Bo Li

ORCID: 0000-0003-1696-5803
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Research Areas
  • Cancer, Lipids, and Metabolism
  • Nutritional Studies and Diet
  • Obesity, Physical Activity, Diet
  • Nutrition and Health in Aging
  • Renal cell carcinoma treatment
  • Fatty Acid Research and Health
  • Smoking Behavior and Cessation
  • Liver Disease Diagnosis and Treatment
  • Global Public Health Policies and Epidemiology
  • Metabolomics and Mass Spectrometry Studies
  • RNA modifications and cancer
  • Parathyroid Disorders and Treatments
  • Biochemical Analysis and Sensing Techniques
  • Adipokines, Inflammation, and Metabolic Diseases
  • Cancer, Hypoxia, and Metabolism
  • Eating Disorders and Behaviors
  • Diet and metabolism studies
  • Osteoarthritis Treatment and Mechanisms
  • Protease and Inhibitor Mechanisms
  • Diabetes Treatment and Management
  • Inflammatory Biomarkers in Disease Prognosis
  • Sleep and related disorders
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Esophageal and GI Pathology
  • Sleep and Work-Related Fatigue

Jilin University
2013-2024

Shaanxi University of Chinese Medicine
2024

Jilin Medical University
2013-2024

Second Affiliated Hospital of Jilin University
2024

University of Bern
2023

China Medical University
2023

Chengdu Women's and Children's Central Hospital
2022

University of Electronic Science and Technology of China
2022

Second Military Medical University
2017

University of Ottawa
2017

Ferroptosis is a form of regulated necrosis associated with the iron-dependent accumulation lipid hydroperoxides that may play key role in pathogenesis degenerative diseases which peroxidation has been implicated. High-throughput screening efforts have identified ferrostatin-1 (Fer-1) and liproxstatin-1 (Lip-1) as potent inhibitors ferroptosis − an activity ascribed to their ability slow hydroperoxides. Herein we demonstrate this likely derives from reactivity radical-trapping antioxidants...

10.1021/acscentsci.7b00028 article EN publisher-specific-oa ACS Central Science 2017-03-07

Post-traumatic wound infection is commonly observed in trauma patients and has a poor prognosis. Vitamin D significant modulator of the immune system may play role preventing infection. However, inherent limitations inconsistent results previous observational studies restricted them from inferring causal effects. We employed Mendelian randomization design to estimate effects serum 25-hydroxyvitamin levels on risk post-traumatic Data analysis were extracted large-scale genome-wide association...

10.3177/jnsv.71.110 article EN Journal of Nutritional Science and Vitaminology 2025-04-29

Objectives Previous studies have reported that sleep duration might increase the risk of hypertension. However, results been conflicting. We investigated whether is independently associated with aimed to assess relationship between and hypertension in a population-based cross-sectional study. Methods In this study we used multistage stratified cluster sampling. A total 19 407 adults aged 18–79 years were enrolled The participants divided into three groups (<7 hours/day, 7–8 hours/day...

10.1136/bmjopen-2018-023916 article EN cc-by-nc BMJ Open 2019-01-01

Objectives: The present study aimed to investigate the prevalence of smoking and environmental tobacco smoke (ETS), associated factors current among adults, their attitudes perceptions towards control. Methods: A population-based cross-sectional survey was conducted in 2012 using a self-reported questionnaire. representative sample adults aged 18–79 years collected Jilin Province Northeast China by multistage stratified random cluster sampling design. Descriptive data analysis conducted, 95%...

10.3390/ijerph120708606 article EN International Journal of Environmental Research and Public Health 2015-07-22

Abstract Background The association between sensory impairment including vision (VI), hearing (HI), dual (DI) and the functional limitations of SCD (SCD-related FL) are still unclear in middle-aged older people. Methods 162,083 participants from BRFSS 2019 to 2020 was used this cross-sectional study. After adjusting weights, multiple logistic regression study relationship or SCD-related FL. In addition, we performed subgroup analysis on basis interaction covariates. Results Participants who...

10.1186/s12877-023-03950-x article EN cc-by BMC Geriatrics 2023-04-14

Image-based screening improves the detection of early-stage lung adenocarcinoma (LUAD)but also highlights issue high false-positive diagnoses, which puts patients at a risk unnecessary over-treatment. Therefore, more precise discrimination criteria are required to ensure that with LUAD receive appropriate treatments.We integrated 158 cases from 2 independent cohorts, including 30 matched resected specimens complete radiological and pathological information, 128 retrospective pair-samples...

10.1186/s13046-023-02877-w article EN cc-by Journal of Experimental & Clinical Cancer Research 2023-11-23

The present study aimed to investigate the prevalence and associated socio-demographic factors of passive smoking among women in Jilin Province, China.A cross-sectional was conducted 2012, using a self-reported questionnaire interview. A representative sample 9788 non-smoking aged 18-79 years collected Province China by multistage stratified random cluster sampling design. Descriptive data analysis 95% confidence intervals (CI) prevalence/frequency were conducted. Multivariable logistic...

