A5003897652- Nanoplatforms for cancer theranostics
- Advanced Nanomaterials in Catalysis
- PARP inhibition in cancer therapy
- Advanced biosensing and bioanalysis techniques
- Radiation Therapy and Dosimetry
- DNA Repair Mechanisms
- Folate and B Vitamins Research
- Electromagnetic Launch and Propulsion Technology
- Esophageal and GI Pathology
- Cancer, Hypoxia, and Metabolism
- Cell death mechanisms and regulation
- Liver Disease Diagnosis and Treatment
- Magnetic Field Sensors Techniques
- Neurological disorders and treatments
- Gastric Cancer Management and Outcomes
- Magnetic confinement fusion research
- Silk-based biomaterials and applications
- Parkinson's Disease Mechanisms and Treatments
- High-Voltage Power Transmission Systems
- DNA and Nucleic Acid Chemistry
- Particle accelerators and beam dynamics
- Dermatologic Treatments and Research
- Enzyme function and inhibition
- Esophageal Cancer Research and Treatment
- Electric Motor Design and Analysis
Zhejiang University
2021-2025
Guangdong Medical College
2025
First Affiliated Hospital Zhejiang University
2024
China State Shipbuilding (China)
2024
Shanghai Power Equipment Research Institute
2024
Hangzhou Academy of Agricultural Sciences
2021
Dietary factors can significantly affect the development of gastric and colorectal cancers; however, observational findings on impact micronutrients macronutrients risk cancers are inconsistent. It is crucial to clarify these relationships create nutritional recommendations for cancer prevention. A two-sample Mendelian randomization investigation was performed examine circulating levels 15 (such as vitamin A, folate, B6, B12, C, D, E, β-carotene, calcium, copper, iron, magnesium, phosphorus,...
The alpha-synuclein (α-syn) oligomers hold a central role in the pathology of Parkinson's disease (PD). Achieving accurate detection α-syn vivo presents promising avenue for early and diagnosis PD. Magnetic resonance imaging (MRI), with non-invasion exceptional tissue penetration, offers potent tool visualizing vivo. Nonetheless, ensuring diagnostic specificity remains formidable challenge. Herein, novel MRI probe (ASOSN) is introduced, which encompasses highly sensitive antiferromagnetic...
Replication stress (RS) induced by DNA damage plays a significant role in conferring the anticancer effects of radiotherapy and is tightly associated with radioresistance cancer cells. Amplification RS represents an effective approach to improving efficacy radiotherapy, although development selective amplifiers remains unexplored frontier. We herein present nano amplifier (RSNA) consisting catalytic FePt nanoparticle loaded chemotherapeutic doxorubicin (DOX), which selectively exacerbates...
Abstract Cell cycle checkpoint activation promotes DNA damage repair, which is highly associated with the chemoresistance of various cancers including acute myeloid leukemia (AML). Selective cell inhibitors are strongly demanded to overcome chemoresistance, but remain unexplored. A selective nano inhibitor (NCCI: citric acid capped ultra‐small iron oxide nanoparticles) that can catalytically inhibit AML boost chemotherapeutic efficacy genotoxic agents now reported. NCCI selectively...
Abstract In living systems, potassium ion (K + ) plays a vital role in variety of physiological functions, whose dyshomeostasis has been seen as biomarker many diseases. Consequently, real‐time monitoring K dynamics would benefit disease diagnosis and offer insight into the pathogenic mechanisms well progression By learning from ‐specific substances nature, such ionophores, channels DNA G‐quadruplex, this perspective introduces ingenious designs, imaging functionalities, response principles...
Androgenetic alopecia (AGA) is a prevalent issue affecting the physical and mental health of individuals but with fewer current treatments. Platinum nanozymes (PtNZs) are known for their excellent ability to reduce modulate high oxidative stress environment in AGA pathology. And microneedles used overcome skin barrier due poor permeability PtNZs. Herein, dissolving loaded PtNZs (Pt-MNs) designed successfully induced hair regeneration model. Pt-MNs possessed adequate mechanical strength...
Nano Cell Cycle Checkpoint Inhibitors In article number 2300736, Daishun Ling, Fangyuan Li, and co-workers demonstrate that ultra-small iron oxide nanoparticles (IONPs) can serve as a selective nano cell cycle checkpoint inhibitor (NCCI) to catalyze the intracellular H2O2 into abundant ·OH, cleave heat shock protein 90 (Hsp90), thus induce degradation of client ATR/CHK1, leading dysfunction G2/M in acute myeloid leukemia (AML) cells. As result, NCCI interfere with chemotherapy-induced DNA...
Abstract Operative therapy for superficial esophagus carcinoma is the main way to treat disease. Endoscopic excision of lesions in has become an alternative surgical treatment patients with esophageal carcinoma. To overcome disadvantages endoscope mucosa (EMR), endoscopic submucosal dissection (ESD) technique been developed. Although ESD one most effective methods endoscopy digestive tract tumors, there are potential complications after surgery, including hemorrhage area and stenosis...