Bingru Zhao

ORCID: 0009-0004-0140-8654
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About
Contact & Profiles
Research Areas
  • Genetic and phenotypic traits in livestock
  • Cancer-related molecular mechanisms research
  • Genetic Mapping and Diversity in Plants and Animals
  • Hair Growth and Disorders
  • Animal Genetics and Reproduction
  • Reproductive Physiology in Livestock
  • Molecular Biology Techniques and Applications
  • Genomics and Phylogenetic Studies
  • Reproductive Biology and Fertility

Nanjing Agricultural University
2024-2025

China Agricultural University
2022-2024

Shandong Academy of Agricultural Sciences
2022

Xinjiang Agricultural University
2022

Xinjiang Academy of Animal Science
2022

Abstract The Farm Animal Genotype-Tissue Expression (FarmGTEx) project has been established to develop a public resource of genetic regulatory variants in livestock, which is essential for linking polymorphisms variation phenotypes, helping fundamental biological discovery and exploitation animal breeding human biomedicine. Here we show results from the pilot phase PigGTEx by processing 5,457 RNA-sequencing 1,602 whole-genome sequencing samples passing quality control pigs. We build pig...

10.1038/s41588-023-01585-7 article EN cc-by Nature Genetics 2024-01-01

Sheep (Ovis aries) represents one of the most important livestock species for animal protein and wool production worldwide. However, little is known about genetic biological basis ovine phenotypes, particularly those high economic value environmental impact. Here, by integrating 1413 RNA-seq samples from 51 distinct tissues across 14 developmental time points, representing early prenatal, late neonate, lamb, juvenile, adult, elderly stages, we built a high-resolution Gene Expression Atlas...

10.1093/gpbjnl/qzaf020 article EN cc-by Genomics Proteomics & Bioinformatics 2025-03-04

Abstract The Farm animal Genotype-Tissue Expression (FarmGTEx, https://www.farmgtex.org/) project has been established to develop a comprehensive public resource of genetic regulatory variants in domestic species, which is essential for linking polymorphisms variation phenotypes, helping fundamental biology discovery and exploitation breeding human biomedicine. Here we present results from the pilot phase PigGTEx (http://piggtex.farmgtex.org/), where processed 9,530 RNA-sequencing 1,602...

10.21203/rs.3.rs-2261680/v1 preprint EN cc-by Research Square (Research Square) 2022-11-25

Abstract Sheep ( Ovis aries ) represents one of the most important livestock species for animal protein and wool production worldwide. However, little is known about genetic biological basis ovine phenotypes, particularly those high economic value environmental impact. Here, by generating integrating 1,413 RNA-seq samples from 51 distinct tissues across 14 developmental time points, representing early prenatal, late neonate, lamb, juvenile, adult, elderly stages, we built a high-resolution...

10.1101/2024.11.14.623505 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-11-14

<title>Abstract</title> Chicken is a valuable model for understanding fundamental biology and vertebrate evolution, as well major source of nutrient-dense lean-protein-enriched food globally. Although it the first non-mammalian amniote genome to be sequenced, chicken still lacks systematic characterization functional variation. Here, through integrating bulk RNA-Seq 7,015 samples, single-cell 127,598 cells 2,869 whole-genome sequences, we presented an atlas regulatory variants across 28...

10.21203/rs.3.rs-3349515/v1 preprint EN cc-by Research Square (Research Square) 2023-09-26

Abstract Background Merino sheep have high wool production and excellent quality. The fleece of the is composed predominantly fibers grown from hair follicles (HFs). follicle a complex biological system involved in dynamic process governed by gene regulation. However, expression regulated microRNAs (miRNAs). miRNA inhibits posttranscriptional specifically binding to target messenger RNA (mRNA) plays an important role regulating expression, cell cycle development sequences. purpose this study...

10.21203/rs.3.rs-1763106/v1 preprint EN cc-by Research Square (Research Square) 2022-07-01
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