of Science and Technology
2023
Central China Normal University
2006
Nanoplastics (NPs), regarded as the emerging contaminants, can enter and be mostly accumulated in digest tract, which pose potential threat to intestinal health. In this study, mice were orally exposed polystyrene (PS), PS-COOH PS-NH2 NPs with size of ∼100 nm at a human equivalent dose for 28 consecutive days. All three kinds PS-NPs triggered Crohn's ileitis-like features, such ileum structure impairment, increased proinflammatory cytokines epithelial cell (IEC) necroptosis, PS-COOH/PS-NH2...
Background: Since primary prostate cancer (PCa) can advance to the life-threatening metastatic PCa, exploring molecular mechanisms underlying PCa metastasis is crucial for developing novel targeted preventive strategies decreasing mortality of PCa.RNA N 6 -methyladenosine (m A) an emerging regulatory mechanism gene expression and its specific roles in progression remains elusive.Methods: Western blotting, quantitative real-time PCR immunohistochemical analyses were used detect target cells...
Neuroblastoma (NB), the most common extracranial solid tumor in childhood, significantly contributes to cancer-related mortality, presenting a dearth of efficacious treatment strategies. Previously, our studies have substantiated potent cytotoxicity arsenic trioxide (ATO) against NB cells, however, specific underlying mechanism remains elusive. Here, we first identified ATO as novel GPX4 inhibitor, which could trigger ferroptosis cells. In vitro, inhibited proliferation and migration ability...
Leukocyte cell-derived chemotaxin 2 (LECT2) is linked to various immune diseases. Previously, we reported that serum LECT2 levels correlate with disease severity in atopic dermatitis (AD) patients. To investigate the role of AD and elucidate its potential mechanisms, used treat an mouse model induced by 1-Chloro-2,4-dinitrobenzene (DNCB) knockout (KO) wild-type (WT) mice, cell using TNF-α/IFN-γ-induced HaCaT cells. Inflammatory factors barrier proteins were analyzed histology,...
Phosphorites (P2O5 content > 18 wt%) are widespread in the world; however, high-quality phosphorite 30 is exceptionally rare. In South China, Devonian Shifang deposit represents not only a phosphorus ore resource but also hosts abundant rare earth elements (up to 3677.6 ppm). Despite its significance, provenance of this unique has remained unclear. study, we conducted U-Pb dating, Hf isotope, and trace element concentrations analysis detrital zircon from well constrain specific potential...
Dermatological adverse events (AEs) are generally mild during therapy with Bruton’s tyrosine kinase inhibitor (BTKi), and it is often unnecessary to adjust the BTKi dosage or discontinue treatment. However, in this study, we present cases of two patients diagnosed chronic lymphocytic leukemia/small lymphoma (CLL/SLL) who experienced severe dermatological AEs treatment subsequently had it. The first patient, previously suffered from rashes, rashes again along fever when exposed BTKi....
Neuroblastoma (NB) remains associated with a low overall survival rate over the long term. Abnormal activation of Hedgehog (HH) signaling pathway can activate transcription various downstream target genes that promote NB. Both arsenic trioxide (ATO) and itraconazole (ITRA) inhibit tumor growth. To determine whether ATO combined ITRA be used to treat NB HH activation, we examined effects monotherapy or inhibition in Analysis CCK8 flow cytometry showed cell cycle, respectively. Real-time PCR...
As an emerging industry, the E-Sports industry has been booming in 21st century. With more and games tournaments coming up, entered views of people. In China, not only gained attention love but also some people have taken up related jobs, especially younger generation. This paper focuses on impact that Chinese society is based development worldwide within terms cultural, economic employment dimensions. To achieve this goal, uses literature analysis, data analysis case studies. It possible to...