10.3390/ijerph121113970 article EN International Journal of Environmental Research and Public Health 2015-10-30

The purpose of the present study was to explore potential molecular signaling pathway mediated by statin rosuvastatin in cultured human coronary artery endothelial cells (HCAECs) induced CoCl2. CoCl2 used induce apoptosis HCAECs. Myocardial infarction rats were established and received or PBS treatment. Reverse transcription‑quantitative PCR, western blotting, ELISA, TUNEL assay immunohistochemistry analyze role results showed that treatment decreased HCAECs increasing anti‑apoptosis Bcl‑xl...

10.3892/mmr.2020.11266 article EN cc-by-nc-nd Molecular Medicine Reports 2020-06-23

Abstract Previous studies have reported that the significant association between serum calcium and mortality substantially in patients, especially among those with intensive care unit (ICU). And In diabetes mellitus, congestive heart failure (CHF) is a comorbidity. We aim to evaluate levels in-hospital patients failure. The participants this study were extracted from Medical Information Mart for Intensive Care IV (MIMIC-IV) database. To scrutinize potential associations mortality,...

10.1038/s41598-024-63603-w article EN cc-by Scientific Reports 2024-06-11

Two new furostanol saponins were isolated from the fruits of Tribulus terrestris L. Their structures established as 26-O-β-d-glucopyranosyl-(25S)-5α-furost-20(22)-en-3β,26-diol-3-O-α-l-rhamnopyranosyl-(1 → 2)-[β-d-glucopyranosyl-(1 4)]-β-d-galactopyranoside (1) and 26-O-β-d-glucopyranosyl-(25S)-5α-furost-20(22)-en-12-one-3β,26-diol-3-O-β-d-galactopyranosyl-(1 2)-β-d-glucopyranosyl-(1 4)-β-d-galactopyranoside (2) on basis spectroscopic data well chemical evidence.

10.1080/10286021003747458 article EN Journal of Asian Natural Products Research 2010-05-01

Abstract Background Sleep disorders, one of the most common problems in general population, have been related to a series harmful health consequences. Vitamin D appears be associated with sleep disorders. However, difference vitamin levels between disorder subjects and people without is unclear. Simultaneously, influence replenishment on disorders remains controversial. Methods PubMed, MEDLINE, Web Science, Cochrane Library were searched for literatures published until October 2019. Using...

10.1002/fsn3.1867 article EN cc-by Food Science & Nutrition 2020-09-09

Hyperglycaemia and diabetes have become major public health problems worldwide. There is increasing evidence that minerals the vitamin B group might play specific roles in hyperglycaemia pathogenesis progression of or metabolic complications.The main aim this study to investigate effect mineral supplementation on blood glucose levels different populations.This was a cross-sectional study. Data from National Health Nutrition Examination Survey (NHANES) 2007-2014 were used A total 8,322...

10.29219/fnr.v63.3560 article EN cc-by Food & Nutrition Research 2019-12-03

Several studies have found that MMP-9, one of the extracellular matrix-degrading proteinases, was involved in EC's (endometrial cancer) clinical progression and prognosis. However, results involving associations MMP-9 expression with risk, features prognosis EC were conflicting. Therefore, we performed a systematic review meta-analysis to clarify correlation EC.Relative between retrieved from PubMed, Embase, Web Science CNKI (China National Knowledge Infrastructure) electronic databases. OR...

10.3389/fonc.2022.925424 article EN cc-by Frontiers in Oncology 2022-10-26

To determine the prevalence of high weight at different characteristics, understand perceptions and behaviours towards body weight, potential influencing factors misperception among high-weight adults in Jilin Province.A cross-sectional survey with complex sampling design was conducted. We described perception weight.Northeast China 2012.Adults (n 20 552) aged 18-79 years.Of overweight individuals, 37·4 % considered themselves as 'normal weight', 4·8 reported being 'very thin' only 53·1 were...

10.1017/s1368980017000556 article EN Public Health Nutrition 2017-04-05

Traditionally, the absence of insulin resistance risk factors (IRRFs) was considered a low for (IR). However, IR also existed in certain individuals without IRRFs; thus this study aims to explore predictors targeted at population IRRFs. Cross-sectional survey. National Health and Nutrition Examination Survey. Participants regular IRRFs (IRRF-Free, n=2478) subgroup optimal (IRRF-Optimal, n=1414) were involved study. cut-off value triglyceride (TG) predict IR. Overall, prevalence 6.9% 5.7%...

10.1136/bmjopen-2018-028652 article EN cc-by-nc BMJ Open 2019-08-01
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