A5100685541- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Human Pose and Action Recognition
- Prenatal Screening and Diagnostics
- Hand Gesture Recognition Systems
- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Airway Management and Intubation Techniques
- Genomic variations and chromosomal abnormalities
- Head and Neck Surgical Oncology
- Tracheal and airway disorders
- Advanced Neuroimaging Techniques and Applications
- Advanced Radiotherapy Techniques
- Sarcoma Diagnosis and Treatment
- Parathyroid Disorders and Treatments
- Gastrointestinal Tumor Research and Treatment
- Congenital Anomalies and Fetal Surgery
- Fetal and Pediatric Neurological Disorders
- Biochemical effects in animals
- Electrolyte and hormonal disorders
- Hepatocellular Carcinoma Treatment and Prognosis
- Thyroid Cancer Diagnosis and Treatment
- Diabetic Foot Ulcer Assessment and Management
- Nanoplatforms for cancer theranostics
- Helicobacter pylori-related gastroenterology studies
Hunan Cancer Hospital
2025
Xiangya Hospital Central South University
2021-2025
Central South University
2020-2025
Heilongjiang University
2025
First Bethune Hospital of Jilin University
2023-2024
Chinese Academy of Sciences
2022-2024
Yale University
2024
Anhui University
2022-2024
Second Affiliated Hospital of Jilin University
2024
Shenzhen Institutes of Advanced Technology
2023-2024
Abstract Candida albicans ( C. ), a ubiquitous polymorphic fungus in humans, causes different types of candidiasis, including oral candidiasis (OC) and vulvovaginal (VVC), which are physically mentally concerning financially costly. Thus, developing alternative antifungals that prevent drug resistance induce immunity to eliminate biofilms is crucial. Herein, novel membrane‐targeted aggregation‐induced emission (AIE) photosensitizer (PS), TBTCP‐QY, developed for highly efficient photodynamic...
Markerless pose estimation based on computer vision provides a simpler and cheaper alternative to human motion capture, with great potential for clinical diagnosis remote rehabilitation assessment. Currently, the markerless 3D is mainly multi-view technology, while more promising single-view technology has defects such as low accuracy reliability, which seriously limits application. This study proposes high-resolution graph convolutional multilayer perception (HGcnMLP) framework smartphone...
Immunotherapy shows remarkable benefits in treating melanoma, yet existing approaches achieve limited overall responses. Here, we show that a combination of bromodomain and extra-terminal protein family inhibitor, NHWD-870, Bacillus Calmette-Guérin vaccine is promising therapeutic strategy for melanomas. Single-cell transcriptome analyses functional experiments the therapy significantly inhibited tumor growth by reprogramming T cells toward an immune-activated state, enhancing their...
Secondary hyperparathyroidism (SHPT) usually requires parathyroidectomy when drug regimens fail. However, obtaining an exact preoperative map of the locations parathyroid glands is a challenge. The purpose this study was to compare diagnostic performance US, dual-phase 99mTc-MIBI scintigraphy, early and delayed SPECT/CT in patients with SHPT.Sixty SHPT who were undergoing dialysis evaluated preoperatively by SPECT/CT. Postoperative pathology served as gold standard. sensitivity, specificity,...
Objective: This study aims to estimate the prevalence and risk factors of macrosomia LGA (large for gestational age) in non-GDM (gestational diabetes mellitus) pregnant women Fuyang, Anhui Province China.Methods: A large population-based cohort was conducted among aged 18–45 years. Maternal sociodemographic data prior pregnancy were collected using interviewer-administered standardized questionnaire. obstetrical delivery records newborn hospital extracted from antenatal care booklets...
Background The coexistence of heart failure and diabetes is prevalent, particularly in Intensive Care Units (ICU). However, the relationship between triglyceride-glucose (TyG) index, failure, diabetes, length hospital stay (LHS) patients with cerebrovascular disease ICU remains uncertain. This study aims to investigate association TyG index LHS diabetes. Methods retrospective utilized Medical Information Mart for (MIMIC)-IV database analyze failure. Participants were categorized into...
We evaluated intratumor (IT) versus intravenous (IV) administration of the photosensitizer Pc 4 with respect to tumor concentration, specificity, and responses irradiation. BALB/c mice bearing intradermal EMT6 tumors were given 0.3 mg/kg injected IT or IV through tail vein. Photosensitizer concentration was by chloroform extraction localization assessed fluorescence imaging spectroscopy in vivo. Tumors irradiated at 667 nm, 50 mW/cm(2), 100 J/cm(2). Cures defined as no palpable 90 days after...
The registration of computed tomography (CT) and cone-beam (CBCT) plays a key role in image-guided radiotherapy (IGRT). However, the large intensity variation between CT CBCT images limits performance its clinical application IGRT. In this study, learning-based unsupervised approach was developed to address issue accurately register by predicting deformation field.
Serum chloride level has clinical significance in the prognosis of heart failure. Little is known regarding association between serum levels and in-hospital mortality patients with
Abstract Previous studies have reported that the significant association between serum calcium and mortality substantially in patients, especially among those with intensive care unit (ICU). And In diabetes mellitus, congestive heart failure (CHF) is a comorbidity. We aim to evaluate levels in-hospital patients failure. The participants this study were extracted from Medical Information Mart for Intensive Care IV (MIMIC-IV) database. To scrutinize potential associations mortality,...
The study aimed to investigate the clinical use of noninvasive prenatal testing (NIPT) for common fetal aneuploidies as a screening tool detection rare chromosomal abnormalities (RCAs).
Helicobacter pylori infection is a well-established etiological factor for gastric inflammation and significant risk the development of cancer. However, precise relationship between dietary zinc intake seropositivity remains uncertain.This cross-sectional observational study utilized data from United States National Health Nutrition Examination Survey conducted 1999 2000. The cohort comprised 2,884 adults aged 20 years or older who provided comprehensive 24-h recall data. presence was...
Current medical image registration methods based on Transformer still encounter challenges, including significant local intensity differences and limited computational efficiency when dealing with three-dimensional (3D) computed tomography (CT) cone beam CT (CBCT) images. These limitations hinder the precise alignment necessary for effective diagnosis treatment planning. Therefore, aim of this study is to develop a novel method that overcomes these challenges by enhancing feature interaction...
Dynamic positron emission tomography (PET) imaging can provide information about metabolic changes over time, and is widely used in clinical diagnosis cancer treatment. However, the existing deep learning methods for PET image reconstruction mainly focus on static mapping paradigm between sinogram radioactivity concentration distribution, which ignores inherent dynamic activation process of tracers. In this paper, we establish a physiological model based framework using physiology prior....
ABSTRACT Chronic pain is a significant problem that afflicts individuals and society, for which the current clinical treatment inadequate. In addition, neural circuit molecular mechanisms subserving chronic remain largely uncharacterized. Herein we identified enhanced activity of glutamatergic neuronal encompasses projections from ventral posterolateral nucleus (VPLGlu) to neurons hindlimb primary somatosensory cortex (S1HLGlu), driving allodynia in mouse models pain. Optogenetic inhibition...
Acral melanoma is the major subtype of in Chinese patients. However, a majority current studies focused on non-acral melanoma. Most immortalized cell lines and primary cells were not from acral Besides, there are rarely reports about methods for establishing cultures related animal models. Here, we present four new human lines. To determine mutational profile established future targeted use, performed exome sequencing. We next examined proliferation by colony-formation assays CCK8 assay....