A5111730351- Dialysis and Renal Disease Management
- Central Venous Catheters and Hemodialysis
- Muscle and Compartmental Disorders
- Erythropoietin and Anemia Treatment
- Dermatology and Skin Diseases
- Parathyroid Disorders and Treatments
- Psoriasis: Treatment and Pathogenesis
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Urticaria and Related Conditions
- Pharmacological Effects and Toxicity Studies
- Renal Transplantation Outcomes and Treatments
- Hepatitis B Virus Studies
- Iron Metabolism and Disorders
- Magnesium in Health and Disease
- Potassium and Related Disorders
- Hepatitis C virus research
- Multiple Myeloma Research and Treatments
- IL-33, ST2, and ILC Pathways
- Vascular anomalies and interventions
- Heart Failure Treatment and Management
- Cardiac Arrhythmias and Treatments
- Extracellular vesicles in disease
- Organ Donation and Transplantation
- Vascular Procedures and Complications
- Immune cells in cancer
Hospital Universitario Reina Sofía
2004-2025
Instituto Maimónides de Investigación Biomédica de Córdoba
2024
Biomedical Research Institute
2024
Spanish Clinical Research Network
2024
Instituto de Salud Carlos III
2024
Hospital Clínic de Barcelona
2014-2024
Universitat de Barcelona
2024
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2024
Hospital de Clínicas
2019
Pediatric Nephrology of Alabama
2014-2016
The objective of this protocol is to know which tests are needed study an anemia in a patient with chronic kidney disease, the differential diagnosis renal anemia, and correct other deficiency anaemias, criteria for referral Nephrology or specialties anemic disease. El objetivo del protocolo es conocer qué estudios deben solicitarse ante una en un paciente con enfermedad crónica, el diagnóstico diferencial de la renal, y corregir otras anemias carenciales los criterios remisión anémico...
We studied the relationship between microinflammation and endothelial damage in chronic kidney disease (CKD) patients on different dialysis modalities.Four groups of CKD stage 5 were studied: 1) 14 nondialysis (CKD-NonD); 2) 15 hemodialysis (HD); 3) 12 peritoneal with residual renal function >1 ml/min (PD-RRF >1); 4) 13 <or=1 <or=1). Ten healthy subjects served as controls. CD14(+)CD16(+) cells apoptotic microparticles (EMPs) measured by flow cytometry. Serum vascular growth factor (VEGF)...
Recent publications show that elevation of FGF23 is independently associated with progression or renal disease, left ventricular hypertrophy and cardiovascular mortality. Dietary restriction phosphate binders are used for control balance serum levels. The aim this study to compare the effectiveness calcium carbonate vs. lanthanum in reducing levels Chronic Kidney Disease (CKD) patients.32 patients from Nephrology outpatient clinic CKD 4 - 5 non-dialysis were included. Patients receive a...
El objetivo del protocolo es conocer qué estudios deben solicitarse ante una anemia en un paciente con enfermedad renal crónica, el diagnóstico diferencial de la renal, y corregir otras anemias carenciales los criterios remisión anémico crónica a Nefrología u especialidades. The objective of this protocol is to know which test are needed study an anaemia in patient with chronic kidney disease, the differential diagnosis anaemia, and correct other deficiency anaemias, criteria for referral...
Chronic kidney disease-associated pruritus (CKD-aP), a persistent itching sensation, is prevalent among hemodialysis patients. This study aims to understand its prevalence, possible association with selected solutes, and impact on quality of life (QoL) in Involving 434 patients Spain, this observational employed survey based validated assessment tools, alongside demographic, clinical, biochemical data collection. The used statistical analyses examine the correlation between CKD-aP various...
La hemodiafiltración on-line (HDF-OL) es actualmente la técnica más efectiva. Varios estudios aleatorizados y metaanálisis han observado una reducción de mortalidad, objetivándose asociación en relación directa con el volumen convectivo. En momento presente no está bien establecido si aumento superficie del dializador puede suponer mejores resultados términos eficacia convectiva depurativa. El objetivo estudio fue valorar efecto sobre convectivo capacidad Se incluyeron 37 pacientes (31...
