- Pancreatic and Hepatic Oncology Research
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Neurotoxicity Research
- Organ Transplantation Techniques and Outcomes
- Liver Disease Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Liver Disease and Transplantation
- Bone fractures and treatments
- Esophageal and GI Pathology
- Ocular Oncology and Treatments
- Renal cell carcinoma treatment
- Immune Response and Inflammation
- Respiratory Support and Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Immunotherapy and Biomarkers
- Bone Tumor Diagnosis and Treatments
- Family and Patient Care in Intensive Care Units
- Cancer Research and Treatments
- Protein Interaction Studies and Fluorescence Analysis
- S100 Proteins and Annexins
- Sepsis Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Child Nutrition and Feeding Issues
- Machine Learning in Healthcare
Ningxia Medical University
2017-2025
Weifang Medical University
2022-2023
University of Virginia
2023
Hebei University
2022
Shanghai Jiao Tong University
2022
State Key Laboratory of Cancer Biology
2022
Shandong University
2022
The People's Hospital of Guangxi Zhuang Autonomous Region
2022
State Council of the People's Republic of China
2022
Hefei University of Technology
2022
Abstract Introduction Severe sepsis is associated with a high mortality rate despite implementation of guideline recommendations. Adjunctive treatment may be efficient and require further investigation. In light the crucial role immunologic derangement in severe sepsis, thymosin alpha 1 (Tα1) considered as promising beneficial immunomodulatory drug. The trial to evaluate whether Tα1 improves 28-day all-cause rates immunofunction patients sepsis. Methods We performed multicenter randomized...
The expansion of myeloid-derived suppressor cells (MDSCs) correlates with tumorigenesis in colorectal cancer (CRC). Here, we found a significant association between CD33+ MDSC number and Yes-associated protein 1 (YAP1) phosphatase tensin homologue (PTEN) levels CRC patients (P < 0·05). Moreover, the MDSCs, YAP1 PTEN were identified as predictors for prognosis Notably, MDSCs an independent survival predictor through Cox model analysis. In vitro data determined that expression CRC-derived cell...
OBJECTIVE: This prospective randomized study evaluated the efficacy and patient tolerance of dexmedetomidine compared with midazolam for sedation in postoperative patients undergoing flexible bronchoscopy. METHODS: A total 198 were to receive ( n = 99) or produce conscious Peripheral oxygen saturation, heart rate systolic diastolic arterial pressures recorded before, during after procedure. Patient was using various visual analogue scales. RESULTS: The mean lowest peripheral saturation...
Improvement of fat digestion and absorption was supposed to relieve feeding intolerance. This trial aimed evaluate the effect a fat-modified enteral formula on tolerance in critically ill patients.This conducted 7 hospitals China. In total, 144 intensive care unit (ICU) patients with estimated need nutrition (EN) for at least 5 days were randomly given containing medium-chain triglycerides (MCT), carnitine, taurine (interventional feed group, n = 71) or standard (control 73). EN intake,...
Nowadays, digestive tract cancers become the commonest neoplasia and one of leading causes cancer deaths worldwide. The development diagnosis therapy is urgently required. Programmed cell death 4 (PDCD4), a new tumor suppressor, has been documented to be potential diagnostic tool treatment target for due inhabitation promotion/progression metastasis. However, its role in human few available up now. In this study, we examined expression PDCD4 (61 gastric cancer, 65 colorectal 69 pancreatic...
Postoperative cognitive dysfunction (POCD) is a common complication after surgery, especially for elderly patients. Administration of RNase has been reported to exhibit neuroprotective effects in acute stroke. However, the potential role on POCD unknown. Therefore, we sought investigate whether treatment could mitigate unilateral nephrectomy induced-cognitive deficit aged mice. In present study, twelve-month-old mice were administered or an equal amount normal saline perioperatively. All...
To evaluate the relationship between plasma N-terminal prohormone B-type natriuretic peptide (NT-proBNP) and weaning outcomes, ability of NT-proBNP level to predict success, in cancer patients with pulmonary complications undergoing noncardiac major surgeries.Patients who were mechanically ventilated following postoperative respiratory failure enrolled. levels at end a 2-h spontaneous breathing trial measured. Weaning was considered success completed maintained extubation for >48 h.Out 29...
Lung ischemia-reperfusion injury (LIRI) occurs in various clinical situations, such as transplantation, cardio pulmonary bypass, cardiac arrest, and major trauma, leading to significant morbidity mortality. Despite researchers having spent years of effort investigate the pathogenesis ischemic injury, concrete cellular molecular mechanisms are still unknown. We hypothesized that toll-like receptor (TLR) 3 signaling may play a vital role inflammation responses, apoptosis, dysfunction during...
To facilitate the flame retardancy of phenolic resin (PF), a series novel retardants with nano-SiO2, melamine, and aluminum diethylphosphinate (ADP) were freshly prepared tested. A thermogravimetric analysis, cone calorimeter, scanning electron microscopy employed to determine thermal decomposition, retardancy, combustion properties, structure carbon residue layer PF. The pyrolysis kinetic parameters modified PF then computed, process was appraised. results indicated that when 1.5 wt % 3 15...
Objectives To investigate the current situation and analyze associated factors of withdrawing or withholding life support in intensive care unit (ICU) our cancer center. Methods Three hundred twenty-two patients critical status were admitted to ICU 2010 2011. They included study classified into two groups: (WWLS), full (FLS). Demographic information clinical data collected compared between groups. Factors with analyzed univariate multivariate logistic regression analysis. Results Eighty-two...
MA, G., SEGAWA, M., NOMURA, Y., KONDO, YANAGITANI, M. and HIGURASHI, The Development of Sleep-Wakefulness Rhythm in Normal Infants Young Children. Tohoku J. Exp. Med., 1993, 171 (1), 29-41-The development circadian sleep-wakefulness rhythm was investigated by a longitudinal study two normal newborns for half years transversal 182 infants young children living three different areas Japan. became established before 4 months age, daytime sleep concentrated within time periods from 7 then single...
BACKGROUNDPancreatic liposarcoma is a rare tumor.According to literature review, the patient described in this study seventh case of pancreatic reported English and third dedifferentiated liposarcoma.Furthermore, had largest primary tumor volume, was diagnosed based on sufficient evidence. CASE SUMMARYWe here report 28-year-old female with huge tail.In June 2015, underwent distal pancreatectomy splenectomy.During operation, approximately 28.0 cm × 19.0 8.0 found, which yellow white fish-like...