A5103023855- DNA and Nucleic Acid Chemistry
- Thermal properties of materials
- Advanced biosensing and bioanalysis techniques
- Nanoplatforms for cancer theranostics
- Graphene research and applications
- Alcohol Consumption and Health Effects
- Advanced Thermoelectric Materials and Devices
- Esophageal Cancer Research and Treatment
- MXene and MAX Phase Materials
- Liver Disease Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- RNA Interference and Gene Delivery
- Tribology and Wear Analysis
- Advanced Optical Sensing Technologies
- Metal complexes synthesis and properties
- Surface Modification and Superhydrophobicity
- Ga2O3 and related materials
- Graphene and Nanomaterials Applications
- Radiomics and Machine Learning in Medical Imaging
- ZnO doping and properties
- Random lasers and scattering media
- Radiation Therapy and Dosimetry
- Advanced Image Processing Techniques
- Oceanographic and Atmospheric Processes
- Thermal Radiation and Cooling Technologies
Second People's Hospital of NanTong
2025
Nantong University
2025
First Affiliated Hospital of Xi'an Jiaotong University
2022-2024
Ministry of Agriculture and Rural Affairs
2024
Xinjiang Academy of Agricultural and Reclamation Science
2024
Tongji University
2022-2024
Sichuan Agricultural University
2024
Chinese Academy of Sciences
2009-2023
Institute of High Energy Physics
2021-2023
Chengdu Fifth People's Hospital
2023
High-performance thermal management materials are essential in miniaturized, highly integrated, and high-power modern electronics for heat dissipation. In this context, the large interface resistance (ITR) that occurs between fillers organic matrix polymer-based nanocomposites greatly limits their conductive performance. Herein, through-plane direction aligned three-dimensional (3D) MXene/silver (Ag) aerogels designed as transferring skeletons epoxy nanocomposites. Ag nanoparticles (NPs)...
Metastasis of breast carcinoma is commonly realized through lymphatic circulation, which seriously threatens the lives cancer patients. Therefore, efficient therapy for both primary tumor and metastatic sentinel lymph nodes (SLNs) highly desired to inhibit growth metastasis. During treatment, radiotherapy (RT) a common clinical method. However, efficacy RT decreased by radioresistance hypoxic microenvironment inevitable side effects healthy issues at high radiation doses. Considering...
Abstract Radiation dermatitis is a common but torturous side effect during radiotherapy, which greatly decreases the life quality of patients and potentially results in detrimental cessation tumor treatment. Fullerenol, known as “free radical sponge,” great choice for skin radioprotection because its broad‐spectrum free scavenging performance, good chemical stability, biosafety. In this work, facile scalable eco‐friendly synthetic method fullerenols by catalyst assistant mechanical chemistry...
Abstract A key characteristic of radiation‐induced oral mucositis (RIOM) is oxidative stress mediated by the “reactive oxygen species (ROS) storm” generated from water radiolysis, resulting in severe pathological lesions, accompanied a disturbance microbiota. Therefore, sprayable situ hydrogel loaded with “free radical sponge” fullerenols (FOH) developed as antioxidant agent for RIOM radioprotection. Inspired marine organisms, 3,4,5‐trihydroxyphenylalanine (TOPA) which enriched ascidians...
Abstract Background Colorectal cancer (CRC) is a complex malignancy characterized by diverse molecular profiles, clinical outcomes, and limited precision in prognostic markers. Addressing these challenges, this study utilized multi-omics data to define consensus subtypes CRC elucidate their association with outcomes underlying biological processes. Methods Consensus were obtained applying ten integrated clustering algorithms analyze TCGA-CRC data, including mRNA, lncRNA, miRNA, DNA...
Structural properties of single lambda DNA treated with anti-cancer drug cisplatin were studied magnetic tweezers and AFM. Under the effect low-concentration cisplatin, became more flexible, persistence length decreased significantly from approximately 52 to 15 nm. At a high concentration, condensation phenomenon was observed. Based on experimental results both single-molecule AFM studies, we propose model explain this kind by cisplatin: first, di-adducts induce local distortions DNA. Next,...
Oral squamous cell carcinoma (OSCC) is one of the most common oral malignancies. Radiotherapy primary noninvasive treatment OSCC for avoiding surgery-induced facial deformities and impaired function. However, specificity in situ limits radiotherapeutic effects because hypoxia-induced low radiosensitivity tumors radiation tolerance surrounding normal tissues. Here, we design a highly efficient low-toxic radiosensitization strategy. On hand, biocompatible poly(vinyl pyrrolidone)-modified...
Preeclampsia (PE) is one of the leading causes maternal and perinatal mortality morbidity. One main hallmarks observed in PE impaired inflammation state. In current study, we found that miR-125b was deregulated placental tissues plasma derived from patients, which suggest a potential association between this miRNA pathogenesis PE. Overexpression significantly reduced SGPL1 expression, luciferase assays confirmed direct target miR-125b. We also enhanced IL-8 production by directly targeting...
Neointima formation and atherosclerosis are the main complications after endovascular intervention vascular surgery, there no effective drugs. Propolis is a kind of resin substance produced by honeybees has numerous health-beneficial effects. In this study, we evaluated effects propolis (125 250 mg·kg–1·day–1, 6 weeks) on carotid restenosis in hypercholesterolemia rabbits. significantly ameliorated degree restenosis, inhibited neointima hyperplasia, reduced serum lipids profile, enhanced...
Non-alcoholic steatohepatitis (NASH) is a prevalent chronic liver disease that lacks effective treatment. In this study, the anti-NASH effects of four flavonoids (pinocembrin, galangin, chrysin, and naringenin) rich in propolis were investigated an vitro NASH model established free fatty acids (FFAs)-stimulated HepG2 cells. Using co-treatment approach, our results showed naringenin possessed strongest efficacy by significantly counteracting FFAs-induced lipid accumulation, oxidative...
Abstract Ever‐increasing packaging and power densities of modern electronic devices in the present “More‐than‐Moore” technology era demand higher performance thermal interface materials (TIMs). However, conventional composite TIMs require loading to achieve better conductive property, resulting a mechanical problem. The poor wetting property matrix further increases interfacial resistance (ITR). In this work, one‐step hydrothermal method is employed grow 2D molybdenum disulfide (MoS 2 )...
Radiotherapy benefits patients with advanced esophageal squamous cell carcinoma (ESCC) in terms of symptom relief and long-term survival. In contrast, a substantial proportion ESCC have not benefited from radiotherapy. This study aimed to establish validate an artificial neural network-based radiomics model for the pretreatment prediction radiotherapy response by using integrated data combined feasible baseline characteristics computed tomography. A total 248 who underwent CT received were...
The interactions of DNA with oxaliplatin (Pt(R,R-DACH)) or its enantiomer (Pt(S,S-DACH)) were investigated using magnetic tweezers and atomic force microscope. In the process condensation induced by Pt-DACH, only diadducts micro-loops are formed at low Pt-DACH concentrations, while high besides micro-loops, long-range cross-links also formed. diadduct formation rate Pt(R,R-DACH) is higher than that Pt(S,S-DACH). However, proportions for Pt(S,S-DACH) those Pt(R,R-DACH). We propose a model to...
ABSTRACT Heat removal via thermal management materials is attracting more and attention in the electronic industry. Conventional particle/polymer conductive composites require a high filler loading ratio (>30 vol %), which cause severe interfacial resistance mechanical issue. In this work, we fabricate tellurium nanowires (NWs)/epoxy nanocomposites facile bar coating method. According to Agari model Maxwell–Eucken model, as‐synthesized ultra‐long NWs with aspect (>100) construct 3D...