Abstract The evidence about the effectiveness and safety of oral anticoagulation in patients on hemodialysis is conflicting scarce. Percutaneous left atrial appendage occlusion (LAAO) has demonstrated to be a valid alternative therapeutic option for stroke prevention with nonvalvular fibrillation (NVAF). aim this study present outcomes percutaneous LAAO end‐stage renal disease (ESRD) NVAF our center. We conducted retrospective review clinical records, demographics, procedure, complications,...
Background: Hemodialysis (HD) and plasmapheresis (PE) are usually performed independently on patients who require renal replacement therapy. We analyzed our experience using a technique that performs both modalities simultaneously. Methods: Thirty-six were treated with 287 tandem PE HD (TPH) sessions (mean 7.97 ± 5.6 per patient) included. was connected 30 min after started. The mean blood flow 313.7 44 mL/min, the 141 25 duration of TPH no longer than 240 min. heparin dose similar to used...
<b><i>Background:</i></b> Etelcalcetide is a novel second-generation calcimimetic that, because of its intravenous administration, could improve treatment adherence in secondary hyperparathyroidism (SHPT). The aim this study was to evaluate the effectiveness etelcalcetide compared with that cinacalcet controlling SHPT patients under hemodialysis. <b><i>Methods:</i></b> A prospective observational performed 29 hemodialysis who switched from...
The repair of the endothelium after inflammatory injury is essential to maintaining homeostasis. link between inflammation-induced endothelial damage and has not been fully characterized in vivo. We have developed a rat model evaluate coupling lipopolysaccharide (LPS)-induced repair. Aortic was analyzed by both inmunohistochemistry flow cytometry quantify number cells percentage apoptotic cells. also identified circulating angiogenic capable repairing damaged endothelium. Erythropoietin...
Online haemodiafiltration (OL-HDF) is currently the most effective dialysis technique that also improves survival. To date, high permeability membranes with low albumin loss, such as polysulfone, polyamide and polyacrylonitrile have been widely used. However, initially restricted use of cellulose triacetate (CTA) in OL-HDF has expanded. The aim study was to ascertain whether latest generation asymmetric CTA are more obtaining convective transport.A total 16 patients (10 males 6 females)...
Currently, on-line hemodiafiltration (HDF-OL) is the most effective technique. Several randomized studies and meta-analyses have shown a reduced mortality direct association with convective volume has been reported. At present, it not established if an increased dialysate flow (Qd) results in improved terms of depurative efficiency. We aim at assessing effects Qd variations on its capacity patients HDF-OL.A total 59 (45 men 14 women) from HDF-OL programme which monitor 5008 Cordiax...
Definido como la sensación desagradable que provoca el deseo de rascarse, prurito es síntoma cutáneo más frecuente asociado a uremia, pudiendo aparecer en casi mitad los pacientes con enfermedad renal crónica (ERC) avanzada. Más allá su repercusión directa sobre calidad vida, ERC (Pa-ERC) un predictor independiente mortalidad además ejerce efecto sinérgico otros síntomas también relacionados depresión y insomnio. Aunque se han propuesto diferentes mecanismos para explicar origen,...
Aims SNF472 is a calcification inhibitor that being studied as novel treatment for calciphylaxis and cardiovascular (CVC). A first study showed acceptable safety tolerability in single ascending dose administration healthy volunteers haemodialysis (HD) patients. This aimed to assess the safety, tolerability, pharmacokinetics/pharmacodynamics relationship of intravenous HD patients multiple trial with 5 doses tested 1 week (3 administrations) 4 weeks (12 administrations). Methods double...
Serum magnesium disturbances are common in patients with cardiovascular disease (CVD). However, the well-established link between low serum and nutritional or inflammatory disorders has limited its consideration as a non-traditional risk factor for mortality. This study aims to elucidate relationship concentrations mortality due fatal heart failure (HF), coronary (CHD) stroke non-dialysis chronic kidney (CKD) stages 4 5. A cohort of 1271 CKD 5 was followed from 2008 2018. Patients prior...
<b><i>Background:</i></b> New haemodialysis therapeutic regimens are required to improve patient survival. Longer and more frequent dialysis sessions have produced excellent survival clinical advantages, while online haemodiafiltration (OL-HDF) provides the most efficient form of treatment. <b><i>Methods:</i></b> In this single-centre observational study, 57 patients on 4-5-hour thrice-weekly OL-HDF were switched nocturnal every-other-day...