A5100344519- RNA modifications and cancer
- Cancer-related gene regulation
- Cancer-related molecular mechanisms research
- Smart Grid Security and Resilience
- Adipose Tissue and Metabolism
- Crustacean biology and ecology
- Cardiovascular Disease and Adiposity
- Computer Graphics and Visualization Techniques
- 3D Shape Modeling and Analysis
- Advanced Numerical Analysis Techniques
- Aquaculture Nutrition and Growth
- Ubiquitin and proteasome pathways
- Epigenetics and DNA Methylation
- RNA Research and Splicing
- Health and Lifestyle Studies
- Human Motion and Animation
- Genetics, Aging, and Longevity in Model Organisms
- Energy Load and Power Forecasting
- Neurobiology and Insect Physiology Research
- Video Analysis and Summarization
- Soil Mechanics and Vehicle Dynamics
- Muscle Physiology and Disorders
- Adipokines, Inflammation, and Metabolic Diseases
- Agricultural Engineering and Mechanization
- Hair Growth and Disorders
Zhejiang University
2006-2024
Hangzhou Cancer Hospital
2024
Hangzhou First People's Hospital
2024
Poultry Research Institute
2024
Guangdong Academy of Agricultural Sciences
2024
Ministry of Agriculture and Rural Affairs
2015-2024
Key Laboratory of Guangdong Province
2024
Chinese Academy of Fishery Sciences
2022-2024
Wuhan National Laboratory for Optoelectronics
2024
Huazhong University of Science and Technology
2021-2024
The smart home service is a key part of the grid consumption. It real-time interactive response between power and users, enhances comprehensive capability grid, also realizes intelligent use electricity, further improves operation mode users’ Use patterns to improve end-user energy efficiency. residential-based platform that uses IoT, computer technology, control image display technology communication connect various facilities through network meet automation requirements entire system...
Abstract In this study, we first described the complete mitochondrial genome for red crab ( Charybdis feriata ), elucidated its phylogenetic relationship among 20 species within Decapoda and estimated population genetic diversity. The was 15,660 bp in size encoded 13 protein-coding genes, 22 transfer RNA (tRNA) genes two ribosomal genes. gene arrangement of same as that sister species, C. japonica . Phylogenomic analysis suggested genus should be classified into subfamily Portuninae but not...
5-Methylcytosine (m5C) is a type of RNA modification that exists in tRNAs and rRNAs was recently found mRNA. Although mRNA m5C has been reported to regulate diverse biological process, its function adipogenesis remains unknown. Here, we demonstrated knockdown NOL1/NOP2/Sun domain family member 2 (NSUN2), methyltransferase, increased lipid accumulation 3T3-L1 preadipocytes through accelerating cell cycle progression during mitotic clonal expansion (MCE) at the early stage adipogenesis....
Abstract Background Obesity leads to a decline in the exercise capacity of skeletal muscle, thereby reducing mobility and promoting obesity-associated health risks. Dietary intervention has been shown be an important measure regulate muscle function, previous studies have demonstrated beneficial effects docosahexaenoic acid (DHA; 22:6 ω-3) on function. At molecular level, DHA its metabolites were extensively involved regulating epigenetic modifications, including DNA methylation, histone...
The desirable sowing period for winter wheat is very short in the rice-wheat rotation areas. There are also lots of straw left harvested land. Deep rotary tillage can cover rice under surface to increase soil organic matter. Clarifying effect blade on and straw, as well analyzing movement patterns forces soil, essential investigate deep process order solve problems energy consumption poor burial machinery. In this study, we built interaction model blade-soil-straw through discrete element...
Cuproptosis is an emerging mode of programmed cell death for tumor suppression but sometimes gets resisted by cells resist under specific mechanisms. Inhibiting copper transporter ATPase (ATP7A) was found to disrupt ion homeostasis, thereby enhancing the effect cuproptosis and eventually inhibiting invasion metastasis. In this study, we develop a multifunctional nanoplatfrom based on Cu9S8 (CAPSH), designed enhance in specifically targeting ATP7A interference, while combining thermodynamic...
Obesity and type 2 diabetes (T2D) are the leading causes of progressive decline in muscle regeneration fitness adults. The microenvironment is known to play a key role controlling stem cell regenerative capacity, yet underlying mechanism remains elusive. Here, we found that Baf60c expression skeletal significantly downregulated obese T2D mice humans. Myofiber-specific ablation impairs contraction, accompanied by robust upregulation Dkk3, muscle-enriched secreted protein. Dkk3 inhibits...
MicroRNA-34a (miR-34a) is expressed in the myocardium and expression altered after myocardial injury. We investigated effects of miR-34a on heart function ischemia-reperfusion (IR) Cardiomyocytes were isolated from neonatal rat hearts simulated IR injury was induced vitro. Following rats, infarct size measured left ventricular (LV) evaluated using echocardiography. Protein silent information regulator 1 (SIRT1), acetylated p53 (ac-p53), Bcl-2 Bax, SIRT1 gene levels analyzed. overexpression...
The design of communication infrastructure in cyber physical system (CPS) is vital importance for proper operations dynamics. In this paper, the scheduling packet transmission over wireless networks CPS studied purpose state stabilization. To measure effective information amount different packets, concept virtual queue (VQ) defined based on delay-tolerant Kalman filtering. VQ-based back pressure algorithm proposed distributed data traffic scheduling. impact delays VQ lengths also formulation...
Variability in food availability leads to condition-dependent investments reproduction. This study is aimed at understanding the metabolic response and regulatory mechanism of female
Increasing evidence shows that telomere length shortening is associated with the risk for Alzheimer’s disease (AD), pointing to a potential modifiable target prevention. However, causality of this association still not clear. To investigate causal relationship between and AD, we use two-sample Mendelian randomization (MR) assessing inference. We used summary-level data (9190 participants) AD (71,880 cases 383,378 controls). performed MR analysis single nucleotide polymorphisms previously...
Abstract Short-term forecasting of futures market is valuable and also a technical challenge. In this paper, hybrid approach for soybean oil price proposed based on time-series analysis methods. The method combines wavelet transformation exponential smoothing so that the characteristics time series can be captured at different scales, applied each scale. A comparative case study then conducted compares with other three methods which are an RNN network Long Short-Term Memory units,...
Obesity has become a health threat and hard enough to deal with. Evidences show that metformin could inhibit adipogenesis combat obesity, while its mechanisms remain be elucidated more comprehensively. In this study, we found administration of obesity mice induced by high-fat diet (HFD), indicated strikingly decreased body weight inguinal white adipose tissue (iWAT) epidydimal (eWAT) compared with the control group. Mechanically, revealed protein expression FTO, leading increased m6A...
The mud crab, Scylla paramamosain, has abundant nutrients in the ovary, where numerous lipids accumulate during ovarian maturation. However, mechanism behind accumulation of ovary crab maturation is largely unknown. This study conducted a comparative transcriptome analysis ovaries crabs at various stages A total 63.69 Gb clean data was obtained, with Q30 93.34%, and 81,893 unigenes were identified, including 10,996 differentially expressed genes (DEGs). After KEGG enrichment these DEGs, MAPK...